Estudo fitoquímico das partes aéreas da Melochia tomentosa L.
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UEPB |
Texto Completo: | http://tede.bc.uepb.edu.br/jspui/handle/tede/4813 |
Resumo: | Ancient reports reveal the use of natural products for the most diverse purposes, such as therapeutic, agricultural, defense mechanisms against pests and in the search for relief or cure of illnesses. Currently, the culture of using medicinal plants to treat diseases remains alive. The Malvaceae family represents a group of plants widely spread throughout Brazil, especially in the Southeast and Northeast regions. The species Melochia tomentosa L., popularly known as ‘Malva-roxa’ or ‘Candieiro’, is a herb native from the caatinga of Brazilian Northeastern usually used to treat flu, colds, bronchitis and lung inflammation. The literature reports the isolation and identification of twenty-four chemical constituents in few studies, which makes this species the target of this research. Considering that, the present work aims to carry out a phytochemical study on the aerial parts of the species M. tomentosa and investigate the antioxidant potential in order to contribute to the taxonomic and biological knowledge of the Malvaceae family. The aerial parts of the species were collected in August 2022, in the rural area of Jataúba City, Pernambuco. Using the collected botanical material, an exsicata was prepared and deposited in the Jaime Coelho de Moraes Herbarium, at the Agricultural Sciences Center, at the Federal University of Paraíba (CCA/UFPB). After being dried and crushed, the plant material was submitted to Soxhlet and maceration extraction, producing n-hexane, chloroform, methanolic and ethanolic extracts, which were submitted to phytochemical study, quantification of Total Flavonoids, and compound identification by LC-MS, as well as biological assays to investigate its antioxidant activity as described in the literature. The results obtained indicated that alkaloids, steroids, tannins, flavonoids and coumarins are present in the aerial parts of M. tomentosa. Through phytochemical screening with hexane, chloroform and methanolic extracts from the aerial parts of M. tomentosa, it was possible to characterize the presence of alkaloids, steroids, tannins, flavonoids and coumarins. The total flavonoid content for these extracts was quantified at 2.04 mg, 2.38 mg and 2.33 mg EQ/g, respectively, indicating promising chemical and biological potential. The chromatographic fractionation of the methanolic extract allowed the obtaining of fractions that, after analysis by LC-MS, led to the identification of 20 compounds (identified for the first time in the species), of which 12 are flavonoids, with emphasis on the peak majority characterized as the glycosylated flavonoid tiliroside, widely isolated from Malvaceae species and known for a wide range of biological activities. The evaluation of the antioxidant potential of EEB by the DPPH assay showed an EC50 value = 121.81 μg/mL, demonstrating a good profile in the elimination of these free radicals, corroborating data described in the literature. The results obtained contributed to the chemical and biological profile of the Malvaceae s.l. family and encourage the continuation of studies, with the aim of isolating the identified compounds and characterizing them structurally, as well as exploring the antioxidant potential of these substances. |
