Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats

Detalhes bibliográficos
Autor(a) principal: Silva, Aleksandro Schafer
Data de Publicação: 2010
Outros Autores: Wolkmer, Patrícia, Costa, Márcio Machado, Faccio, Luciana, Soares, André Vasconcelos, Garcia, Érika Fernanda, Lopes, Sonia Terezinha dos Anjos, Santurio, Janio Morais, Monteiro, Silvia Gonzalez
Tipo de documento: Artigo
Idioma: por
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/6515
Resumo: Trypanosoma evansi is a protozoan which causes trypanosomosis in livestock in many countries of Southeast Asia, Africa and South America. We chose to use cats in our study due to the facility to handle the animals and the lack of studies involving the trypanosomosis in this species. The aim of this study was to analyze the leukogram of domestic cats experimentally infected with T. evansi and its correlation to the parasitemia. Thirteen animals were divided into two groups. Seven animals were infected with T. evansi and six were used as negative control. Parasitemia was estimated daily by microscopic examination of smears. Blood samples for leukogram were collected at days 0, 7, 21, 35 and 49. The parasitemia peak was recorded at day five post-inoculation. Thereafter, irregular waves of parasitemia were observed, ranging from zero to three trypomastigotes per microscopic field. Increased number of total leukocytes (day 49), monocytes (days 7, 35 and 49), segmented (day 49) and nonsegmented neuthrophils (day 35), and decreased number of lymphocytes and eosinophils (days 21, 35 and 49) were observed (P < 0.05). Cats infected with T. evansi have leukocytosis, neutrophilia, monocytosis, lymphopenia and eosinopenia. However, no relationship between parasitemia peaks and white blood cells was observed, except by the monocytes in day 7.
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spelling Relationship between parasitemia and leukogram in Trypanosoma evansi infected catsRelação parasitemia e leucograma de gatos infectados com Trypanosoma evansiTrypanosomosisFelinesImmunological systemParasitismTripanossomoseFelinosSistema imunológicoParasitismoTrypanosoma evansi is a protozoan which causes trypanosomosis in livestock in many countries of Southeast Asia, Africa and South America. We chose to use cats in our study due to the facility to handle the animals and the lack of studies involving the trypanosomosis in this species. The aim of this study was to analyze the leukogram of domestic cats experimentally infected with T. evansi and its correlation to the parasitemia. Thirteen animals were divided into two groups. Seven animals were infected with T. evansi and six were used as negative control. Parasitemia was estimated daily by microscopic examination of smears. Blood samples for leukogram were collected at days 0, 7, 21, 35 and 49. The parasitemia peak was recorded at day five post-inoculation. Thereafter, irregular waves of parasitemia were observed, ranging from zero to three trypomastigotes per microscopic field. Increased number of total leukocytes (day 49), monocytes (days 7, 35 and 49), segmented (day 49) and nonsegmented neuthrophils (day 35), and decreased number of lymphocytes and eosinophils (days 21, 35 and 49) were observed (P < 0.05). Cats infected with T. evansi have leukocytosis, neutrophilia, monocytosis, lymphopenia and eosinopenia. However, no relationship between parasitemia peaks and white blood cells was observed, except by the monocytes in day 7. Trypanosoma evansi é um protozoário que causa a tripanossomose em animais de muitos países do sudeste da Ásia, África e América do Sul. Optamos por utilizar os gatos em nosso estudo, devido à facilidade de manipular os animais e a falta de estudos envolvendo a tripanossomose nesta espécie. Deste modo, o objetivo deste estudo foi investigar alterações no leucograma de felinos domésticos infectados experimentalmente por T. evansi e relacionar com a parasitemia. Foram utilizados 13 gatos, divididos em dois grupos. Sete deles foram infectados com T. evansi e o restante foram utilizados como grupo controle negativo. Os animais foram monitorados diariamente através de esfregaço sanguíneo. Nos dias 0, 7, 21, 35 e 49 de experimento, foram coletadas amostras de sangue para avaliação do leucograma. O pico de parasitemia ocorreu cinco dias após inoculação, após este período o número de parasitos reduziu e manteve-se com picos irregulares, variando de zero a três tripomastigotas/campo. Na pesquisa foi verificado aumento (P < 0,05) do número de leucócitos totais (dia 49), bastonetes (dia 35), neutrofilos segmentados (dia 49) e monócitos (dias 7, 35 e 49) e redução de linfocitos e eosinofilos (dias 