Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667

Detalhes bibliográficos
Autor(a) principal: Fregonesi, Cristina Elena Prado Teles
Data de Publicação: 2008
Outros Autores: Molinari, Sônia Lucy, Miranda Neto, Marcílio Hubner de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Acta Scientiarum Biological Sciences
Texto Completo: http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1667
Resumo: The aim of this study was to analyze the morphoquantitative features of the nitrergic myenteric neurons from the body of the stomach of diabetic rats. The body of the stomach of five normoglicemic rats and of five diabetic rats were prepared as whole-mounts stained by the histochemical technique of NADPH-diaphorase. Decreased body weight and increased daily ingestion of water, fast glicemia and glycated hemoglobin were verified in diabetic animals. According to the data obtained, significant difference in the density of nitrergic neurons was not observed between the two groups, but the areas of the neuronal cell body profiles in the diabetic rats were significantly larger. Results showed that the streptozotocin that induced diabetes does not accelerate the death of the nitrergic neurons, but increases the expression of these cells
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spelling Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667Avaliação da população de neurônios mioentéricos NADPH-diaforase positivos do corpo do estômago de ratos com diabetes crônico induzido pela estreptozootocina - DOI: 10.4025/actascibiolsci.v26i1.1667diabetesplexo mioentériconeurônios nitrérgicosestômago de ratos2.01.00.00-0 Biologia GeralThe aim of this study was to analyze the morphoquantitative features of the nitrergic myenteric neurons from the body of the stomach of diabetic rats. The body of the stomach of five normoglicemic rats and of five diabetic rats were prepared as whole-mounts stained by the histochemical technique of NADPH-diaphorase. Decreased body weight and increased daily ingestion of water, fast glicemia and glycated hemoglobin were verified in diabetic animals. According to the data obtained, significant difference in the density of nitrergic neurons was not observed between the two groups, but the areas of the neuronal cell body profiles in the diabetic rats were significantly larger. Results showed that the streptozotocin that induced diabetes does not accelerate the death of the nitrergic neurons, but increases the expression of these cellsO presente estudo teve por objetivo analisar as características morfoquantitativas de neurônios mioentéricos nitrérgicos do corpo do estômago de ratos diabéticos. O corpo do estômago de 5 ratos normoglicêmicos e de 5 ratos diabéticos foi submetido a preparados de membrana corados pela técnica histoquímica da NADPH-diaforase. Verificaram-se, nos animais diabéticos, diminuição do peso corporal, aumento do consumo diário de água, da glicemia em jejum e da hemoglobina glicada. Com os dados obtidos, não foi observada diferença significativa na densidade de neurônios nitrérgicos entre os dois grupos, porém as áreas dos perfis celulares neuronais dos ratos diabéticos foram significativamente maiores. Constatou-se, portanto, que o diabetes induzido por estreptozootocina não acelera a morte dos neurônios nitrérgicos, contudo aumenta a expressão desses neurôniosUniversidade Estadual De Maringá2008-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/166710.4025/actascibiolsci.v26i1.1667Acta Scientiarum. Biological Sciences; Vol 26 No 1 (2004); 107-112Acta Scientiarum. Biological Sciences; v. 26 n. 1 (2004); 107-1121807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMporhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1667/1008Fregonesi, Cristina Elena Prado TelesMolinari, Sônia LucyMiranda Neto, Marcílio Hubner deinfo:eu-repo/semantics/openAccess2022-11-23T17:33:15Zoai:periodicos.uem.br/ojs:article/1667Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2022-11-23T17:33:15Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false
dc.title.none.fl_str_mv Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667
Avaliação da população de neurônios mioentéricos NADPH-diaforase positivos do corpo do estômago de ratos com diabetes crônico induzido pela estreptozootocina - DOI: 10.4025/actascibiolsci.v26i1.1667
title Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667
spellingShingle Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667
Fregonesi, Cristina Elena Prado Teles
diabetes
plexo mioentérico
neurônios nitrérgicos
estômago de ratos
2.01.00.00-0 Biologia Geral
title_short Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667
title_full Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667
title_fullStr Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667
title_full_unstemmed Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667
title_sort Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667
author Fregonesi, Cristina Elena Prado Teles
author_facet Fregonesi, Cristina Elena Prado Teles
Molinari, Sônia Lucy
Miranda Neto, Marcílio Hubner de
author_role author
author2 Molinari, Sônia Lucy
Miranda Neto, Marcílio Hubner de
author2_role author
author
dc.contributor.author.fl_str_mv Fregonesi, Cristina Elena Prado Teles
Molinari, Sônia Lucy
Miranda Neto, Marcílio Hubner de
dc.subject.por.fl_str_mv diabetes
plexo mioentérico
neurônios nitrérgicos
estômago de ratos
2.01.00.00-0 Biologia Geral
topic diabetes
plexo mioentérico
neurônios nitrérgicos
estômago de ratos
2.01.00.00-0 Biologia Geral
description The aim of this study was to analyze the morphoquantitative features of the nitrergic myenteric neurons from the body of the stomach of diabetic rats. The body of the stomach of five normoglicemic rats and of five diabetic rats were prepared as whole-mounts stained by the histochemical technique of NADPH-diaphorase. Decreased body weight and increased daily ingestion of water, fast glicemia and glycated hemoglobin were verified in diabetic animals. According to the data obtained, significant difference in the density of nitrergic neurons was not observed between the two groups, but the areas of the neuronal cell body profiles in the diabetic rats were significantly larger. Results showed that the streptozotocin that induced diabetes does not accelerate the death of the nitrergic neurons, but increases the expression of these cells
publishDate 2008
dc.date.none.fl_str_mv 2008-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1667
10.4025/actascibiolsci.v26i1.1667
url http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1667
identifier_str_mv 10.4025/actascibiolsci.v26i1.1667
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1667/1008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual De Maringá
publisher.none.fl_str_mv Universidade Estadual De Maringá
dc.source.none.fl_str_mv Acta Scientiarum. Biological Sciences; Vol 26 No 1 (2004); 107-112
Acta Scientiarum. Biological Sciences; v. 26 n. 1 (2004); 107-112
1807-863X
1679-9283
reponame:Acta Scientiarum Biological Sciences
instname:Universidade Estadual de Maringá (UEM)
instacron:UEM
instname_str Universidade Estadual de Maringá (UEM)
instacron_str UEM
institution UEM
reponame_str Acta Scientiarum Biological Sciences
collection Acta Scientiarum Biological Sciences
repository.name.fl_str_mv Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)
repository.mail.fl_str_mv ||actabiol@uem.br
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