Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | http://ri.ufs.br/jspui/handle/riufs/13062 |
Resumo: | Chikungunya fever (CF) is an arbovirus caused by the chikungunya virus (CHIKV). Having as a main characteristic, joint pain and possible chronicity in more than half of infected patients. The purpose of the present study is to evaluate the persistent musculoskeletal manifestations of CF. These are a series of cases. It was evaluated a sample of 72 patients with persistent musculoskeletal disease (≥ 1 month) after the confirmation of CF by laboratory tests. These patients were monitored for 12 months and were treated at the ambulatory clinic of the University Hospital of the Federal University of Sergipe (HU / UFS). Patients were evaluated at admission, at 1 month, 2 months, and then every 3 months until 12 months. In all consultations, it was examined painful and / or swollen joints, periarticular symptoms, other important physical examination findings and VAS (visual analogue pain scale). Main results: 84.7% were female patients; the average age was 53.8 years; the average time of musculoskeletal complaints was 6 months. Comorbidities were present in 61.1% of patients and previous musculoskeletal disease was present in 69.4%. The most frequent presentation at admission was polyarticular in 76.4%. The most affected joints were: hands, knees, ankles and feet. VAS on admission was intense in most patients: 66.7%. Tenosynovitis was present in 44.5% of the patients, with ankles being more frequent. Corticosteroids were used in 65.3% of patients and chloroquine in 31.98%. It was concluded that persistent musculoskeletal manifestations after CF are frequent. After 12 months of monitoring, more than half of the patients maintained some complaint, and 33.3% of patients maintained pain mainly in the form of diffuse pain even with regular treatment and monitoring. |
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Debbo, AlejandraSilva, Ângela Maria daPacheco, Roque de Almeida2020-03-17T20:32:56Z2020-03-17T20:32:56Z2019-08-23DEBBO, Alejandra. Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro. 2019. 77 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Sergipe, Aracaju, 2019.http://ri.ufs.br/jspui/handle/riufs/13062Chikungunya fever (CF) is an arbovirus caused by the chikungunya virus (CHIKV). Having as a main characteristic, joint pain and possible chronicity in more than half of infected patients. The purpose of the present study is to evaluate the persistent musculoskeletal manifestations of CF. These are a series of cases. It was evaluated a sample of 72 patients with persistent musculoskeletal disease (≥ 1 month) after the confirmation of CF by laboratory tests. These patients were monitored for 12 months and were treated at the ambulatory clinic of the University Hospital of the Federal University of Sergipe (HU / UFS). Patients were evaluated at admission, at 1 month, 2 months, and then every 3 months until 12 months. In all consultations, it was examined painful and / or swollen joints, periarticular symptoms, other important physical examination findings and VAS (visual analogue pain scale). Main results: 84.7% were female patients; the average age was 53.8 years; the average time of musculoskeletal complaints was 6 months. Comorbidities were present in 61.1% of patients and previous musculoskeletal disease was present in 69.4%. The most frequent presentation at admission was polyarticular in 76.4%. The most affected joints were: hands, knees, ankles and feet. VAS on admission was intense in most patients: 66.7%. Tenosynovitis was present in 44.5% of the patients, with ankles being more frequent. Corticosteroids were used in 65.3% of patients and chloroquine in 31.98%. It was concluded that persistent musculoskeletal manifestations after CF are frequent. After 12 months of monitoring, more than half of the patients maintained some complaint, and 33.3% of patients maintained pain mainly in the form of diffuse pain even with regular treatment and monitoring.A febre chikungunya (FC) é uma arbovirose causada pelo vírus chikungunya (CHIKV) e tem como característica principal a dor articular e a possível cronificação em mais da metade dos pacientes infectados. O objetivo do presente estudo é avaliar as manifestações musculo-esqueléticas persistentes da FC. Trata-se de uma série de casos. Foi avaliada uma amostra de 72 pacientes com quadro musculoesquelético persistente (≥ 1 mês) após FC confirmada por exames laboratoriais (PCR CHIKV e/ou IgM e/ou IgG CHIKV). Tais pacientes foram acompanhados por 12 meses e foram atendidos no ambulatório do Hospital Universitário da Universidade Federal de Sergipe (HU/UFS). Os pacientes foram avaliados na admissão e após um mês, dois meses e depois a cada três meses até completar os 12 meses. Em todas as consultas foram examinadas as articulações dolorosas e/ou edemaciadas, sintomas periarticulares, outros achados importantes no exame físico e a EVA (escala visual analógica de dor). Principais resultados: 84,7 % foram pacientes do sexo feminino; a idade média foi de 53,8 anos; o tempo médio de queixas musculoesquéleticas foi de seis meses. As comorbidades estiveram presentes em 61,1 % dos pacientes, e doença musculoesquelética prévia esteve presente em 69,4 %. A apresentação mais frequente na admissão foi a poliarticular em 76,4 %. As articulações mais acometidas foram: das mãos, joelhos, tornozelos e pés. A EVA na admissão foi intensa na maioria dos pacientes: 66,7 %. As tenossinovites estiveram presentes em 44,5 % dos pacientes e a de tornozelos foi a mais frequente. Os corticoesteroides foram utilizados em 65,3 % dos pacientes. Dentro dos DMRDs sintéticos, a cloroquina foi a mais utilizada em 31,98% dos pacientes. Concluiu-se que as manifestações musculoesqueléticas persistentes pós-FC são frequentes. Após 12 meses de acompanhamento mais da metade