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Teles, Yanna Carolina FerreiraSantos, Maria Betania Hermenegildo dosFernandes, Diégina AraújoMonteiro, Gabryella Freire2023-11-29T11:03:36Z2999-12-312023-10-31Monteiro, Gabryella Freire. Estudo fitoquímico das partes aéreas da Melochia tomentosa L. 2023. 79 f. Dissertação (Programa de Pós-Graduação em Química - PPGQ) - Universidade Estadual da Paraíba, Campina Grande - PB, 2023.http://tede.bc.uepb.edu.br/jspui/handle/tede/4813Ancient reports reveal the use of natural products for the most diverse purposes, such as therapeutic, agricultural, defense mechanisms against pests and in the search for relief or cure of illnesses. Currently, the culture of using medicinal plants to treat diseases remains alive. The Malvaceae family represents a group of plants widely spread throughout Brazil, especially in the Southeast and Northeast regions. The species Melochia tomentosa L., popularly known as ‘Malva-roxa’ or ‘Candieiro’, is a herb native from the caatinga of Brazilian Northeastern usually used to treat flu, colds, bronchitis and lung inflammation. The literature reports the isolation and identification of twenty-four chemical constituents in few studies, which makes this species the target of this research. Considering that, the present work aims to carry out a phytochemical study on the aerial parts of the species M. tomentosa and investigate the antioxidant potential in order to contribute to the taxonomic and biological knowledge of the Malvaceae family. The aerial parts of the species were collected in August 2022, in the rural area of Jataúba City, Pernambuco. Using the collected botanical material, an exsicata was prepared and deposited in the Jaime Coelho de Moraes Herbarium, at the Agricultural Sciences Center, at the Federal University of Paraíba (CCA/UFPB). After being dried and crushed, the plant material was submitted to Soxhlet and maceration extraction, producing n-hexane, chloroform, methanolic and ethanolic extracts, which were submitted to phytochemical study, quantification of Total Flavonoids, and compound identification by LC-MS, as well as biological assays to investigate its antioxidant activity as described in the literature. The results obtained indicated that alkaloids, steroids, tannins, flavonoids and coumarins are present in the aerial parts of M. tomentosa. Through phytochemical screening with hexane, chloroform and methanolic extracts from the aerial parts of M. tomentosa, it was possible to characterize the presence of alkaloids, steroids, tannins, flavonoids and coumarins. The total flavonoid content for these extracts was quantified at 2.04 mg, 2.38 mg and 2.33 mg EQ/g, respectively, indicating promising chemical and biological potential. The chromatographic fractionation of the methanolic extract allowed the obtaining of fractions that, after analysis by LC-MS, led to the identification of 20 compounds (identified for the first time in the species), of which 12 are flavonoids, with emphasis on the peak majority characterized as the glycosylated flavonoid tiliroside, widely isolated from Malvaceae species and known for a wide range of biological activities. The evaluation of the antioxidant potential of EEB by the DPPH assay showed an EC50 value = 121.81 μg/mL, demonstrating a good profile in the elimination of these free radicals, corroborating data described in the literature. The results obtained contributed to the chemical and biological profile of the Malvaceae s.l. family and encourage the continuation of studies, with the aim of isolating the identified compounds and characterizing them structurally, as well as exploring the antioxidant potential of these substances.Relatos da antiguidade revelam a utilização de produtos naturais para os mais diversos fins, como terapêuticos, agrícolas, mecanismos de defesa contra pragas e na busca do alívio ou cura das enfermidades. Atualmente, a cultura da utilização de plantas medicinais para o tratamento de doenças permanece viva. A família Malvaceae representa um conjunto de vegetais amplamente difundida por todo território brasileiro, sobretudo nas regiões Sudeste e Nordeste. A espécie Melochia tomentosa L., popularmente conhecida como “Malva-roxa” ou “Candieiro”, é uma erva nativa da caatinga do Nordeste brasileiro usualmente utilizada para o tratamento de gripe, resfriado, bronquite e inflamação no pulmão. A literatura relata o isolamento e