Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica

Detalhes bibliográficos
Autor(a) principal: Leidersnaider, Caio Leal
Data de Publicação: 2021
Outros Autores: caiofmp@gmail.com
Tipo de documento: Tese
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UERJ
Texto Completo: http://www.bdtd.uerj.br/handle/1/19522
Resumo: Chikungunya fever (CF) is an arboviral disease transmitted by Aedes mosquitoes infected with the Chikungunya virus (VCHIK). It is an epidemic in several countries around the world. The disease causes chronic and disabling arthritis for up to five years after infection and affects many of the economically active population. Study one describes, through clinical, laboratory, ultrasound (US), and magnetic resonance (MRI) data, how a 49- year-old man developed psoriatic arthritis (PA) after CF infection. The clinical picture of classic synovitis and tenosynovitis secondary to CF, the persistence of inflammatory disease with signs of enthesitis and dactylitis on US and MRI, positive family history, and the appearance of skin lesions on the scalp strongly suggested post-CF PA, according to the criteria of the American College of Rheumatology. Study two aimed to analyze the musculoskeletal changes in the wrists and hands through physical examination (PE), US, and MRI. Thirty patients with a proven laboratory diagnosis of CF were evaluated in the chronic phase of the disease. There was a predominance of females, and the average age was 54.7 years. The analyzed sites were the interphalangeal (IF), metacarpophalangeal (MCF), and wrist/midcarpal joints. The interval between PE and imaging exams was seven days, and the interval between US and MRI was at most two days. The kappa coefficient was calculated to estimate the agreement between the PE, US, and MR findings. A significant agreement was observed between PE and US in diagnosing synovitis. The only statistically significant (moderate agreement) between US and MRI was the finding of flexor tenosynovitis. US has potential for diagnostic confirmation of suspected synovitis based on positivity of the PE. The limited agreement between US and MRI for other findings, in turn, may suggest a complementary role for these methods.
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spelling Mogami, Robertohttp://lattes.cnpq.br/4300866819252154Sztajnbok, Flávio Robertohttp://lattes.cnpq.br/4277113603642992Lopes, Agnaldo Joséhttp://lattes.cnpq.br/1548788734980219Koifman, Ana Célia Baptistahttp://lattes.cnpq.br/5787376872479808Pinheiro, Geraldo da Rocha Castelarhttp://lattes.cnpq.br/7536115815141738Martins e Souza, Patríciahttp://lattes.cnpq.br/6629970038061223Abreu, Mirhelen Mendes dehttp://lattes.cnpq.br/7242246597159087http://lattes.cnpq.br/7091946696457852Leidersnaider, Caio Lealcaiofmp@gmail.com2023-05-08T13:16:12Z2021-12-10LEIDERSNAIDER, Caio Leal. Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica. 2021. 99 f. Tese (Doutorado em Ciências Médicas) – Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2021.http://www.bdtd.uerj.br/handle/1/19522Chikungunya fever (CF) is an arboviral disease transmitted by Aedes mosquitoes infected with the Chikungunya virus (VCHIK). It is an epidemic in several countries around the world. The disease causes chronic and disabling arthritis for up to five years after infection and affects many of the economically active population. Study one describes, through clinical, laboratory, ultrasound (US), and magnetic resonance (MRI) data, how a 49- year-old man developed psoriatic arthritis (PA) after CF infection. The clinical picture of classic synovitis and tenosynovitis secondary to CF, the persistence of inflammatory disease with signs of enthesitis and dactylitis on US and MRI, positive family history, and the appearance of skin lesions on the scalp strongly suggested post-CF PA, according to the criteria of the American College of Rheumatology. Study two aimed to analyze the musculoskeletal changes in the wrists and hands through physical examination (PE), US, and MRI. Thirty patients with a proven laboratory diagnosis of CF were evaluated in the chronic phase of the disease. There was a predominance of females, and the average age was 54.7 years. The analyzed sites were the interphalangeal (IF), metacarpophalangeal (MCF), and wrist/midcarpal joints. The interval between PE and imaging exams was seven days, and the interval between US and MRI was at most two days. The kappa coefficient was calculated to estimate the agreement between the PE, US, and MR findings. A significant agreement was observed between PE and US in diagnosing synovitis. The only statistically significant (moderate agreement) between US and MRI was the finding of flexor tenosynovitis. US has potential for diagnostic confirmation of suspected synovitis based on positivity of the PE. The limited agreement between US and MRI for other findings, in turn, may suggest a complementary role for these methods.A febre Chikungunya (FC) é uma doença arboviral