Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.5433/1679-0359.2013v34n3p1301 http://hdl.handle.net/11449/75322 |
Resumo: | Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection. |
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Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imuneBrucella ovis: Invasion, traffic, virulence factors and immune responseBrucella ovisBrucellosisImmunopathologyPathogenesisBrucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection.Faculdade de Medicina Veterinária e Zootecnia FMVZ Universidade Estadual Paulista, UNESP, Botucatu, SPFMVZ/UNESP, Botucatu, SPFaculdade de Medicina Veterinária e Zootecnia FMVZ Universidade Estadual Paulista, UNESP, Botucatu, SPFMVZ/UNESP, Botucatu, SPUniversidade Estadual Paulista (Unesp)De Paula Antunes, João Marcelo Azevedo [UNESP]Megid, Jane [UNESP]2014-05-27T11:29:05Z2014-05-27T11:29:05Z2013-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1301-1312application/pdfhttp://dx.doi.org/10.5433/1679-0359.2013v34n3p1301Semina:Ciencias Agrarias, v. 34, n. 3, p. 1301-1312, 2013.1676-546X1679-0359http://hdl.handle.net/11449/7532210.5433/1679-0359.2013v34n3p1301WOS:0003282679000352-s2.0-848801920092-s2.0-84880192009.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporSemina: Ciências Agrárias0.3490,320info:eu-repo/semantics/openAccess2023-12-07T06:19:51Zoai:repositorio.unesp.br:11449/75322Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:43:59.317472Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune Brucella ovis: Invasion, traffic, virulence factors and immune response |
title |
Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune |
spellingShingle |
Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune De Paula Antunes, João Marcelo Azevedo [UNESP] Brucella ovis Brucellosis Immunopathology Pathogenesis |
title_short |
Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune |
title_full |
Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune |
title_fullStr |
Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune |
title_full_unstemmed |
Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune |
title_sort |
Brucella ovis: InvasãO, tráfego, fatores de virulência e resposta imune |
author |
De Paula Antunes, João Marcelo Azevedo [UNESP] |
author_facet |
De Paula Antunes, João Marcelo Azevedo [UNESP] Megid, Jane [UNESP] |
author_role |
author |
author2 |
Megid, Jane [UNESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
De Paula Antunes, João Marcelo Azevedo [UNESP] Megid, Jane [UNESP] |
dc.subject.por.fl_str_mv |
Brucella ovis Brucellosis Immunopathology Pathogenesis |
topic |
Brucella ovis Brucellosis Immunopathology Pathogenesis |
description |
Brucellosis remains an economic problem in animals and public health. Worldwide ovine brucellosis caused by Brucella ovis is considered a major cause of infertility in sheep. The factors responsible for persistence of the agent are not known, as well as the mechanisms involved in immune defense and possibly the persistence of the agent. Brucella spp. induces moderate inflammatory response. The nature of the intracellular agent stimulates immune response of the type 1 helper T lymphocytes. Studies of the pathogenesis of ovine brucellosis are scarce. Recent developments have shown that the inflammatory response induced by moderate brucelas represent probably the result of an attempt to escape the immune response and suppression of host immune response. Were reviewed by the mechanisms described by brucelas and Brucella ovis for penetration into the host, escape of the immune response and the immune response generated by the infection. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-05-01 2014-05-27T11:29:05Z 2014-05-27T11:29:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.5433/1679-0359.2013v34n3p1301 Semina:Ciencias Agrarias, v. 34, n. 3, p. 1301-1312, 2013. 1676-546X 1679-0359 http://hdl.handle.net/11449/75322 10.5433/1679-0359.2013v34n3p1301 WOS:000328267900035 2-s2.0-84880192009 2-s2.0-84880192009.pdf |
url |
http://dx.doi.org/10.5433/1679-0359.2013v34n3p1301 http://hdl.handle.net/11449/75322 |
identifier_str_mv |
Semina:Ciencias Agrarias, v. 34, n. 3, p. 1301-1312, 2013. 1676-546X 1679-0359 10.5433/1679-0359.2013v34n3p1301 WOS:000328267900035 2-s2.0-84880192009 2-s2.0-84880192009.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Semina: Ciências Agrárias 0.349 0,320 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1301-1312 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129110250094592 |