identificação de vinte e quatro constituintes químicos em escassos estudos, o que torna essa espécie alvo da referida pesquisa. Ante o exposto, o presente trabalho tem por objetivo realizar um estudo fitoquímico com as partes aéreas da espécie M. tomentosa e investigar o potencial antioxidante de forma a contribuir para o conhecimento taxonômico e biológico da família Malvaceae. As partes aéreas da espécie foram coletadas em agosto de 2022, na zona rural de Jataúba, município de Pernambuco. Através do material botânico coletado, preparou-se uma exsicata que foi depositada no Herbário Jaime Coelho de Moraes, no Centro de Ciências Agrárias, da Universidade Federal da Paraíba (CCA/UFPB). Após ser seco e triturado, o material vegetal foi submetido a extração por Soxhlet e maceração, produzindo os extratos n-hexânico, clorofórmico, metanólico e etanólico, que foram submetidos a estudo fitoquímico, quantificação de Flavonoides Totais, e identificação de composto por LC-MS, bem como a ensaios biológicos para investigar sua atividade antioxidante conforme o descrito na literatura. Os resultados obtidos indicaram que nas partes aéreas da M. tomentosa estão presentes alcaloides, esteroides, taninos, flavonoides e cumarinas. Através da triagem fitoquímica com os extratos hexânico, clorofórmico e metanólico das partes aéreas de M. tomentosa foi possível caracterizar a presença de alcaloides, esteroides, taninos, flavonoides e cumarinas. O teor de flavonoides totais para estes extratos foi quantificado em 2,04 mg, 2,38 mg e 2,33 mg EQ/g, respectivamente, indicando um promissor potencial químico e biológico. O fracionamento cromatográfico do extrato metanólico, permitiu a obtenção de frações que após análise por LC-MS, levaram a identificação de 20 compostos (identificados pela primeira vez na espécie), dos quais 12 se tratam de flavonoides, com destaque para o pico majoritário caracterizado como o flavonoide glicosilado tilirosideo, amplamente isolado de espécies de Malvaceae e conhecido por um grande leque de atividade biológicas. A avaliação do potencial antioxidante do EEB pelo ensaio DPPH, apresentou valor de EC50 = 121,81 μg/mL, demonstrando bom perfil na eliminação destes radicias livres, corroborando com dados descritos na literatura. Os resultados obtidos contribuíram para o perfil químico e biológico da família Malvaceae s.l. e impulsionam a continuação dos estudos, no intuito de isolar os compostos identificados e caracteriza-los estruturalmente, bem como explorar o potencial antioxidante destas substâncias.Submitted by Gabryella Monteiro (gabryella.freire.monteiro@aluno.uepb.edu.br) on 2023-11-28T01:11:13Z No. of bitstreams: 2 DS - Gabryella Freire Monteiro.pdf: 1564583 bytes, checksum: 78ec269cbd301a44cdf73c6d06613ac2 (MD5) Termo de depósito BDTD.pdf: 111459 bytes, checksum: 806c045ecf30de3895064bf611975410 (MD5)Approved for entry into archive by Jean Medeiros (jeanletras@uepb.edu.br) on 2023-11-28T11:43:00Z (GMT) No. of bitstreams: 2 DS - Gabryella Freire Monteiro.pdf: 1564583 bytes, checksum: 78ec269cbd301a44cdf73c6d06613ac2 (MD5) Termo de depósito BDTD.pdf: 111459 bytes, checksum: 806c045ecf30de3895064bf611975410 (MD5)Made available in DSpace on 2023-11-29T11:03:36Z (GMT). No. of bitstreams: 2 DS - Gabryella Freire Monteiro.pdf: 1564583 bytes, checksum: 78ec269cbd301a44cdf73c6d06613ac2 (MD5) Termo de depósito BDTD.pdf: 111459 bytes, checksum: 806c045ecf30de3895064bf611975410 (MD5) Previous issue date: 2023-10-31application/pdfporUniversidade Estadual da ParaíbaPrograma de Pós-Graduação em Química - PPGQUEPBBrasilPró-Reitoria de Pós-Graduação e Pesquisa - PRPGPMalvaceaeAnálise fitoquímicaFlavonoidesAtividade antioxidanteMalvaceaePhytochemical analysisFlavonoidsAntioxidant activityQUIMICA ORGANICA::QUIMICA DOS PRODUTOS NATURAISEstudo fitoquímico das partes aéreas da Melochia tomentosa L.Phytochemical study of aerial parts of Melochia tomentosa L.