Generating DNA profile from low copy number DNA: Strategies and associated risks

Detalhes bibliográficos
Autor(a) principal: Mateen, Rana Muhammad
Data de Publicação: 2020
Outros Autores: Tariq, Asma, Hussain, Mureed
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Scientiarum Biological Sciences
Texto Completo: http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/52239
Resumo: Many shreds of evidence found on the crime scenes contain a trace amount of DNA which results in insignificant profiling results for subsequent comparison. This can nullify the potential evidence material and hamper investigation process. Over the years, different strategies have been employed by various DNA testing laboratories to create interpretable DNA profiles generated from low template of DNA. This review highlights different strategies used by forensic laboratories worldwide for creating complete DNA profiles from low copy number template for comparison purposes along with its associated risks for forensic purposes
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spelling Generating DNA profile from low copy number DNA: Strategies and associated risksGenerating DNA profile from low copy number DNA: Strategies and associated risksSTR profiling; forensic genetics; likelihood ratio; random match probability.STR profiling; forensic genetics; likelihood ratio; random match probability.Many shreds of evidence found on the crime scenes contain a trace amount of DNA which results in insignificant profiling results for subsequent comparison. This can nullify the potential evidence material and hamper investigation process. Over the years, different strategies have been employed by various DNA testing laboratories to create interpretable DNA profiles generated from low template of DNA. This review highlights different strategies used by forensic laboratories worldwide for creating complete DNA profiles from low copy number template for comparison purposes along with its associated risks for forensic purposesMany shreds of evidence found on the crime scenes contain a trace amount of DNA which results in insignificant profiling results for subsequent comparison. This can nullify the potential evidence material and hamper investigation process. Over the years, different strategies have been employed by various DNA testing laboratories to create interpretable DNA profiles generated from low template of DNA. This review highlights different strategies used by forensic laboratories worldwide for creating complete DNA profiles from low copy number template for comparison purposes along with its associated risks for forensic purposesUniversidade Estadual De Maringá2020-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/5223910.4025/actascibiolsci.v42i1.52239Acta Scientiarum. Biological Sciences; Vol 42 (2020): Publicação contínua; e52239Acta Scientiarum. Biological Sciences; v. 42 (2020): Publicação contínua; e522391807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMenghttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/52239/751375150234Copyright (c) 2020 Acta Scientiarum. Biological Scienceshttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMateen, Rana MuhammadTariq, Asma Hussain, Mureed 2020-11-16T16:25:43Zoai:periodicos.uem.br/ojs:article/52239Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2020-11-16T16:25:43Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false
dc.title.none.fl_str_mv Generating DNA profile from low copy number DNA: Strategies and associated risks
Generating DNA profile from low copy number DNA: Strategies and associated risks
title Generating DNA profile from low copy number DNA: Strategies and associated risks
spellingShingle Generating DNA profile from low copy number DNA: Strategies and associated risks
Mateen, Rana Muhammad
STR profiling; forensic genetics; likelihood ratio; random match probability.
STR profiling; forensic genetics; likelihood ratio; random match probability.
title_short Generating DNA profile from low copy number DNA: Strategies and associated risks
title_full Generating DNA profile from low copy number DNA: Strategies and associated risks
title_fullStr Generating DNA profile from low copy number DNA: Strategies and associated risks
title_full_unstemmed Generating DNA profile from low copy number DNA: Strategies and associated risks
title_sort Generating DNA profile from low copy number DNA: Strategies and associated risks
author Mateen, Rana Muhammad
author_facet Mateen, Rana Muhammad
Tariq, Asma
Hussain, Mureed
author_role author
author2 Tariq, Asma
Hussain, Mureed
author2_role author
author
dc.contributor.author.fl_str_mv Mateen, Rana Muhammad
Tariq, Asma
Hussain, Mureed
dc.subject.por.fl_str_mv STR profiling; forensic genetics; likelihood ratio; random match probability.
STR profiling; forensic genetics; likelihood ratio; random match probability.
topic STR profiling; forensic genetics; likelihood ratio; random match probability.
STR profiling; forensic genetics; likelihood ratio; random match probability.
description Many shreds of evidence found on the crime scenes contain a trace amount of DNA which results in insignificant profiling results for subsequent comparison. This can nullify the potential evidence material and hamper investigation process. Over the years, different strategies have been employed by various DNA testing laboratories to create interpretable DNA profiles generated from low template of DNA. This review highlights different strategies used by forensic laboratories worldwide for creating complete DNA profiles from low copy number template for comparison purposes along with its associated risks for forensic purposes
publishDate 2020
dc.date.none.fl_str_mv 2020-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/52239
10.4025/actascibiolsci.v42i1.52239
url http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/52239
identifier_str_mv 10.4025/actascibiolsci.v42i1.52239
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/52239/751375150234
dc.rights.driver.fl_str_mv Copyright (c) 2020 Acta Scientiarum. Biological Sciences
http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Acta Scientiarum. Biological Sciences
http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual De Maringá
publisher.none.fl_str_mv Universidade Estadual De Maringá
dc.source.none.fl_str_mv Acta Scientiarum. Biological Sciences; Vol 42 (2020): Publicação contínua; e52239
Acta Scientiarum. Biological Sciences; v. 42 (2020): Publicação contínua; e52239
1807-863X
1679-9283
reponame:Acta Scientiarum Biological Sciences
instname:Universidade Estadual de Maringá (UEM)
instacron:UEM
instname_str Universidade Estadual de Maringá (UEM)
instacron_str UEM
institution UEM
reponame_str Acta Scientiarum Biological Sciences
collection Acta Scientiarum Biological Sciences
repository.name.fl_str_mv Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)
repository.mail.fl_str_mv ||actabiol@uem.br
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