Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665

Detalhes bibliográficos
Autor(a) principal: Silva, Maria Fernanda P. Tomasi Baldez da
Data de Publicação: 2008
Outros Autores: Ferrari, Gisele Pezente, Toledo, Fabiana de, Rocha, Carmem Lucia M. Sartori Cardoso da, Vicentini, Veronica Elisa Pimenta
Tipo de documento: Artigo
Idioma: por
Título da fonte: Acta Scientiarum Biological Sciences
Texto Completo: http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1665
Resumo: Intense industrial development and population growth have been altering the quality of water and innumerous studies have been undertaken to analyze their effects on humans. Due to rivers contamination with agrotoxics, herbicides, pesticides, excess of farming chemical additives and through sewers spilling not properly treated industrial waste, investigating cytotoxic and mutagenic activity of river water becomes all-important. Bone marrow cells of Wistar rats (Rattus norvegicus), treated in vivo, through gavage, in subchronic treatment (7 days), were used as experimental animal test system to investigate the effects of well water and water from the rivers Ficha and Minas Gerais, close to the municipality of Ubiratã, State of Paraná, southern Brazil. Cell division index and metaphase chromosomes were analyzed. The statistical analysis showed that the experiment's water failed to alter cell division cycle of Wistar rats and did not increase number of chromosome aberrations. No cytotoxic and clastogenic effects ensued from this treatment
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spelling Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665Efeito mutagênico da água natural (poço, rios Ficha e Minas Gerais, próximos à cidade de Ubiratã, Estado do Paraná, Brasil) em sistema teste animal - DOI: 10.4025/actascibiolsci.v26i1.1665mutagêneseágua naturalratos Wistar2.01.00.00-0 Biologia GeralIntense industrial development and population growth have been altering the quality of water and innumerous studies have been undertaken to analyze their effects on humans. Due to rivers contamination with agrotoxics, herbicides, pesticides, excess of farming chemical additives and through sewers spilling not properly treated industrial waste, investigating cytotoxic and mutagenic activity of river water becomes all-important. Bone marrow cells of Wistar rats (Rattus norvegicus), treated in vivo, through gavage, in subchronic treatment (7 days), were used as experimental animal test system to investigate the effects of well water and water from the rivers Ficha and Minas Gerais, close to the municipality of Ubiratã, State of Paraná, southern Brazil. Cell division index and metaphase chromosomes were analyzed. The statistical analysis showed that the experiment's water failed to alter cell division cycle of Wistar rats and did not increase number of chromosome aberrations. No cytotoxic and clastogenic effects ensued from this treatmentO intenso desenvolvimento industrial e crescimento populacional têm promovido alterações na qualidade da água, sendo esta fonte de muitos estudos para análise desses efeitos no ser humano. Devido a contaminação dos rios por agrotóxicos, herbicidas, pesticidas e demais aditivos químicos utilizados nas lavouras, e pelas indústrias que despejam através de esgotos, resíduos de sua produção, que não são devidamente tratados, torna-se importante a investigação da atividade citotóxica e mutagênica da água dos rios. Neste estudo foi utilizado como sistema teste animal as células da medula óssea de ratos Wistar (,em>Rattus norvegicus), tratados in vivo, via gavagem, de forma subcrônica (7 dias), para investigação dos efeitos das águas do poço, e dos rios Ficha e Minas Gerais, próximos à Ubiratã, Estado do Paraná, Brasil, analisando-se o ciclo de divisão celular e os cromossomos metafásicos. A análise estatística demonstrou que as águas não alteraram o ciclo de divisão celular dos ratos Wistar e também não provocaram aumento no número de aberrações cromossômicas, mostrando não terem neste tratamento, efeito citotóxico e nem clastogênicoUniversidade Estadual De Maringá2008-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/166510.4025/actascibiolsci.v26i1.1665Acta Scientiarum. Biological Sciences; Vol 26 No 1 (2004); 101-105Acta Scientiarum. Biological Sciences; v. 26 n. 1 (2004); 101-1051807-863X1679-9283reponame:Acta Scientiarum Biological Sciencesinstname:Universidade Estadual de Maringá (UEM)instacron:UEMporhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1665/1007Silva, Maria Fernanda P. Tomasi Baldez daFerrari, Gisele PezenteToledo, Fabiana deRocha, Carmem Lucia M. Sartori Cardoso daVicentini, Veronica Elisa Pimentainfo:eu-repo/semantics/openAccess2022-11-23T17:33:15Zoai:periodicos.uem.br/ojs:article/1665Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/oai||actabiol@uem.br1807-863X1679-9283opendoar:2022-11-23T17:33:15Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)false
