Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)

Detalhes bibliográficos
Autor(a) principal: Sanches, Neviton Rogerio
Data de Publicação: 2008
Outros Autores: Galleto, Ricardo, Oliveira, Carlos Eduardo de, Bazotte, Roberto Barbosa, Cortez, Diógenes Aparício Garcia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Acta Scientiarum Biological Sciences
Texto Completo: http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729
Resumo: The roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effect
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spelling Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)Avaliação do potencial anti-hiperglicemiante da Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)Pfaffia glomerataAmaranthaceaeantihiperglicemiantebeta-ecdisona2.00.00.00-6 Ciências BiológicasThe roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effectAs raízes de Pfaffia glomerata (Spreng.) Pedersen, conhecida como ginseng brasileiro, são utilizadas na medicina popular como tônico afrodisíaco e antidiabético. O extrato metanólico bruto e suas frações obtidos das raízes foram utilizados para avaliar a atividade anti-hiperglicemiante em ratos da linhagem Wistar. Das quatro frações obtidas do extrato metanólico bruto, o extrato butanólico apresentou maior atividade anti-hiperglicemiante a partir de 50 mg/kg e o seu fracionamento resultou em perda desta atividade. A β-ecdisona identificada no extrato butanólico não está relacionada com a atividade anti-hiperglicemianteUniversidade Estadual De Maringá2008-05-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/272910.4025/actascibiolsci.v23i0.2729Acta Scientiarum. Biological Sciences; Vol 23 (2001); 613-617Acta Scientiarum. Biological Sciences; v. 23 (2001); 613-6171807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMporhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729/2040Sanches, Neviton RogerioGalleto, RicardoOliveira, Carlos Eduardo deBazotte, Roberto BarbosaCortez, Diógenes Aparício Garciainfo:eu-repo/semantics/openAccess2022-11-23T17:33:29Zoai:periodicos.uem.br/ojs:article/2729Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2022-11-23T17:33:29Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false
dc.title.none.fl_str_mv Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
Avaliação do potencial anti-hiperglicemiante da Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
title Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
spellingShingle Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
Sanches, Neviton Rogerio
Pfaffia glomerata
Amaranthaceae
antihiperglicemiante
beta-ecdisona
2.00.00.00-6 Ciências Biológicas
title_short Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
title_full Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
title_fullStr Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
title_full_unstemmed Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
title_sort Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
author Sanches, Neviton Rogerio
author_facet Sanches, Neviton Rogerio
Galleto, Ricardo
Oliveira, Carlos Eduardo de
Bazotte, Roberto Barbosa
Cortez, Diógenes Aparício Garcia
author_role author
author2 Galleto, Ricardo
Oliveira, Carlos Eduardo de
Bazotte, Roberto Barbosa
Cortez, Diógenes Aparício Garcia
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Sanches, Neviton Rogerio
Galleto, Ricardo
Oliveira, Carlos Eduardo de
Bazotte, Roberto Barbosa
Cortez, Diógenes Aparício Garcia
dc.subject.por.fl_str_mv Pfaffia glomerata
Amaranthaceae
antihiperglicemiante
beta-ecdisona
2.00.00.00-6 Ciências Biológicas
topic Pfaffia glomerata
Amaranthaceae
antihiperglicemiante
beta-ecdisona
2.00.00.00-6 Ciências Biológicas
description The roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effect
publishDate 2008
dc.date.none.fl_str_mv 2008-05-09
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729
10.4025/actascibiolsci.v23i0.2729
url http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729
identifier_str_mv 10.4025/actascibiolsci.v23i0.2729
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729/2040
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual De Maringá
publisher.none.fl_str_mv Universidade Estadual De Maringá
dc.source.none.fl_str_mv Acta Scientiarum. Biological Sciences; Vol 23 (2001); 613-617
Acta Scientiarum. Biological Sciences; v. 23 (2001); 613-617
1807-863X
1679-9283
reponame:Acta Scientiarum Biological Sciences
instname:Universidade Estadual de Maringá (UEM)
instacron:UEM
instname_str Universidade Estadual de Maringá (UEM)
instacron_str UEM
institution UEM
reponame_str Acta Scientiarum Biological Sciences
collection Acta Scientiarum Biological Sciences
repository.name.fl_str_mv Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)
repository.mail.fl_str_mv ||actabiol@uem.br
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