Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Semina. Ciências Agrárias (Online) |
Texto Completo: | https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/40310 |
Resumo: | Considering the importance of Haemonchus contortus infection in herds along with parasitic resistance, the goal of this study was to evaluate the influence of the administration of adjuvants alone or in combination with anthelmintics for the treatment of H. contortus, in experimentally infected sheep. Thirty sheep of the Texel breed of both genders, raised in a herd located in the subtropical region of Brazil, were used in this experiment. Experimental infection with H. contortus was performed in sheep, and the infected sheep were then separated into groups for the administration of antiparasitic and immunostimulant drugs. The results obtained from the excretion of eggs per gram of feces and the count of parasites during necropsy affirm that the use of adjuvants in combination with anthelmintics is associated with higher efficacy of treatment, lower rate of reinfection, and retardation in the development of anthelmintic drug resistance by H. contortus. Based on these results, we can conclude that the combination of anthelmintics and immunostimulants may favor potential anthelmintic treatments for H. contortus. |
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Semina. Ciências Agrárias (Online) |
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Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortusAssociação de imunoestimulantes com anti-helmínticos no tratamento de animais experimentalmente infectados com Haemonchus contortusInfectionTreatmentAdjuvantsAnthelmintics.InfecçãoTratamentoAdjuvantesAnti-helmínticos.Considering the importance of Haemonchus contortus infection in herds along with parasitic resistance, the goal of this study was to evaluate the influence of the administration of adjuvants alone or in combination with anthelmintics for the treatment of H. contortus, in experimentally infected sheep. Thirty sheep of the Texel breed of both genders, raised in a herd located in the subtropical region of Brazil, were used in this experiment. Experimental infection with H. contortus was performed in sheep, and the infected sheep were then separated into groups for the administration of antiparasitic and immunostimulant drugs. The results obtained from the excretion of eggs per gram of feces and the count of parasites during necropsy affirm that the use of adjuvants in combination with anthelmintics is associated with higher efficacy of treatment, lower rate of reinfection, and retardation in the development of anthelmintic drug resistance by H. contortus. Based on these results, we can conclude that the combination of anthelmintics and immunostimulants may favor potential anthelmintic treatments for H. contortus.Considerando a importância da infecção por Haemonchus contortus em rebanhos juntamente com a resistência parasitária, o objetivo deste estudo foi avaliar a influência da administração de adjuvantes isolados ou em combinação com o tratamento anti-helmíntico no tratamento de H. contortus em ovinos infectados experimentalmente. Foram utilizados trinta ovinos da raça Texel, de ambos os sexos criados em um rebanho localizado na região subtropical do Brasil, foram utilizados no experimento. A infecção experimental por H. contortus foi realizada em ovinos, separados em grupos para administração de medicamentos antiparasitários e imunoestimulantes. Os resultados obtidos da excreção de ovos por grama de fezes e da contagem de parasitas durante a necropsia afirmam que o uso de adjuvantes em combinação com anti-helmínticos está associado a maior eficácia do tratamento, menor taxa de reinfecção e retardo do processo de desenvolvimento de resistência anti-helmíntica por H. contortus. Com base nesses resultados, podemos concluir que a combinação de anti-helmínticos e imunoestimulantes podem favorecer potenciais tratamentos anti-helmínticos para H. contortus.UEL2021-02-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/4031010.5433/1679-0359.2021v42n2p707Semina: Ciências Agrárias; Vol. 42 No. 2 (2021); 707-720Semina: Ciências Agrárias; v. 42 n. 2 (2021); 707-7201679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELenghttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/40310/29030Copyright (c) 2021 Semina: Ciências Agráriashttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessPortella, Luiza PiresFernandes, Fagner D'ambrosoSangioni, Luís AntônioRamos, FernandaRodrigues, Fernando de SouzaMenezes, Fernanda Rezer deCezar, Alfredo SkrebskyFaccin, Tatiane CargninKommers, Glaucia DeniseVogel, Fernanda Silveira Flores2022-10-04T14:03:55Zoai:ojs.pkp.sfu.ca:article/40310Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2022-10-04T14:03:55Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false |