transmitida por mosquitos Aedes infectados pelo vírus Chikungunya (VCHIK). Ela é epidêmica em vários países ao redor do mundo. A doença causa artrite crônica e incapacitante por até cinco anos após a infecção, e atinge grande parte da população economicamente ativa. O estudo um descreve, por meio de dados clínicos, laboratoriais, ultrassonográficos (US) e de ressonância magnética (RM) como um homem de 49 anos desenvolveu artrite psoriásica (AP) após infecção pela FC. O quadro de sinovite e tenossinovite clássicas secundárias à FC, a persistência de doença inflamatória com sinais de entesite e dactilite na US e RM, a história familiar positiva e o aparecimento de lesões cutâneas no couro cabeludo sugere fortemente AP pós-FC, segundo os critérios do Colégio Americano de Reumatologia. O estudo dois teve como objetivo analisar as alterações musculoesqueléticas de punhos e mãos por meio do exame físico (EF), US e RM. Trinta pacientes com diagnóstico laboratorial comprovado de FC foram avaliados na fase crônica da doença. Houve predominância do sexo feminino e a média da idade foi de 54,7 anos. Os locais analisados foram as regiões interfalângica (IF), metacarpofalângica (MCF) e articulações do punho/mediocarpal (PMC). O intervalo entre o EF e os exames de imagens foi de sete dias, e o intervalo entre a US e RM foi de no máximo dois dias. O coeficiente kappa foi calculado para estimar a concordância entre os achados de EF, US e RM. Foi observada concordância significativa entre EF e US no diagnóstico de sinovites. A única concordância estatisticamente significativa (grau moderado) entre US e RM foi o achado de tenossinovite flexora. A US tem potencial para confirmação diagnóstica na suspeita de sinovite, com base na uma positividade do EF. A limitada concordância entre US e RM para outros achados, por sua vez, pode sugerir um papel complementar destes métodos.Submitted by Heloísa CB/A (helobdtd@gmail.com) on 2023-05-08T13:16:12Z No. of bitstreams: 1 Tese - Caio Leal Leidersnaider - Completa - 2021.pdf: 3641978 bytes, checksum: 9d3dd0d68c197c51ecd5f1b577dc43d5 (MD5)Made available in DSpace on 2023-05-08T13:16:12Z (GMT). No. of bitstreams: 1 Tese - Caio Leal Leidersnaider - Completa - 2021.pdf: 3641978 bytes, checksum: 9d3dd0d68c197c51ecd5f1b577dc43d5 (MD5) Previous issue date: 2021-12-10application/pdfporUniversidade do Estado do Rio de JaneiroPrograma de Pós-Graduação em Ciências MédicasUERJBrasilCentro Biomédico::Faculdade de Ciências MédicasChikungunya feverPhysical examationUltrasoundMagnetic resonance imagingMusculoskeletalFebre ChikungunyaExame físicoUltrassonografiaRessonância magnéticaMusculoesqueléticoCIENCIAS DA SAUDE::MEDICINA::RADIOLOGIA MEDICAAnálise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônicaComparative analysis between physical examination, ultrasound, and magnetic resonance imaging of the wrists and hands in the study of clinical musculoskeletal manifestations of chronic Chikungunya feverinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UERJinstname:Universidade do Estado do Rio de Janeiro (UERJ)instacron:UERJORIGINALTese - Caio Leal Leidersnaider - 2021 - Completa.pdfTese - Caio Leal Leidersnaider - 2021 - Completa.pdfapplication/pdf3641978http://www.bdtd.uerj.br/bitstream/1/19522/2/Tese+-+Caio+Leal+Leidersnaider+-+2021+-+Completa.pdf9d3dd0d68c197c51ecd5f1b577dc43d5MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82123http://www.bdtd.uerj.br/bitstream/1/19522/1/license.txte5502652da718045d7fcd832b79fca29MD511/195222024-02-26 15:59:52.397oai:www.bdtd.uerj.br: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Biblioteca Digital de Teses e Dissertaçõeshttp://www.bdtd.uerj.br/PUBhttps://www.bdtd.uerj.br:8443/oai/requestbdtd.suporte@uerj.bropendoar:29032024-02-26T18:59:52Biblioteca Digital de Teses e Dissertações da UERJ - Universidade do Estado do Rio de Janeiro (UERJ)false
dc.title.por.fl_str_mv Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica
dc.title.alternative.eng.fl_str_mv Comparative analysis between physical examination, ultrasound, and magnetic resonance imaging of the wrists and hands in the study of clinical musculoskeletal manifestations of chronic Chikungunya fever
title Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica
spellingShingle Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica
Leidersnaider, Caio Leal
Chikungunya fever
Physical examation
Ultrasound
Magnetic resonance imaging
Musculoskeletal
Febre Chikungunya
Exame físico
Ultrassonografia
Ressonância magnética
Musculoesquelético
CIENCIAS DA SAUDE::MEDICINA::RADIOLOGIA MEDICA
title_short Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica
title_full Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica
title_fullStr Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica
title_full_unstemmed Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica
title_sort Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica
author Leidersnaider, Caio Leal
author_facet Leidersnaider, Caio Leal
caiofmp@gmail.com
