Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes

Detalhes bibliográficos
Autor(a) principal: Jesus, Ana Paula
Data de Publicação: 2015
Outros Autores: Holsback, Luciane, Selingardi, Maísa Santiago, Cardoso, Mauro José Lahm, Cabral, Luciana Doria Ribeiro, Santos, Tainá Rodrigues
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509
Resumo: This study evaluated the efficacy of pyrantel pamoate and ivermectin on gastrointestinal nematodes in dogs. Fecal egg counts per gram (EPG) were measured by the fecal egg count reduction test (FECRT) in order to evaluate the anthelmintic efficiency and fecal float exams were also performed to assess the concordance between coproparasitological techniques. A total of 45 naturally infected dogs in the city of Bandeirantes, Paraná State, were selected and divided into three groups: Group 1, 15 animals that received pyrantel pamoate (145 mg) in a single dose; Group 2, 15 animals that received ivermectin (3 mg); and Group 3, 15 animals that comprised an untreated control group. Fecal testing was performed two and 10 days after treatment. Toxocara was the most prevalent genus, followed by Ancylostoma and Trichuris. Ancylostoma had low resistance to ivermectin and pyrantel pamoate treatment, while Toxocara were resistant to both treatments. Statistical correlation testing to compare coproparasitogical techniques revealed moderate concordance, substantial and almost perfect concordance for detection of Ancylostoma, Trichuris, and Toxocara, respectively. The results of this study suggest that the gender Ancylostoma had low resistance and Toxocara is resistant to both drugs and because of their high prevalence in young animals means that others anthelmintic drugs may be recommended to combat infections. Additionally, the Gordon and Whitlock modified and Willis-Mollay techniques are effective for detection particularly of Toxocara in dogs.
id UEL-11_2a9cafb1e5ff0fee5d3961078aff7db3
oai_identifier_str oai:ojs.pkp.sfu.ca:article/19509
network_acronym_str UEL-11
network_name_str Semina. Ciências Agrárias (Online)
repository_id_str
spelling Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodesEficácia do pamoato de pirantel e da ivermectina no tratamento de nematódeos caninosAncylostomiasisDogsParasitic resistanceToxocariasis.AncilostomíaseCãesResistência parasitáriaToxocaríase.This study evaluated the efficacy of pyrantel pamoate and ivermectin on gastrointestinal nematodes in dogs. Fecal egg counts per gram (EPG) were measured by the fecal egg count reduction test (FECRT) in order to evaluate the anthelmintic efficiency and fecal float exams were also performed to assess the concordance between coproparasitological techniques. A total of 45 naturally infected dogs in the city of Bandeirantes, Paraná State, were selected and divided into three groups: Group 1, 15 animals that received pyrantel pamoate (145 mg) in a single dose; Group 2, 15 animals that received ivermectin (3 mg); and Group 3, 15 animals that comprised an untreated control group. Fecal testing was performed two and 10 days after treatment. Toxocara was the most prevalent genus, followed by Ancylostoma and Trichuris. Ancylostoma had low resistance to ivermectin and pyrantel pamoate treatment, while Toxocara were resistant to both treatments. Statistical correlation testing to compare coproparasitogical techniques revealed moderate concordance, substantial and almost perfect concordance for detection of Ancylostoma, Trichuris, and Toxocara, respectively. The results of this study suggest that the gender Ancylostoma had low resistance and Toxocara is resistant to both drugs and because of their high prevalence in young animals means that others anthelmintic drugs may be recommended to combat infections. Additionally, the Gordon and Whitlock modified and Willis-Mollay techniques are effective for detection particularly of Toxocara in dogs.Objetivou-se neste estudo avaliar a eficácia do pamoato pirantel e da ivermectina sobre nematódeos gastrointestinais de cães. Para tanto foram realizados a contagem de ovos nas fezes (OPG) para avaliação da eficiência anti-helmíntica através do Teste de Redução da Contagem de Ovos nas Fezes (RCOF) e exame de flutuação Willis-Mollay para verificação de concordância entre as técnicas coproparasitológicas. Selecionou-se 45 cães na cidade de Bandeirantes, Paraná, naturalmente infectados, os quais foram divididos em três grupos experimentais: Grupo 1, 15 animais que receberam pamoato de pirantel 145 mg; Grupo 2, 15 animais que receberam ivermectina 3 mg e Grupo 3, 15 animais do grupo controle, não tratados. Coletas de fezes foram realizadas dois e dez dias depois para realização dos exames coproparasitológicos. Observou-se que o gênero de maior prevalência foi Toxocara, seguido de Ancylostoma e Trichuris. Ancylostoma apresentou baixa resistência ao tratamento com pamoato de pirantel e ivermectina, e Toxocara foi resistente a ambos os tratamentos. Através de testes de concordância estatística entre as técnicas coproparasitológicas