Brucella ovis: invasion, traffic, virulence factors and immune response
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Semina. Ciências Agrárias (Online) |
Texto Completo: | https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582 |
Resumo: | Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent in these locations are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection. |
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Semina. Ciências Agrárias (Online) |
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Brucella ovis: invasion, traffic, virulence factors and immune responseBrucella ovis: invasão, tráfego, fatores de virulência e resposta imuneBrucellosisPathogenesisImmunopathologyBrucella ovis.BrucelosePatogeniaImunopatologiaBrucella ovis.5.05.02.03-4 Doenças Infecciosas de AnimaisBrucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent in these locations are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.A brucelose permanece como problema econômico em animais e de saúde pública. Em todo o mundo a brucelose ovina ocasionada pela Brucella ovis é considerada uma das principais causas de infertilidade em ovinos. Os fatores responsáveis pela persistência do agente nestes locais não são conhecidos, bem como os mecanismos imunes envolvidos na defesa e eventualmente na persistência do agente. Brucella spp. induz resposta inflamatória moderada. A natureza intracelular do agente estimula resposta imune celular do tipo linfócito T helper 1. Os estudos de patogenia da brucelose ovina são escassos. Recentes avanços demonstraram que a resposta inflamatória moderada induzida pelas brucelas representam provavelmente o resultado de tentativa de escape da resposta imune e supressão da resposta imune hospedeira. Foram revisados os mecanismos descritos pelas brucelas e pela Brucella ovis para penetração no hospedeiro, escape da resposta imune, bem como a resposta imunológica gerada pela infecção.UEL2013-06-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de Literaturaapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/1258210.5433/1679-0359.2013v34n3p1301Semina: Ciências Agrárias; Vol. 34 No. 3 (2013); 1301-1312Semina: Ciências Agrárias; v. 34 n. 3 (2013); 1301-13121679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582/pdfCopyright (c) 2013 Semina: Ciências Agráriashttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessAntunes, João Marcelo Azevedo de PaulaMegid, Jane2023-01-17T12:11:25Zoai:ojs.pkp.sfu.ca:article/12582Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2023-01-17T12:11:25Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false |
dc.title.none.fl_str_mv |
Brucella ovis: invasion, traffic, virulence factors and immune response Brucella ovis: invasão, tráfego, fatores de virulência e resposta imune |
title |
Brucella ovis: invasion, traffic, virulence factors and immune response |
spellingShingle |
Brucella ovis: invasion, traffic, virulence factors and immune response Antunes, João Marcelo Azevedo de Paula Brucellosis Pathogenesis Immunopathology Brucella ovis. Brucelose Patogenia Imunopatologia Brucella ovis. 5.05.02.03-4 Doenças Infecciosas de Animais |
title_short |
Brucella ovis: invasion, traffic, virulence factors and immune response |
title_full |
Brucella ovis: invasion, traffic, virulence factors and immune response |
title_fullStr |
Brucella ovis: invasion, traffic, virulence factors and immune response |
title_full_unstemmed |
Brucella ovis: invasion, traffic, virulence factors and immune response |
title_sort |
Brucella ovis: invasion, traffic, virulence factors and immune response |
author |
Antunes, João Marcelo Azevedo de Paula |
author_facet |
Antunes, João Marcelo Azevedo de Paula Megid, Jane |
author_role |
author |
author2 |
Megid, Jane |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Antunes, João Marcelo Azevedo de Paula Megid, Jane |
dc.subject.por.fl_str_mv |
Brucellosis Pathogenesis Immunopathology Brucella ovis. Brucelose Patogenia Imunopatologia Brucella ovis. 5.05.02.03-4 Doenças Infecciosas de Animais |
topic |
Brucellosis Pathogenesis Immunopathology Brucella ovis. Brucelose Patogenia Imunopatologia Brucella ovis. 5.05.02.03-4 Doenças Infecciosas de Animais |
description |
Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent in these locations are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-06-24 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Revisão de Literatura |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582 10.5433/1679-0359.2013v34n3p1301 |
url |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582 |
identifier_str_mv |
10.5433/1679-0359.2013v34n3p1301 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582/pdf |
dc.rights.driver.fl_str_mv |
Copyright (c) 2013 Semina: Ciências Agrárias http://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2013 Semina: Ciências Agrárias http://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UEL |
publisher.none.fl_str_mv |
UEL |
dc.source.none.fl_str_mv |
Semina: Ciências Agrárias; Vol. 34 No. 3 (2013); 1301-1312 Semina: Ciências Agrárias; v. 34 n. 3 (2013); 1301-1312 1679-0359 1676-546X reponame:Semina. Ciências Agrárias (Online) instname:Universidade Estadual de Londrina (UEL) instacron:UEL |
instname_str |
Universidade Estadual de Londrina (UEL) |
instacron_str |
UEL |
institution |
UEL |
reponame_str |
Semina. Ciências Agrárias (Online) |
collection |
Semina. Ciências Agrárias (Online) |
repository.name.fl_str_mv |
Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL) |
repository.mail.fl_str_mv |
semina.agrarias@uel.br |
_version_ |
1799306067764576256 |