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-79317878423444719666006006005248714503811102784801670629162214816info:eu-repo/semantics/embargoedAccessreponame:Biblioteca Digital de Teses e Dissertações da UEPBinstname:Universidade Estadual da Paraíba (UEPB)instacron:UEPBORIGINALDS - Gabryella Freire Monteiro.pdfDS - Gabryella Freire Monteiro.pdfapplication/pdf1564583http://tede.bc.uepb.edu.br/jspui/bitstream/tede/4813/2/DS+-+Gabryella+Freire+Monteiro.pdf78ec269cbd301a44cdf73c6d06613ac2MD52Termo de depósito BDTD.pdfTermo de depósito BDTD.pdfapplication/pdf111459http://tede.bc.uepb.edu.br/jspui/bitstream/tede/4813/3/Termo+de+dep%C3%B3sito+BDTD.pdf806c045ecf30de3895064bf611975410MD53LICENSElicense.txtlicense.txttext/plain; charset=utf-81960http://tede.bc.uepb.edu.br/jspui/bitstream/tede/4813/1/license.txt6052ae61e77222b2086e666b7ae213ceMD51tede/48132023-11-29 08:03:37.392oai:tede.bc.uepb.edu.br: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede.bc.uepb.edu.br/jspui/PUBhttp://tede.bc.uepb.edu.br/oai/requestbc@uepb.edu.br||opendoar:2023-11-29T11:03:37Biblioteca Digital de Teses e Dissertações da UEPB - Universidade Estadual da Paraíba (UEPB)false |
dc.title.por.fl_str_mv |
Estudo fitoquímico das partes aéreas da Melochia tomentosa L. |
dc.title.alternative.eng.fl_str_mv |
Phytochemical study of aerial parts of Melochia tomentosa L. |
title |
Estudo fitoquímico das partes aéreas da Melochia tomentosa L. |
spellingShingle |
Estudo fitoquímico das partes aéreas da Melochia tomentosa L. Monteiro, Gabryella Freire Malvaceae Análise fitoquímica Flavonoides Atividade antioxidante Malvaceae Phytochemical analysis Flavonoids Antioxidant activity QUIMICA ORGANICA::QUIMICA DOS PRODUTOS NATURAIS |
title_short |
Estudo fitoquímico das partes aéreas da Melochia tomentosa L. |
title_full |
Estudo fitoquímico das partes aéreas da Melochia tomentosa L. |
title_fullStr |
Estudo fitoquímico das partes aéreas da Melochia tomentosa L. |
title_full_unstemmed |
Estudo fitoquímico das partes aéreas da Melochia tomentosa L. |
title_sort |
Estudo fitoquímico das partes aéreas da Melochia tomentosa L. |
author |
Monteiro, Gabryella Freire |
author_facet |
Monteiro, Gabryella Freire |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Teles, Yanna Carolina Ferreira |
dc.contributor.referee1.fl_str_mv |
Santos, Maria Betania Hermenegildo dos |
dc.contributor.referee2.fl_str_mv |
Fernandes, Diégina Araújo |
dc.contributor.author.fl_str_mv |
Monteiro, Gabryella Freire |
contributor_str_mv |
Teles, Yanna Carolina Ferreira Santos, Maria Betania Hermenegildo dos Fernandes, Diégina Araújo |
dc.subject.por.fl_str_mv |
Malvaceae Análise fitoquímica Flavonoides Atividade antioxidante |
topic |
Malvaceae Análise fitoquímica Flavonoides Atividade antioxidante Malvaceae Phytochemical analysis Flavonoids Antioxidant activity QUIMICA ORGANICA::QUIMICA DOS PRODUTOS NATURAIS |
dc.subject.eng.fl_str_mv |
Malvaceae Phytochemical analysis Flavonoids Antioxidant activity |
dc.subject.cnpq.fl_str_mv |
QUIMICA ORGANICA::QUIMICA DOS PRODUTOS NATURAIS |
description |
Ancient reports reveal the use of natural products for the most diverse purposes, such as therapeutic, agricultural, defense mechanisms against pests and in the search for relief or cure of illnesses. Currently, the culture of using medicinal plants to treat diseases remains alive. The Malvaceae family represents a group of plants widely spread throughout Brazil, especially in the Southeast and Northeast regions. The species Melochia tomentosa L., popularly known as ‘Malva-roxa’ or ‘Candieiro’, is a herb native from the caatinga of Brazilian Northeastern usually used to treat flu, colds, bronchitis and lung inflammation. The literature reports the isolation and identification of twenty-four chemical constituents in few studies, which makes this species the target of this research. Considering that, the present work aims to carry out a phytochemical study on the aerial parts of the