STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UCB |
Texto Completo: | http://twingo.ucb.br:8080/jspui/handle/10869/461 https://repositorio.ucb.br:9443/jspui/handle/123456789/7639 |
Resumo: | STING Millennium Suite (SMS) is a new web-based suite of programs and databases providing visualization and a complex analysis of molecular sequence and structure for the data deposited at the Protein Data Bank (PDB). SMS operates with a collection of both publicly available data (PDB, HSSP, Prosite) and its own data (contacts, interface contacts, surface accessibility). Biologists find SMS useful because it provides a variety of algorithms and validated data, wrapped-up in a user friendly web interface. Using SMS it is now possible to analyze sequence to structure relationships, the quality of the structure, nature and volume of atomic contacts of intra and inter chain type, relative conservation of amino acids at the specific sequence position based on multiple sequence alignment, indications of folding essential residue (FER) based on the relationship of the residue conservation to the intra-chain contacts and Cα Cα and Cβ Cβ distance geometry. Specific emphasis in SMS is given to interface forming residues (IFR)—amino acids that define the interactive portion of the protein surfaces. SMS may simultaneously display and analyze previously superimposed structures. PDB updates trigger SMS updates in a synchronized fashion. SMS is freely accessible for public data at http://www.cbi.cnptia.embrapa.br, http://mirrors.rcsb.org/SMS and http://trantor.bioc.columbia.edu/SMS. |
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Neshich, GoranTogawa, Roberto C.Mancini, Adauto L.Kuser, Paula R.Yamagishi, Michel E. B.Pappas Jr., GeorgiosTorres, Wellington V.Campos, Tharsis Fonseca eFerreira, Leonardo L.Luna, Fabio M.Oliveira, Adilton G.Miura, Ronald T.Inoue, Marcus K.Horita, Luiz G.Souza, Dimas F. deDominiquini, FabianaÁlvaro, AlexandreLima, Cleber S.Ogawa, Fabio O.Gomes, Gabriel B.Palandrani, Juliana F.Santos, Gabriela F. dosFreitas, Esther M. deMattiuz, Amanda R.Costa, Ivan C.Almeida, Celso L. deSouza, SavioBaudet, ChristianHiga, Roberto H.2016-10-10T03:52:11Z2016-10-10T03:52:11Z2003NESHICH, Goran et al. STING Millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence. Nucleic Acids Research, v. 31, p. 3386-3392, 2003.3051048http://twingo.ucb.br:8080/jspui/handle/10869/461https://repositorio.ucb.br:9443/jspui/handle/123456789/7639STING Millennium Suite (SMS) is a new web-based suite of programs and databases providing visualization and a complex analysis of molecular sequence and structure for the data deposited at the Protein Data Bank (PDB). SMS operates with a collection of both publicly available data (PDB, HSSP, Prosite) and its own data (contacts, interface contacts, surface accessibility). Biologists find SMS useful because it provides a variety of algorithms and validated data, wrapped-up in a user friendly web interface. Using SMS it is now possible to analyze sequence to structure relationships, the quality of the structure, nature and volume of atomic contacts of intra and inter chain type, relative conservation of amino acids at the specific sequence position based on multiple sequence alignment, indications of folding essential residue (FER) based on the relationship of the residue conservation to the intra-chain contacts and Cα Cα and Cβ Cβ distance geometry. Specific emphasis in SMS is given to interface forming residues (IFR)—amino acids that define the interactive portion of the protein surfaces. SMS may simultaneously display and analyze previously superimposed structures. PDB updates trigger SMS updates in a synchronized fashion. SMS is freely accessible for public data at http://www.cbi.cnptia.embrapa.br, http://mirrors.rcsb.org/SMS and http://trantor.bioc.columbia.edu/SMS.Made available in DSpace on 2016-10-10T03:52:11Z (GMT). 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dc.title.pt_BR.fl_str_mv |
STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence |
title |
STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence |
spellingShingle |
STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence Neshich, Goran Sting |
title_short |
STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence |
title_full |
STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence |
title_fullStr |
STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence |
title_full_unstemmed |
STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence |
title_sort |
STING millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence |
author |
Neshich, Goran |
author_facet |
Neshich, Goran Togawa, Roberto C. Mancini, Adauto L. Kuser, Paula R. Yamagishi, Michel E. B. Pappas Jr., Georgios Torres, Wellington V. Campos, Tharsis Fonseca e Ferreira, Leonardo L. Luna, Fabio M. Oliveira, Adilton G. Miura, Ronald T. Inoue, Marcus K. Horita, Luiz G. Souza, Dimas F. de Dominiquini, Fabiana Álvaro, Alexandre Lima, Cleber S. Ogawa, Fabio O. Gomes, Gabriel B. Palandrani, Juliana F. Santos, Gabriela F. dos Freitas, Esther M. de Mattiuz, Amanda R. Costa, Ivan C. Almeida, Celso L. de Souza, Savio Baudet, Christian Higa, Roberto H. |
author_role |
author |
author2 |
