Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Semina. Ciências Agrárias (Online) |
Texto Completo: | https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509 |
Resumo: | This study evaluated the efficacy of pyrantel pamoate and ivermectin on gastrointestinal nematodes in dogs. Fecal egg counts per gram (EPG) were measured by the fecal egg count reduction test (FECRT) in order to evaluate the anthelmintic efficiency and fecal float exams were also performed to assess the concordance between coproparasitological techniques. A total of 45 naturally infected dogs in the city of Bandeirantes, Paraná State, were selected and divided into three groups: Group 1, 15 animals that received pyrantel pamoate (145 mg) in a single dose; Group 2, 15 animals that received ivermectin (3 mg); and Group 3, 15 animals that comprised an untreated control group. Fecal testing was performed two and 10 days after treatment. Toxocara was the most prevalent genus, followed by Ancylostoma and Trichuris. Ancylostoma had low resistance to ivermectin and pyrantel pamoate treatment, while Toxocara were resistant to both treatments. Statistical correlation testing to compare coproparasitogical techniques revealed moderate concordance, substantial and almost perfect concordance for detection of Ancylostoma, Trichuris, and Toxocara, respectively. The results of this study suggest that the gender Ancylostoma had low resistance and Toxocara is resistant to both drugs and because of their high prevalence in young animals means that others anthelmintic drugs may be recommended to combat infections. Additionally, the Gordon and Whitlock modified and Willis-Mollay techniques are effective for detection particularly of Toxocara in dogs. |
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Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodesEficácia do pamoato de pirantel e da ivermectina no tratamento de nematódeos caninosAncylostomiasisDogsParasitic resistanceToxocariasis.AncilostomíaseCãesResistência parasitáriaToxocaríase.This study evaluated the efficacy of pyrantel pamoate and ivermectin on gastrointestinal nematodes in dogs. Fecal egg counts per gram (EPG) were measured by the fecal egg count reduction test (FECRT) in order to evaluate the anthelmintic efficiency and fecal float exams were also performed to assess the concordance between coproparasitological techniques. A total of 45 naturally infected dogs in the city of Bandeirantes, Paraná State, were selected and divided into three groups: Group 1, 15 animals that received pyrantel pamoate (145 mg) in a single dose; Group 2, 15 animals that received ivermectin (3 mg); and Group 3, 15 animals that comprised an untreated control group. Fecal testing was performed two and 10 days after treatment. Toxocara was the most prevalent genus, followed by Ancylostoma and Trichuris. Ancylostoma had low resistance to ivermectin and pyrantel pamoate treatment, while Toxocara were resistant to both treatments. Statistical correlation testing to compare coproparasitogical techniques revealed moderate concordance, substantial and almost perfect concordance for detection of Ancylostoma, Trichuris, and Toxocara, respectively. The results of this study suggest that the gender Ancylostoma had low resistance and Toxocara is resistant to both drugs and because of their high prevalence in young animals means that others anthelmintic drugs may be recommended to combat infections. Additionally, the Gordon and Whitlock modified and Willis-Mollay techniques are effective for detection particularly of Toxocara in dogs.Objetivou-se neste estudo avaliar a eficácia do pamoato pirantel e da ivermectina sobre nematódeos gastrointestinais de cães. Para tanto foram realizados a contagem de ovos nas fezes (OPG) para avaliação da eficiência anti-helmíntica através do Teste de Redução da Contagem de Ovos nas Fezes (RCOF) e exame de flutuação Willis-Mollay para verificação de concordância entre as técnicas coproparasitológicas. Selecionou-se 45 cães na cidade de Bandeirantes, Paraná, naturalmente infectados, os quais foram divididos em três grupos experimentais: Grupo 1, 15 animais que receberam pamoato de pirantel 145 mg; Grupo 2, 15 animais que receberam ivermectina 3 mg e Grupo 3, 15 animais do grupo controle, não tratados. Coletas de fezes foram realizadas dois e dez dias depois para realização dos exames coproparasitológicos. Observou-se que o gênero de maior prevalência foi Toxocara, seguido de Ancylostoma e Trichuris. Ancylostoma apresentou baixa resistência ao tratamento com pamoato de pirantel e ivermectina, e Toxocara foi resistente a ambos os tratamentos. Através de testes de concordância estatística entre as técnicas coproparasitológicas utilizadas, foram constatadas concordâncias moderada, quase perfeita e substancial, respectivamente, na detecção de Ancylostoma, Toxocara e Trichuris. Concluímos neste estudo que o gênero Ancylostoma apresentou baixa resistência e Toxocara é resistente à ambas as drogas e, devido às suas altas frequências em animais jovens, devem ser indicadas outras drogas anti-helmínticas para o combate destas parasitoses. Adicionalmente, as Técnicas de Gordon e Whitlock modificada e Willis-Mollay podem ser utilizadas