species M. tomentosa and investigate the antioxidant potential in order to contribute to the taxonomic and biological knowledge of the Malvaceae family. The aerial parts of the species were collected in August 2022, in the rural area of Jataúba City, Pernambuco. Using the collected botanical material, an exsicata was prepared and deposited in the Jaime Coelho de Moraes Herbarium, at the Agricultural Sciences Center, at the Federal University of Paraíba (CCA/UFPB). After being dried and crushed, the plant material was submitted to Soxhlet and maceration extraction, producing n-hexane, chloroform, methanolic and ethanolic extracts, which were submitted to phytochemical study, quantification of Total Flavonoids, and compound identification by LC-MS, as well as biological assays to investigate its antioxidant activity as described in the literature. The results obtained indicated that alkaloids, steroids, tannins, flavonoids and coumarins are present in the aerial parts of M. tomentosa. Through phytochemical screening with hexane, chloroform and methanolic extracts from the aerial parts of M. tomentosa, it was possible to characterize the presence of alkaloids, steroids, tannins, flavonoids and coumarins. The total flavonoid content for these extracts was quantified at 2.04 mg, 2.38 mg and 2.33 mg EQ/g, respectively, indicating promising chemical and biological potential. The chromatographic fractionation of the methanolic extract allowed the obtaining of fractions that, after analysis by LC-MS, led to the identification of 20 compounds (identified for the first time in the species), of which 12 are flavonoids, with emphasis on the peak majority characterized as the glycosylated flavonoid tiliroside, widely isolated from Malvaceae species and known for a wide range of biological activities. The evaluation of the antioxidant potential of EEB by the DPPH assay showed an EC50 value = 121.81 μg/mL, demonstrating a good profile in the elimination of these free radicals, corroborating data described in the literature. The results obtained contributed to the chemical and biological profile of the Malvaceae s.l. family and encourage the continuation of studies, with the aim of isolating the identified compounds and characterizing them structurally, as well as exploring the antioxidant potential of these substances. |
publishDate |
2023 |
dc.date.accessioned.fl_str_mv |
2023-11-29T11:03:36Z |
dc.date.issued.fl_str_mv |
2023-10-31 |
dc.date.available.fl_str_mv |
2999-12-31 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Monteiro, Gabryella Freire. Estudo fitoquímico das partes aéreas da Melochia tomentosa L. 2023. 79 f. Dissertação (Programa de Pós-Graduação em Química - PPGQ) - Universidade Estadual da Paraíba, Campina Grande - PB, 2023. |
dc.identifier.uri.fl_str_mv |
http://tede.bc.uepb.edu.br/jspui/handle/tede/4813 |
identifier_str_mv |
Monteiro, Gabryella Freire. Estudo fitoquímico das partes aéreas da Melochia tomentosa L. 2023. 79 f. Dissertação (Programa de Pós-Graduação em Química - PPGQ) - Universidade Estadual da Paraíba, Campina Grande - PB, 2023. |
url |
http://tede.bc.uepb.edu.br/jspui/handle/tede/4813 |
dc.language.iso.fl_str_mv |
por |
language |
por |
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dc.relation.confidence.fl_str_mv |
600 600 600 |
dc.relation.department.fl_str_mv |
524871450381110278 |
dc.relation.cnpq.fl_str_mv |
4801670629162214816 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/embargoedAccess |
eu_rights_str_mv |
embargoedAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual da Paraíba |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Química - PPGQ |
dc.publisher.initials.fl_str_mv |
UEPB |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Pró-Reitoria de Pós-Graduação e Pesquisa - PRPGP |
publisher.none.fl_str_mv |
Universidade Estadual da Paraíba |
dc.source.none.fl_str_mv |
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