Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune

Detalhes bibliográficos
Autor(a) principal: De Paula Antunes, João Marcelo Azevedo [UNESP]
Data de Publicação: 2013
Outros Autores: Megid, Jane [UNESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.5433/1679-0359.2013v34n3p1301
http://hdl.handle.net/11449/75322
Resumo: Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.
id UNSP_df85f082a3cf8319272060663409226e
oai_identifier_str oai:repositorio.unesp.br:11449/75322
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imuneBrucella ovis: Invasion, traffic, virulence factors and immune responseBrucella ovisBrucellosisImmunopathologyPathogenesisBrucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.Faculdade de Medicina Veterinária e Zootecnia FMVZ Universidade Estadual Paulista, UNESP, Botucatu, SPFMVZ/UNESP, Botucatu, SPFaculdade de Medicina Veterinária e Zootecnia FMVZ Universidade Estadual Paulista, UNESP, Botucatu, SPFMVZ/UNESP, Botucatu, SPUniversidade Estadual Paulista (Unesp)De Paula Antunes, João Marcelo Azevedo [UNESP]Megid, Jane [UNESP]2014-05-27T11:29:05Z2014-05-27T11:29:05Z2013-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1301-1312application/pdfhttp://dx.doi.org/10.5433/1679-0359.2013v34n3p1301Semina:Ciencias Agrarias, v. 34, n. 3, p. 1301-1312, 2013.1676-546X1679-0359http://hdl.handle.net/11449/7532210.5433/1679-0359.2013v34n3p1301WOS:0003282679000352-s2.0-848801920092-s2.0-84880192009.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporSemina: Ciências Agrárias0.3490,320info:eu-repo/semantics/openAccess2023-12-07T06:19:51Zoai:repositorio.unesp.br:11449/75322Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:43:59.317472Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
Brucella ovis: Invasion, traffic, virulence factors and immune response
title Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
spellingShingle Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
De Paula Antunes, João Marcelo Azevedo [UNESP]
Brucella ovis
Brucellosis
Immunopathology
Pathogenesis
title_short Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
title_full Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
title_fullStr Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
title_full_unstemmed Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
title_sort Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
author De Paula Antunes, João Marcelo Azevedo [UNESP]
author_facet De Paula Antunes, João Marcelo Azevedo [UNESP]
Megid, Jane [UNESP]
author_role author
author2 Megid, Jane [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv De Paula Antunes, João Marcelo Azevedo [UNESP]
Megid, Jane [UNESP]
dc.subject.por.fl_str_mv Brucella ovis
Brucellosis
Immunopathology
Pathogenesis
topic Brucella ovis
Brucellosis
Immunopathology
Pathogenesis
description Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.
publishDate 2013
dc.date.none.fl_str_mv 2013-05-01
2014-05-27T11:29:05Z
2014-05-27T11:29:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.5433/1679-0359.2013v34n3p1301
Semina:Ciencias Agrarias, v. 34, n. 3, p. 1301-1312, 2013.
1676-546X
1679-0359
http://hdl.handle.net/11449/75322
10.5433/1679-0359.2013v34n3p1301
WOS:000328267900035
2-s2.0-84880192009
2-s2.0-84880192009.pdf
url http://dx.doi.org/10.5433/1679-0359.2013v34n3p1301
http://hdl.handle.net/11449/75322
identifier_str_mv Semina:Ciencias Agrarias, v. 34, n. 3, p. 1301-1312, 2013.
1676-546X
1679-0359
10.5433/1679-0359.2013v34n3p1301
WOS:000328267900035
2-s2.0-84880192009
2-s2.0-84880192009.pdf
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Semina: Ciências Agrárias
0.349
0,320
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1301-1312
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129110250094592