Brucella ovis: invasion, traffic, virulence factors and immune response

Detalhes bibliográficos
Autor(a) principal: Antunes, João Marcelo Azevedo de Paula
Data de Publicação: 2013
Outros Autores: Megid, Jane
Tipo de documento: Artigo
Idioma: por
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582
Resumo: Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent in these locations are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.
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spelling Brucella ovis: invasion, traffic, virulence factors and immune responseBrucella ovis: invasão, tráfego, fatores de virulência e resposta imuneBrucellosisPathogenesisImmunopathologyBrucella ovis.BrucelosePatogeniaImunopatologiaBrucella ovis.5.05.02.03-4 Doenças Infecciosas de AnimaisBrucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent in these locations are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.A brucelose permanece como problema econômico em animais e de saúde pública. Em todo o mundo a brucelose ovina ocasionada pela Brucella ovis é considerada uma das principais causas de infertilidade em ovinos. Os fatores responsáveis pela persistência do agente nestes locais não são conhecidos, bem como os mecanismos imunes envolvidos na defesa e eventualmente na persistência do agente. Brucella spp. induz resposta inflamatória moderada. A natureza intracelular do agente estimula resposta imune celular do tipo linfócito T helper 1. Os estudos de patogenia da brucelose ovina são escassos. Recentes avanços demonstraram que a resposta inflamatória moderada induzida pelas brucelas representam provavelmente o resultado de tentativa de escape da resposta imune e supressão da resposta imune hospedeira. Foram revisados os mecanismos descritos pelas brucelas e pela Brucella ovis para penetração no hospedeiro, escape da resposta imune, bem como a resposta imunológica gerada pela infecção.UEL2013-06-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de Literaturaapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/1258210.5433/1679-0359.2013v34n3p1301Semina: Ciências Agrárias; Vol. 34 No. 3 (2013); 1301-1312Semina: Ciências Agrárias; v. 34 n. 3 (2013); 1301-13121679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582/pdfCopyright (c) 2013 Semina: Ciências Agráriashttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessAntunes, João Marcelo Azevedo de PaulaMegid, Jane2023-01-17T12:11:25Zoai:ojs.pkp.sfu.ca:article/12582Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2023-01-17T12:11:25Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Brucella ovis: invasion, traffic, virulence factors and immune response
Brucella ovis: invasão, tráfego, fatores de virulência e resposta imune
title Brucella ovis: invasion, traffic, virulence factors and immune response
spellingShingle Brucella ovis: invasion, traffic, virulence factors and immune response
Antunes, João Marcelo Azevedo de Paula
Brucellosis
Pathogenesis
Immunopathology
Brucella ovis.
Brucelose
Patogenia
Imunopatologia
Brucella ovis.
5.05.02.03-4 Doenças Infecciosas de Animais
title_short Brucella ovis: invasion, traffic, virulence factors and immune response
title_full Brucella ovis: invasion, traffic, virulence factors and immune response
title_fullStr Brucella ovis: invasion, traffic, virulence factors and immune response
title_full_unstemmed Brucella ovis: invasion, traffic, virulence factors and immune response
title_sort Brucella ovis: invasion, traffic, virulence factors and immune response
author Antunes, João Marcelo Azevedo de Paula
author_facet Antunes, João Marcelo Azevedo de Paula
Megid, Jane
author_role author
author2 Megid, Jane
author2_role author
dc.contributor.author.fl_str_mv Antunes, João Marcelo Azevedo de Paula
Megid, Jane
dc.subject.por.fl_str_mv Brucellosis
Pathogenesis
Immunopathology
Brucella ovis.
Brucelose
Patogenia
Imunopatologia
Brucella ovis.
5.05.02.03-4 Doenças Infecciosas de Animais
topic Brucellosis
Pathogenesis
Immunopathology
Brucella ovis.
Brucelose
Patogenia
Imunopatologia
Brucella ovis.
5.05.02.03-4 Doenças Infecciosas de Animais
description Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent in these locations are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.
publishDate 2013
dc.date.none.fl_str_mv 2013-06-24
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Revisão de Literatura
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582
10.5433/1679-0359.2013v34n3p1301
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582
identifier_str_mv 10.5433/1679-0359.2013v34n3p1301
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/12582/pdf
dc.rights.driver.fl_str_mv Copyright (c) 2013 Semina: Ciências Agrárias
http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2013 Semina: Ciências Agrárias
http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 34 No. 3 (2013); 1301-1312
Semina: Ciências Agrárias; v. 34 n. 3 (2013); 1301-1312
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
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