para detecção principalmente de Toxocara em cães.UEL2015-12-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPesquisa Empírica de CampoPesquisa Empírica de Campoapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/1950910.5433/1679-0359.2015v36n6p3731Semina: Ciências Agrárias; Vol. 36 No. 6 (2015); 3731-3740Semina: Ciências Agrárias; v. 36 n. 6 (2015); 3731-37401679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELenghttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509/17513http://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessJesus, Ana PaulaHolsback, LucianeSelingardi, Maísa SantiagoCardoso, Mauro José LahmCabral, Luciana Doria RibeiroSantos, Tainá Rodrigues2022-12-05T11:38:14Zoai:ojs.pkp.sfu.ca:article/19509Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2022-12-05T11:38:14Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false |
dc.title.none.fl_str_mv |
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes Eficácia do pamoato de pirantel e da ivermectina no tratamento de nematódeos caninos |
title |
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes |
spellingShingle |
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes Jesus, Ana Paula Ancylostomiasis Dogs Parasitic resistance Toxocariasis. Ancilostomíase Cães Resistência parasitária Toxocaríase. |
title_short |
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes |
title_full |
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes |
title_fullStr |
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes |
title_full_unstemmed |
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes |
title_sort |
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes |
author |
Jesus, Ana Paula |
author_facet |
Jesus, Ana Paula Holsback, Luciane Selingardi, Maísa Santiago Cardoso, Mauro José Lahm Cabral, Luciana Doria Ribeiro Santos, Tainá Rodrigues |
author_role |
author |
author2 |
Holsback, Luciane Selingardi, Maísa Santiago Cardoso, Mauro José Lahm Cabral, Luciana Doria Ribeiro Santos, Tainá Rodrigues |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Jesus, Ana Paula Holsback, Luciane Selingardi, Maísa Santiago Cardoso, Mauro José Lahm Cabral, Luciana Doria Ribeiro Santos, Tainá Rodrigues |
dc.subject.por.fl_str_mv |
Ancylostomiasis Dogs Parasitic resistance Toxocariasis. Ancilostomíase Cães Resistência parasitária Toxocaríase. |
topic |
Ancylostomiasis Dogs Parasitic resistance Toxocariasis. Ancilostomíase Cães Resistência parasitária Toxocaríase. |
description |
This study evaluated the efficacy of pyrantel pamoate and ivermectin on gastrointestinal nematodes in dogs. Fecal egg counts per gram (EPG) were measured by the fecal egg count reduction test (FECRT) in order to evaluate the anthelmintic efficiency and fecal float exams were also performed to assess the concordance between coproparasitological techniques. A total of 45 naturally infected dogs in the city of Bandeirantes, Paraná State, were selected and divided into three groups: Group 1, 15 animals that received pyrantel pamoate (145 mg) in a single dose; Group 2, 15 animals that received ivermectin (3 mg); and Group 3, 15 animals that comprised an untreated control group. Fecal testing was performed two and 10 days after treatment. Toxocara was the most prevalent genus, followed by Ancylostoma and Trichuris. Ancylostoma had low resistance to ivermectin and pyrantel pamoate treatment, while Toxocara were resistant to both treatments. Statistical correlation testing to compare coproparasitogical techniques revealed moderate concordance, substantial and almost perfect concordance for detection of Ancylostoma, Trichuris, and Toxocara, respectively. The results of this study suggest that the gender Ancylostoma had low resistance and Toxocara is resistant to both drugs and because of their high prevalence in young animals means that others anthelmintic drugs may be recommended to combat infections. Additionally, the Gordon and Whitlock modified and Willis-Mollay techniques are effective for detection particularly of Toxocara in dogs. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-12-09 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Pesquisa Empírica de Campo Pesquisa Empírica de Campo |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509 10.5433/1679-0359.2015v36n6p3731 |
url |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509 |
identifier_str_mv |
10.5433/1679-0359.2015v36n6p3731 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509/17513 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UEL |
publisher.none.fl_str_mv |
UEL |
dc.source.none.fl_str_mv |
Semina: Ciências Agrárias; Vol. 36 No. 6 (2015); 3731-3740 Semina: Ciências Agrárias; v. 36 n. 6 (2015); 3731-3740 1679-0359 1676-546X reponame:Semina. Ciências Agrárias (Online) instname:Universidade Estadual de Londrina (UEL) instacron:UEL |
instname_str |
Universidade Estadual de Londrina (UEL) |
instacron_str |
UEL |
institution |
UEL |
reponame_str |
Semina. Ciências Agrárias (Online) |
collection |
Semina. Ciências Agrárias (Online) |
repository.name.fl_str_mv |
Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL) |
repository.mail.fl_str_mv |
semina.agrarias@uel.br |
_version_ |
1799306072749506560 |