Morphoquantitative study of the duodenum myenteric plexus from rats subjected to lack of proteic and complex B vitamins - DOI: 10.4025/actascibiolsci.v26i2.1642

• Autor(a) principal: Mello, Sônia Trannin de
• Data de Publicação: 2008
• Outros Autores: Liberti, Edson Aparecido, Sant'Ana, Débora de Mello Gonçalves, Molinari, Sonia Lucy, Miranda Neto, Marcilio Hubner de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Acta Scientiarum Biological Sciences
• DOI: 10.4025/actascibiolsci.v26i2.1642
• Texto Completo: http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/1642
• topic: desnutrição protéica e vitamínica; duodeno; ratos adultos; ultraestrutura; 2.01.00.00-0 Biologia Geral

This study aims to evaluate the effects of protein and vitamin deficiency on the neurons of the duodenum myenteric plexus of rats. 24 90-day old animals were divided in two groups: control (n=12) and experimental (n=12). During 120 days, the control group received chow with 22% protein level, vitamins and minerals; the experimental group was fed with 8%-protein chow, without vitamin supplementation. After the experimental period, the animals’ blood was collected and the duodenum was removed for ultrastructural and morphoquantitative analyses (NADH-d; NADPH-d). The experimental group had reduced total protein, plasma albumin and body weight lower than the control group. The density (NADPH-d) was higher and significant for the experimental group; with the NADH-d technique the neuronal profile differed between the groups. The ultrastructural aspects were similar in both groups. The results allow the conclusion that the diet caused a moderate deficiency, not leading to quantitative alterations, but changed the neuronal profile