dc.title.none.fl_str_mv |
Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus Associação de imunoestimulantes com anti-helmínticos no tratamento de animais experimentalmente infectados com Haemonchus contortus |
title |
Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus |
spellingShingle |
Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus Portella, Luiza Pires Infection Treatment Adjuvants Anthelmintics. Infecção Tratamento Adjuvantes Anti-helmínticos. |
title_short |
Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus |
title_full |
Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus |
title_fullStr |
Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus |
title_full_unstemmed |
Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus |
title_sort |
Combination of immunostimulants with moxidectin in the treatment of animals experimentally infected with Haemonchus contortus |
author |
Portella, Luiza Pires |
author_facet |
Portella, Luiza Pires Fernandes, Fagner D'ambroso Sangioni, Luís Antônio Ramos, Fernanda Rodrigues, Fernando de Souza Menezes, Fernanda Rezer de Cezar, Alfredo Skrebsky Faccin, Tatiane Cargnin Kommers, Glaucia Denise Vogel, Fernanda Silveira Flores |
author_role |
author |
author2 |
Fernandes, Fagner D'ambroso Sangioni, Luís Antônio Ramos, Fernanda Rodrigues, Fernando de Souza Menezes, Fernanda Rezer de Cezar, Alfredo Skrebsky Faccin, Tatiane Cargnin Kommers, Glaucia Denise Vogel, Fernanda Silveira Flores |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Portella, Luiza Pires Fernandes, Fagner D'ambroso Sangioni, Luís Antônio Ramos, Fernanda Rodrigues, Fernando de Souza Menezes, Fernanda Rezer de Cezar, Alfredo Skrebsky Faccin, Tatiane Cargnin Kommers, Glaucia Denise Vogel, Fernanda Silveira Flores |
dc.subject.por.fl_str_mv |
Infection Treatment Adjuvants Anthelmintics. Infecção Tratamento Adjuvantes Anti-helmínticos. |
topic |
Infection Treatment Adjuvants Anthelmintics. Infecção Tratamento Adjuvantes Anti-helmínticos. |
description |
Considering the importance of Haemonchus contortus infection in herds along with parasitic resistance, the goal of this study was to evaluate the influence of the administration of adjuvants alone or in combination with anthelmintics for the treatment of H. contortus, in experimentally infected sheep. Thirty sheep of the Texel breed of both genders, raised in a herd located in the subtropical region of Brazil, were used in this experiment. Experimental infection with H. contortus was performed in sheep, and the infected sheep were then separated into groups for the administration of antiparasitic and immunostimulant drugs. The results obtained from the excretion of eggs per gram of feces and the count of parasites during necropsy affirm that the use of adjuvants in combination with anthelmintics is associated with higher efficacy of treatment, lower rate of reinfection, and retardation in the development of anthelmintic drug resistance by H. contortus. Based on these results, we can conclude that the combination of anthelmintics and immunostimulants may favor potential anthelmintic treatments for H. contortus. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-02-24 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/40310 10.5433/1679-0359.2021v42n2p707 |
url |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/40310 |
identifier_str_mv |
10.5433/1679-0359.2021v42n2p707 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/40310/29030 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Semina: Ciências Agrárias http://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 Semina: Ciências Agrárias http://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UEL |
publisher.none.fl_str_mv |
UEL |
dc.source.none.fl_str_mv |
Semina: Ciências Agrárias; Vol. 42 No. 2 (2021); 707-720 Semina: Ciências Agrárias; v. 42 n. 2 (2021); 707-720 1679-0359 1676-546X reponame:Semina. Ciências Agrárias (Online) instname:Universidade Estadual de Londrina (UEL) instacron:UEL |
instname_str |
Universidade Estadual de Londrina (UEL) |
instacron_str |
UEL |
institution |
UEL |
reponame_str |
Semina. Ciências Agrárias (Online) |
collection |
Semina. Ciências Agrárias (Online) |
repository.name.fl_str_mv |
Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL) |
repository.mail.fl_str_mv |
semina.agrarias@uel.br |
_version_ |
1799306083285598208 |