dos pacientes mantiveram alguma queixa sendo que 33,3% dos pacientes mativeram dor principalmente na forma de dor difusa, mesmo com tratamento e acompanhamento regular.AracajuporDor crônicaArbovirosesChikungunyaArtralgiaFebre chikungunyaArbovirusesArthralgiaChikungunya feverCIENCIAS DA SAUDEManifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiroPersistent musculoskeletal manifestations post- chikungunya fever: a series of cases in a state in northeast Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisPós-Graduação em Ciências da SaúdeUniversidade Federal de Sergipereponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTEXTALEJANDRA_DEBBO.pdf.txtALEJANDRA_DEBBO.pdf.txtExtracted texttext/plain127382https://ri.ufs.br/jspui/bitstream/riufs/13062/4/ALEJANDRA_DEBBO.pdf.txt4c8c1fec695c2581ed35a04b31339fcbMD54THUMBNAILALEJANDRA_DEBBO.pdf.jpgALEJANDRA_DEBBO.pdf.jpgGenerated Thumbnailimage/jpeg1251https://ri.ufs.br/jspui/bitstream/riufs/13062/5/ALEJANDRA_DEBBO.pdf.jpg7a30f563d9060f8c256bfc8a6f012761MD55LICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/13062/3/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD53ORIGINALALEJANDRA_DEBBO.pdfALEJANDRA_DEBBO.pdfapplication/pdf1599517https://ri.ufs.br/jspui/bitstream/riufs/13062/2/ALEJANDRA_DEBBO.pdf03bbacb56791684abb3ffcde989228c9MD52riufs/130622020-03-17 17:32:56.987oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2020-03-17T20:32:56Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.pt_BR.fl_str_mv |
Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro |
dc.title.alternative.eng.fl_str_mv |
Persistent musculoskeletal manifestations post- chikungunya fever: a series of cases in a state in northeast Brazil |
title |
Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro |
spellingShingle |
Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro Debbo, Alejandra Dor crônica Arboviroses Chikungunya Artralgia Febre chikungunya Arboviruses Arthralgia Chikungunya fever CIENCIAS DA SAUDE |
title_short |
Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro |
title_full |
Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro |
title_fullStr |
Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro |
title_full_unstemmed |
Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro |
title_sort |
Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro |
author |
Debbo, Alejandra |
author_facet |
Debbo, Alejandra |
author_role |
author |
dc.contributor.author.fl_str_mv |
Debbo, Alejandra |
dc.contributor.advisor1.fl_str_mv |
Silva, Ângela Maria da |
dc.contributor.advisor-co1.fl_str_mv |
Pacheco, Roque de Almeida |
contributor_str_mv |
Silva, Ângela Maria da Pacheco, Roque de Almeida |
dc.subject.por.fl_str_mv |
Dor crônica Arboviroses Chikungunya Artralgia Febre chikungunya |
topic |
Dor crônica Arboviroses Chikungunya Artralgia Febre chikungunya Arboviruses Arthralgia Chikungunya fever CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
Arboviruses Arthralgia Chikungunya fever |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Chikungunya fever (CF) is an arbovirus caused by the chikungunya virus (CHIKV). Having as a main characteristic, joint pain and possible chronicity in more than half of infected patients. The purpose of the present study is to evaluate the persistent musculoskeletal manifestations of CF. These are a series of cases. It was evaluated a sample of 72 patients with persistent musculoskeletal disease (≥ 1 month) after the confirmation of CF by laboratory tests. These patients were monitored for 12 months and were treated at the ambulatory clinic of the University Hospital of the Federal University of Sergipe (HU / UFS). Patients were evaluated at admission, at 1 month, 2 months, and then every 3 months until 12 months. In all consultations, it was examined painful and / or swollen joints, periarticular symptoms, other important physical examination findings and VAS (visual analogue pain scale). Main results: 84.7% were female patients; the average age was 53.8 years; the average time of musculoskeletal complaints was 6 months. Comorbidities were present in 61.1% of patients and previous musculoskeletal disease was present in 69.4%. The most frequent presentation at admission was polyarticular in 76.4%. The most affected joints were: hands, knees, ankles and feet. VAS on admission was intense in most patients: 66.7%. Tenosynovitis was present in 44.5% of the patients, with ankles being more frequent. Corticosteroids were used in 65.3% of patients and chloroquine in 31.98%. It was concluded that persistent musculoskeletal manifestations after CF are frequent. After 12 months of monitoring, more than half of the patients maintained some complaint, and 33.3% of patients maintained pain mainly in the form of diffuse pain even with regular treatment and monitoring. |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019-08-23 |
dc.date.accessioned.fl_str_mv |
2020-03-17T20:32:56Z |
dc.date.available.fl_str_mv |
2020-03-17T20:32:56Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
DEBBO, Alejandra. Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro. 2019. 77 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Sergipe, Aracaju, 2019. |
dc.identifier.uri.fl_str_mv |
http://ri.ufs.br/jspui/handle/riufs/13062 |
identifier_str_mv |
DEBBO, Alejandra. Manifestações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do Nordeste brasileiro. 2019. 77 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Sergipe, Aracaju, 2019. |
url |
http://ri.ufs.br/jspui/handle/riufs/13062 |
dc.language.iso.fl_str_mv |
por |
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por |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.program.fl_str_mv |
Pós-Graduação em Ciências da Saúde |
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Universidade Federal de Sergipe |
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