Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Acta Scientiarum Biological Sciences |
Texto Completo: | http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729 |
Resumo: | The roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effect |
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Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)Avaliação do potencial anti-hiperglicemiante da Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)Pfaffia glomerataAmaranthaceaeantihiperglicemiantebeta-ecdisona2.00.00.00-6 Ciências BiológicasThe roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effectAs raízes de Pfaffia glomerata (Spreng.) Pedersen, conhecida como ginseng brasileiro, são utilizadas na medicina popular como tônico afrodisíaco e antidiabético. O extrato metanólico bruto e suas frações obtidos das raízes foram utilizados para avaliar a atividade anti-hiperglicemiante em ratos da linhagem Wistar. Das quatro frações obtidas do extrato metanólico bruto, o extrato butanólico apresentou maior atividade anti-hiperglicemiante a partir de 50 mg/kg e o seu fracionamento resultou em perda desta atividade. A β-ecdisona identificada no extrato butanólico não está relacionada com a atividade anti-hiperglicemianteUniversidade Estadual De Maringá2008-05-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/272910.4025/actascibiolsci.v23i0.2729Acta Scientiarum. Biological Sciences; Vol 23 (2001); 613-617Acta Scientiarum. Biological Sciences; v. 23 (2001); 613-6171807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMporhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729/2040Sanches, Neviton RogerioGalleto, RicardoOliveira, Carlos Eduardo deBazotte, Roberto BarbosaCortez, Diógenes Aparício Garciainfo:eu-repo/semantics/openAccess2022-11-23T17:33:29Zoai:periodicos.uem.br/ojs:article/2729Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2022-11-23T17:33:29Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false |
dc.title.none.fl_str_mv |
Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) Avaliação do potencial anti-hiperglicemiante da Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) |
title |
Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) |
spellingShingle |
Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) Sanches, Neviton Rogerio Pfaffia glomerata Amaranthaceae antihiperglicemiante beta-ecdisona 2.00.00.00-6 Ciências Biológicas |
title_short |
Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) |
title_full |
Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) |
title_fullStr |
Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) |
title_full_unstemmed |
Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) |
title_sort |
Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae) |
author |
Sanches, Neviton Rogerio |
author_facet |
Sanches, Neviton Rogerio Galleto, Ricardo Oliveira, Carlos Eduardo de Bazotte, Roberto Barbosa Cortez, Diógenes Aparício Garcia |
author_role |
author |
author2 |
Galleto, Ricardo Oliveira, Carlos Eduardo de Bazotte, Roberto Barbosa Cortez, Diógenes Aparício Garcia |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Sanches, Neviton Rogerio Galleto, Ricardo Oliveira, Carlos Eduardo de Bazotte, Roberto Barbosa Cortez, Diógenes Aparício Garcia |
dc.subject.por.fl_str_mv |
Pfaffia glomerata Amaranthaceae antihiperglicemiante beta-ecdisona 2.00.00.00-6 Ciências Biológicas |
topic |
Pfaffia glomerata Amaranthaceae antihiperglicemiante beta-ecdisona 2.00.00.00-6 Ciências Biológicas |
description |
The roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effect |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-05-09 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729 10.4025/actascibiolsci.v23i0.2729 |
url |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729 |
identifier_str_mv |
10.4025/actascibiolsci.v23i0.2729 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729/2040 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual De Maringá |
publisher.none.fl_str_mv |
Universidade Estadual De Maringá |
dc.source.none.fl_str_mv |
Acta Scientiarum. Biological Sciences; Vol 23 (2001); 613-617 Acta Scientiarum. Biological Sciences; v. 23 (2001); 613-617 1807-863X 1679-9283 reponame:Acta Scientiarum Biological Sciences instname:Universidade Estadual de Maringá (UEM) instacron:UEM |
instname_str |
Universidade Estadual de Maringá (UEM) |
instacron_str |
UEM |
institution |
UEM |
reponame_str |
Acta Scientiarum Biological Sciences |
collection |
Acta Scientiarum Biological Sciences |
repository.name.fl_str_mv |
Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM) |
repository.mail.fl_str_mv |
||actabiol@uem.br |
_version_ |
1799317390965604352 |