Comparison of metabolic parameters in children and adolescents with and without insulin resistance

• Autor(a) principal: Lemos, Leandro Coelho
• Data de Publicação: 2018
• Outros Autores: Suzuki, Claudio Shigueki, Machado-Rodrigues, Aristides, Souza, William Cordeiro de, Ferreira, Sandra Aires, Kühl, Adriana Masiero, Cavazzotto, Timothy Gustavo, Queiroga, Marcos Roberto, Mascarenhas, Luis Paulo Gomes
• Tipo de documento: Artigo
• Idioma: por; eng
• Título da fonte: Journal of Physical Education (Maringá)
• Texto Completo: https://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/37901
• topic: Obesity; Adolescents; Metabolism.; Obesidade; Adolescentes; Metabolismo.

The aim of the study wast o compare the behavior of metabolic parameters, blood pressure and obesity indicators in children and adolescents with and without insulin resistance. Sixty-one overweight children (6 to 18 years) who underwent anthropometric measurements of body mass (MC), height and waist circumference (WC), blood pressure (BP), bioimpedance (relative fat (%G) and absolute (GC)) and blood collection for determination of glucose, insulin and lipid profile (TG, CT, HDL-C, LDL-C). The IMC z-score was used to classify the nutritional status and the HOMA-RI index (> 2.5) for insulin resistance. Participants were divided into two groups, resistant (RI, n= 27) and non-insulin resistant (NRI, n= 33). Regardless of age, children and adolescents with excess weight and IR presented higher MC, CC, BMI, %G and GC (kg), TG and plasma insulin than NRI counterparts, which in turn had higher LDL-C. The groups did not differ for the nutritional status (IMC z-score); however, in the comparison between the undesired proportions of the metabolic components, only three presented alterations with significant differences between the groups (TC, LDL-C and TG). It is concluded that IR is an influence for the development of dyslipidemias in this age group, especially TG.