author_role author
author2 caiofmp@gmail.com
author2_role author
dc.contributor.advisor1.fl_str_mv Mogami, Roberto
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/4300866819252154
dc.contributor.advisor-co1.fl_str_mv Sztajnbok, Flávio Roberto
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/4277113603642992
dc.contributor.referee1.fl_str_mv Lopes, Agnaldo José
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/1548788734980219
dc.contributor.referee2.fl_str_mv Koifman, Ana Célia Baptista
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/5787376872479808
dc.contributor.referee3.fl_str_mv Pinheiro, Geraldo da Rocha Castelar
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/7536115815141738
dc.contributor.referee4.fl_str_mv Martins e Souza, Patrícia
dc.contributor.referee4Lattes.fl_str_mv http://lattes.cnpq.br/6629970038061223
dc.contributor.referee5.fl_str_mv Abreu, Mirhelen Mendes de
dc.contributor.referee5Lattes.fl_str_mv http://lattes.cnpq.br/7242246597159087
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/7091946696457852
dc.contributor.author.fl_str_mv Leidersnaider, Caio Leal
caiofmp@gmail.com
contributor_str_mv Mogami, Roberto
Sztajnbok, Flávio Roberto
Lopes, Agnaldo José
Koifman, Ana Célia Baptista
Pinheiro, Geraldo da Rocha Castelar
Martins e Souza, Patrícia
Abreu, Mirhelen Mendes de
dc.subject.eng.fl_str_mv Chikungunya fever
Physical examation
Ultrasound
Magnetic resonance imaging
Musculoskeletal
topic Chikungunya fever
Physical examation
Ultrasound
Magnetic resonance imaging
Musculoskeletal
Febre Chikungunya
Exame físico
Ultrassonografia
Ressonância magnética
Musculoesquelético
CIENCIAS DA SAUDE::MEDICINA::RADIOLOGIA MEDICA
dc.subject.por.fl_str_mv Febre Chikungunya
Exame físico
Ultrassonografia
Ressonância magnética
Musculoesquelético
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::MEDICINA::RADIOLOGIA MEDICA
description Chikungunya fever (CF) is an arboviral disease transmitted by Aedes mosquitoes infected with the Chikungunya virus (VCHIK). It is an epidemic in several countries around the world. The disease causes chronic and disabling arthritis for up to five years after infection and affects many of the economically active population. Study one describes, through clinical, laboratory, ultrasound (US), and magnetic resonance (MRI) data, how a 49- year-old man developed psoriatic arthritis (PA) after CF infection. The clinical picture of classic synovitis and tenosynovitis secondary to CF, the persistence of inflammatory disease with signs of enthesitis and dactylitis on US and MRI, positive family history, and the appearance of skin lesions on the scalp strongly suggested post-CF PA, according to the criteria of the American College of Rheumatology. Study two aimed to analyze the musculoskeletal changes in the wrists and hands through physical examination (PE), US, and MRI. Thirty patients with a proven laboratory diagnosis of CF were evaluated in the chronic phase of the disease. There was a predominance of females, and the average age was 54.7 years. The analyzed sites were the interphalangeal (IF), metacarpophalangeal (MCF), and wrist/midcarpal joints. The interval between PE and imaging exams was seven days, and the interval between US and MRI was at most two days. The kappa coefficient was calculated to estimate the agreement between the PE, US, and MR findings. A significant agreement was observed between PE and US in diagnosing synovitis. The only statistically significant (moderate agreement) between US and MRI was the finding of flexor tenosynovitis. US has potential for diagnostic confirmation of suspected synovitis based on positivity of the PE. The limited agreement between US and MRI for other findings, in turn, may suggest a complementary role for these methods.
publishDate 2021
dc.date.issued.fl_str_mv 2021-12-10
dc.date.accessioned.fl_str_mv 2023-05-08T13:16:12Z
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dc.identifier.citation.fl_str_mv LEIDERSNAIDER, Caio Leal. Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica. 2021. 99 f. Tese (Doutorado em Ciências Médicas) – Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2021.
dc.identifier.uri.fl_str_mv http://www.bdtd.uerj.br/handle/1/19522
identifier_str_mv LEIDERSNAIDER, Caio Leal. Análise comparativa entre exame físico, ultrassonografia e ressonância magnética nos punhos e mãos no estudo das manifestações clínicas musculoesqueléticas da febre Chikungunya crônica. 2021. 99 f. Tese (Doutorado em Ciências Médicas) – Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2021.
url http://www.bdtd.uerj.br/handle/1/19522
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dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Ciências Médicas
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dc.publisher.department.fl_str_mv Centro Biomédico::Faculdade de Ciências Médicas
publisher.none.fl_str_mv Universidade do Estado do Rio de Janeiro
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