utilizadas, foram constatadas concordâncias moderada, quase perfeita e substancial, respectivamente, na detecção de Ancylostoma, Toxocara e Trichuris. Concluímos neste estudo que o gênero Ancylostoma apresentou baixa resistência e Toxocara é resistente à ambas as drogas e, devido às suas altas frequências em animais jovens, devem ser indicadas outras drogas anti-helmínticas para o combate destas parasitoses. Adicionalmente, as Técnicas de Gordon e Whitlock modificada e Willis-Mollay podem ser utilizadas para detecção principalmente de Toxocara em cães.UEL2015-12-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPesquisa Empírica de CampoPesquisa Empírica de Campoapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/1950910.5433/1679-0359.2015v36n6p3731Semina: Ciências Agrárias; Vol. 36 No. 6 (2015); 3731-3740Semina: Ciências Agrárias; v. 36 n. 6 (2015); 3731-37401679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELenghttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509/17513http://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessJesus, Ana PaulaHolsback, LucianeSelingardi, Maísa SantiagoCardoso, Mauro José LahmCabral, Luciana Doria RibeiroSantos, Tainá Rodrigues2022-12-05T11:38:14Zoai:ojs.pkp.sfu.ca:article/19509Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2022-12-05T11:38:14Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
Eficácia do pamoato de pirantel e da ivermectina no tratamento de nematódeos caninos
title Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
spellingShingle Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
Jesus, Ana Paula
Ancylostomiasis
Dogs
Parasitic resistance
Toxocariasis.
Ancilostomíase
Cães
Resistência parasitária
Toxocaríase.
title_short Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
title_full Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
title_fullStr Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
title_full_unstemmed Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
title_sort Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes
author Jesus, Ana Paula
author_facet Jesus, Ana Paula
Holsback, Luciane
Selingardi, Maísa Santiago
Cardoso, Mauro José Lahm
Cabral, Luciana Doria Ribeiro
Santos, Tainá Rodrigues
author_role author
author2 Holsback, Luciane
Selingardi, Maísa Santiago
Cardoso, Mauro José Lahm
Cabral, Luciana Doria Ribeiro
Santos, Tainá Rodrigues
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Jesus, Ana Paula
Holsback, Luciane
Selingardi, Maísa Santiago
Cardoso, Mauro José Lahm
Cabral, Luciana Doria Ribeiro
Santos, Tainá Rodrigues
dc.subject.por.fl_str_mv Ancylostomiasis
Dogs
Parasitic resistance
Toxocariasis.
Ancilostomíase
Cães
Resistência parasitária
Toxocaríase.
topic Ancylostomiasis
Dogs
Parasitic resistance
Toxocariasis.
Ancilostomíase
Cães
Resistência parasitária
Toxocaríase.
description This study evaluated the efficacy of pyrantel pamoate and ivermectin on gastrointestinal nematodes in dogs. Fecal egg counts per gram (EPG) were measured by the fecal egg count reduction test (FECRT) in order to evaluate the anthelmintic efficiency and fecal float exams were also performed to assess the concordance between coproparasitological techniques. A total of 45 naturally infected dogs in the city of Bandeirantes, Paraná State, were selected and divided into three groups: Group 1, 15 animals that received pyrantel pamoate (145 mg) in a single dose; Group 2, 15 animals that received ivermectin (3 mg); and Group 3, 15 animals that comprised an untreated control group. Fecal testing was performed two and 10 days after treatment. Toxocara was the most prevalent genus, followed by Ancylostoma and Trichuris. Ancylostoma had low resistance to ivermectin and pyrantel pamoate treatment, while Toxocara were resistant to both treatments. Statistical correlation testing to compare coproparasitogical techniques revealed moderate concordance, substantial and almost perfect concordance for detection of Ancylostoma, Trichuris, and Toxocara, respectively. The results of this study suggest that the gender Ancylostoma had low resistance and Toxocara is resistant to both drugs and because of their high prevalence in young animals means that others anthelmintic drugs may be recommended to combat infections. Additionally, the Gordon and Whitlock modified and Willis-Mollay techniques are effective for detection particularly of Toxocara in dogs.
publishDate 2015
dc.date.none.fl_str_mv 2015-12-09
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Pesquisa Empírica de Campo
Pesquisa Empírica de Campo
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509
10.5433/1679-0359.2015v36n6p3731
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509
identifier_str_mv 10.5433/1679-0359.2015v36n6p3731
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/19509/17513
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 36 No. 6 (2015); 3731-3740
Semina: Ciências Agrárias; v. 36 n. 6 (2015); 3731-3740
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
_version_ 1799306072749506560