21, 35 e 49). Gatos infectados com T. evansi apresentam leucocitose, neutrofilia, monocitose, linfopenia e eosinopenia. Porém, não foi verificado relação entre os picos de parasitemia e alteração no número de globulos brancos circulantes, com execção dos monócitos no dia 7. UEL2010-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/651510.5433/1679-0359.2010v31n3p699Semina: Ciências Agrárias; Vol. 31 No. 3 (2010); 699-706Semina: Ciências Agrárias; v. 31 n. 3 (2010); 699-7061679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/6515/5915Silva, Aleksandro SchaferWolkmer, PatríciaCosta, Márcio MachadoFaccio, LucianaSoares, André VasconcelosGarcia, Érika FernandaLopes, Sonia Terezinha dos AnjosSanturio, Janio MoraisMonteiro, Silvia Gonzalezinfo:eu-repo/semantics/openAccess2015-11-19T18:38:21Zoai:ojs.pkp.sfu.ca:article/6515Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2015-11-19T18:38:21Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats
Relação parasitemia e leucograma de gatos infectados com Trypanosoma evansi
title Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats
spellingShingle Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats
Silva, Aleksandro Schafer
Trypanosomosis
Felines
Immunological system
Parasitism
Tripanossomose
Felinos
Sistema imunológico
Parasitismo
title_short Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats
title_full Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats
title_fullStr Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats
title_full_unstemmed Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats
title_sort Relationship between parasitemia and leukogram in Trypanosoma evansi infected cats
author Silva, Aleksandro Schafer
author_facet Silva, Aleksandro Schafer
Wolkmer, Patrícia
Costa, Márcio Machado
Faccio, Luciana
Soares, André Vasconcelos
Garcia, Érika Fernanda
Lopes, Sonia Terezinha dos Anjos
Santurio, Janio Morais
Monteiro, Silvia Gonzalez
author_role author
author2 Wolkmer, Patrícia
Costa, Márcio Machado
Faccio, Luciana
Soares, André Vasconcelos
Garcia, Érika Fernanda
Lopes, Sonia Terezinha dos Anjos
Santurio, Janio Morais
Monteiro, Silvia Gonzalez
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Aleksandro Schafer
Wolkmer, Patrícia
Costa, Márcio Machado
Faccio, Luciana
Soares, André Vasconcelos
Garcia, Érika Fernanda
Lopes, Sonia Terezinha dos Anjos
Santurio, Janio Morais
Monteiro, Silvia Gonzalez
dc.subject.por.fl_str_mv Trypanosomosis
Felines
Immunological system
Parasitism
Tripanossomose
Felinos
Sistema imunológico
Parasitismo
topic Trypanosomosis
Felines
Immunological system
Parasitism
Tripanossomose
Felinos
Sistema imunológico
Parasitismo
description Trypanosoma evansi is a protozoan which causes trypanosomosis in livestock in many countries of Southeast Asia, Africa and South America. We chose to use cats in our study due to the facility to handle the animals and the lack of studies involving the trypanosomosis in this species. The aim of this study was to analyze the leukogram of domestic cats experimentally infected with T. evansi and its correlation to the parasitemia. Thirteen animals were divided into two groups. Seven animals were infected with T. evansi and six were used as negative control. Parasitemia was estimated daily by microscopic examination of smears. Blood samples for leukogram were collected at days 0, 7, 21, 35 and 49. The parasitemia peak was recorded at day five post-inoculation. Thereafter, irregular waves of parasitemia were observed, ranging from zero to three trypomastigotes per microscopic field. Increased number of total leukocytes (day 49), monocytes (days 7, 35 and 49), segmented (day 49) and nonsegmented neuthrophils (day 35), and decreased number of lymphocytes and eosinophils (days 21, 35 and 49) were observed (P < 0.05). Cats infected with T. evansi have leukocytosis, neutrophilia, monocytosis, lymphopenia and eosinopenia. However, no relationship between parasitemia peaks and white blood cells was observed, except by the monocytes in day 7.
publishDate 2010
dc.date.none.fl_str_mv 2010-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/6515
10.5433/1679-0359.2010v31n3p699
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/6515
identifier_str_mv 10.5433/1679-0359.2010v31n3p699
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/6515/5915
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 31 No. 3 (2010); 699-706
Semina: Ciências Agrárias; v. 31 n. 3 (2010); 699-706
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
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reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
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