dc.title.none.fl_str_mv Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665
Efeito mutagênico da água natural (poço, rios Ficha e Minas Gerais, próximos à cidade de Ubiratã, Estado do Paraná, Brasil) em sistema teste animal - DOI: 10.4025/actascibiolsci.v26i1.1665
title Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665
spellingShingle Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665
Silva, Maria Fernanda P. Tomasi Baldez da
mutagênese
água natural
ratos Wistar
2.01.00.00-0 Biologia Geral
title_short Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665
title_full Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665
title_fullStr Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665
title_full_unstemmed Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665
title_sort Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665
author Silva, Maria Fernanda P. Tomasi Baldez da
author_facet Silva, Maria Fernanda P. Tomasi Baldez da
Ferrari, Gisele Pezente
Toledo, Fabiana de
Rocha, Carmem Lucia M. Sartori Cardoso da
Vicentini, Veronica Elisa Pimenta
author_role author
author2 Ferrari, Gisele Pezente
Toledo, Fabiana de
Rocha, Carmem Lucia M. Sartori Cardoso da
Vicentini, Veronica Elisa Pimenta
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Maria Fernanda P. Tomasi Baldez da
Ferrari, Gisele Pezente
Toledo, Fabiana de
Rocha, Carmem Lucia M. Sartori Cardoso da
Vicentini, Veronica Elisa Pimenta
dc.subject.por.fl_str_mv mutagênese
água natural
ratos Wistar
2.01.00.00-0 Biologia Geral
topic mutagênese
água natural
ratos Wistar
2.01.00.00-0 Biologia Geral
description Intense industrial development and population growth have been altering the quality of water and innumerous studies have been undertaken to analyze their effects on humans. Due to rivers contamination with agrotoxics, herbicides, pesticides, excess of farming chemical additives and through sewers spilling not properly treated industrial waste, investigating cytotoxic and mutagenic activity of river water becomes all-important. Bone marrow cells of Wistar rats (Rattus norvegicus), treated in vivo, through gavage, in subchronic treatment (7 days), were used as experimental animal test system to investigate the effects of well water and water from the rivers Ficha and Minas Gerais, close to the municipality of Ubiratã, State of Paraná, southern Brazil. Cell division index and metaphase chromosomes were analyzed. The statistical analysis showed that the experiment's water failed to alter cell division cycle of Wistar rats and did not increase number of chromosome aberrations. No cytotoxic and clastogenic effects ensued from this treatment
publishDate 2008
dc.date.none.fl_str_mv 2008-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1665
10.4025/actascibiolsci.v26i1.1665
url http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1665
identifier_str_mv 10.4025/actascibiolsci.v26i1.1665
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1665/1007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual De Maringá
publisher.none.fl_str_mv Universidade Estadual De Maringá
dc.source.none.fl_str_mv Acta Scientiarum. Biological Sciences; Vol 26 No 1 (2004); 101-105
Acta Scientiarum. Biological Sciences; v. 26 n. 1 (2004); 101-105
1807-863X
1679-9283
reponame:Acta Scientiarum Biological Sciences
instname:Universidade Estadual de Maringá (UEM)
instacron:UEM
instname_str Universidade Estadual de Maringá (UEM)
instacron_str UEM
institution UEM
reponame_str Acta Scientiarum Biological Sciences
collection Acta Scientiarum Biological Sciences
repository.name.fl_str_mv Acta Scientiarum Biological Sciences - Universidade Estadual de Maringá (UEM)
repository.mail.fl_str_mv ||actabiol@uem.br
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