Togawa, Roberto C. Mancini, Adauto L. Kuser, Paula R. Yamagishi, Michel E. B. Pappas Jr., Georgios Torres, Wellington V. Campos, Tharsis Fonseca e Ferreira, Leonardo L. Luna, Fabio M. Oliveira, Adilton G. Miura, Ronald T. Inoue, Marcus K. Horita, Luiz G. Souza, Dimas F. de Dominiquini, Fabiana Álvaro, Alexandre Lima, Cleber S. Ogawa, Fabio O. Gomes, Gabriel B. Palandrani, Juliana F. Santos, Gabriela F. dos Freitas, Esther M. de Mattiuz, Amanda R. Costa, Ivan C. Almeida, Celso L. de Souza, Savio Baudet, Christian Higa, Roberto H. |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Neshich, Goran Togawa, Roberto C. Mancini, Adauto L. Kuser, Paula R. Yamagishi, Michel E. B. Pappas Jr., Georgios Torres, Wellington V. Campos, Tharsis Fonseca e Ferreira, Leonardo L. Luna, Fabio M. Oliveira, Adilton G. Miura, Ronald T. Inoue, Marcus K. Horita, Luiz G. Souza, Dimas F. de Dominiquini, Fabiana Álvaro, Alexandre Lima, Cleber S. Ogawa, Fabio O. Gomes, Gabriel B. Palandrani, Juliana F. Santos, Gabriela F. dos Freitas, Esther M. de Mattiuz, Amanda R. Costa, Ivan C. Almeida, Celso L. de Souza, Savio Baudet, Christian Higa, Roberto H. |
dc.subject.por.fl_str_mv |
Sting |
topic |
Sting |
dc.description.abstract.por.fl_txt_mv |
STING Millennium Suite (SMS) is a new web-based suite of programs and databases providing visualization and a complex analysis of molecular sequence and structure for the data deposited at the Protein Data Bank (PDB). SMS operates with a collection of both publicly available data (PDB, HSSP, Prosite) and its own data (contacts, interface contacts, surface accessibility). Biologists find SMS useful because it provides a variety of algorithms and validated data, wrapped-up in a user friendly web interface. Using SMS it is now possible to analyze sequence to structure relationships, the quality of the structure, nature and volume of atomic contacts of intra and inter chain type, relative conservation of amino acids at the specific sequence position based on multiple sequence alignment, indications of folding essential residue (FER) based on the relationship of the residue conservation to the intra-chain contacts and Cα Cα and Cβ Cβ distance geometry. Specific emphasis in SMS is given to interface forming residues (IFR)—amino acids that define the interactive portion of the protein surfaces. SMS may simultaneously display and analyze previously superimposed structures. PDB updates trigger SMS updates in a synchronized fashion. SMS is freely accessible for public data at http://www.cbi.cnptia.embrapa.br, http://mirrors.rcsb.org/SMS and http://trantor.bioc.columbia.edu/SMS. |
dc.description.version.pt_BR.fl_txt_mv |
Sim |
dc.description.status.pt_BR.fl_txt_mv |
Publicado |
description |
STING Millennium Suite (SMS) is a new web-based suite of programs and databases providing visualization and a complex analysis of molecular sequence and structure for the data deposited at the Protein Data Bank (PDB). SMS operates with a collection of both publicly available data (PDB, HSSP, Prosite) and its own data (contacts, interface contacts, surface accessibility). Biologists find SMS useful because it provides a variety of algorithms and validated data, wrapped-up in a user friendly web interface. Using SMS it is now possible to analyze sequence to structure relationships, the quality of the structure, nature and volume of atomic contacts of intra and inter chain type, relative conservation of amino acids at the specific sequence position based on multiple sequence alignment, indications of folding essential residue (FER) based on the relationship of the residue conservation to the intra-chain contacts and Cα Cα and Cβ Cβ distance geometry. Specific emphasis in SMS is given to interface forming residues (IFR)—amino acids that define the interactive portion of the protein surfaces. SMS may simultaneously display and analyze previously superimposed structures. PDB updates trigger SMS updates in a synchronized fashion. SMS is freely accessible for public data at http://www.cbi.cnptia.embrapa.br, http://mirrors.rcsb.org/SMS and http://trantor.bioc.columbia.edu/SMS. |
publishDate |
2003 |
dc.date.issued.fl_str_mv |
2003 |
dc.date.accessioned.fl_str_mv |
2016-10-10T03:52:11Z |
dc.date.available.fl_str_mv |
2016-10-10T03:52:11Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
status_str |
publishedVersion |
format |
article |
dc.identifier.citation.fl_str_mv |
NESHICH, Goran et al. STING Millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence. Nucleic Acids Research, v. 31, p. 3386-3392, 2003. |
dc.identifier.uri.fl_str_mv |
http://twingo.ucb.br:8080/jspui/handle/10869/461 https://repositorio.ucb.br:9443/jspui/handle/123456789/7639 |
dc.identifier.issn.none.fl_str_mv |
3051048 |
identifier_str_mv |
NESHICH, Goran et al. STING Millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence. Nucleic Acids Research, v. 31, p. 3386-3392, 2003. 3051048 |
url |
http://twingo.ucb.br:8080/jspui/handle/10869/461 https://repositorio.ucb.br:9443/jspui/handle/123456789/7639 |
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openAccess |
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Repositório Institucional da UCB |
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