Super alimentação na infância, compromete o VO2máx. de ratos submetidos a um programa de treinamento físico moderado

• Autor(a) principal: Fabricio, Gabriel Sergio
• Data de Publicação: 2014
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
• Texto Completo: http://repositorio.uem.br:8080/jspui/handle/1/2242
• topic: Obesidade - Doenças metabólicas; Treinamento físico moderado; VO2máx; Programação metabólica; Ciências da Saúde; Educação Física

Obesity is considerate a great public health problem, having generally, as mainly causes food excess together with a low caloric expenditure. Promoting the onset of many diseases such as type 2 Diabetes. Weight excess is a determinant factor in absolute levels of maximal oxygen uptake. (VO2max.), and exercise is an important tool for treatment and prevention of obesity. Thus, the present study aimed investigate if the metabolic programming for obesity whereby litter size, could impaired the absolute levels of VO2max. of rats submitted different moderated physical training programs lifelong. Methodology: Pregnant Wistar rats were allocated separately in individual boxes. After born, offspring were adjusted for 9 pups (Norma Litter ? NN). For process small litter size (NR), in third day after born, the offspring were reduced for 3 pups per dam, for induction over nutrition. At 21-days-old offspring were standardized in 3 animals per box and divided this way: NN sedentary (NN SED); NN exercised Negrão (NN NE); NN exercised New protocol (NN NP) and NR sedentary (NR SED); NR exercised Negrão; (NR NE); NR exercised New protocol (NR NP). Only males animals were utilized. Between 21 and 90 days-old the animals were submitted to the respective training protocols in treadmill (moderate intensity). At 30, 45, 60, 75, 90 days-old, all animals including sedentary were submitted a maximal effort test for determination of VO2max. At 90 days-old, after the last effort test, the animals were fasted (12 hours), for realization of intravenous glucose tolerance test (ivGTT). After this, the animals were sacrificed with lethal doses of anesthesia and retroperitoneal fat was removed. Results: The exercise protocols were able in reduced body weight when compared with your sedentary congener. Similarly glycemia and retroperitoneal fat were reduced too. With relationship VO2máx. the animals NR exercised independently of exercise protocol don?t showed gain in VO2max. like to normal animals. Like this, the final workload also was impaired. Conclusion: The exercise protocols weren?t able to produce similar gain the controls animals in the maximal oxygen uptake in metabolic programming animals for obesity. One possible explanation could be relationship with weight excess, and is hypothesized that small litter animals could show low amount of key proteins responsible for transportation of glucose during the exercise.