Chronic periodontitis and C-reactive protein levels

Detalhes bibliográficos
Autor(a) principal: Gomes Filho, Isaac Suzart
Data de Publicação: 2011
Outros Autores: Coelho, Julita Maria Freitas, Cruz, Simone Seixas da, Passos, Johelle Santana, Freitas, Camila Oliveira Teixeira de, Farias, Naiara Silva Aragão, Silva, Ruany Amorim da, Pereira, Milena Novais Silva, Lima, Thiago Lopes, Barreto, Mauricio Lima
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/3114
Resumo: Background: This study aims to analyze the relationship between chronic periodontitis and C-reactive protein (CRP)by considering associated variables in individuals with or without cardiovascular disease. Methods: A sample of 359 individuals of both sexes (aged ‡40 years) was assessed. Among these individuals, 144 subjects were admitted to the hospital because of a first occurrence of acute myocardial infarction; 80 subjects were in the hospital for reasons other than acute myocardial infarction; and 135 subjects were living in the community. A questionnaire was applied to obtain demographic and lifestyle characteristics. Complete clinical periodontal examinations and anthropometric assessments were performed. CRP levels, plasma glucose levels, lipid profiles, and blood tests were performed to investigate any conditions that might have suggested infection and/or inflammation. CRP evaluations were performed using nephelometry. Individuals were considered to have periodontal disease if they simultaneously presented at least four teeth with one or more sites with probing depth ‡4mm, clinical attachment loss ‡3 mm, and bleeding on probing. Procedures for descriptive analyses and logistic regression were used. Results: In the chronic periodontitis group, mean CRP levels were higher than those in the group without chronic periodontitis (2.6 – 2.6 mg/L versus 1.78 – 2.7 mg/L, respectively). The final model showed that individuals with chronic periodontitis were more likely to have high CRP levels (adjusted odds ratio: 2.26; 95% confidence interval: 1.30 to 3.93) considering the effects of age, schooling level, sex, smoking, high-density lipoprotein cholesterol, and diabetes. Conclusion: In this study, chronic periodontitis is associated with elevated plasma CRP levels, even after controlling for several potential confounders.
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spelling Gomes Filho, Isaac SuzartCoelho, Julita Maria FreitasCruz, Simone Seixas daPassos, Johelle SantanaFreitas, Camila Oliveira Teixeira deFarias, Naiara Silva AragãoSilva, Ruany Amorim daPereira, Milena Novais SilvaLima, Thiago LopesBarreto, Mauricio LimaGomes Filho, Isaac SuzartCoelho, Julita Maria FreitasCruz, Simone Seixas daPassos, Johelle SantanaFreitas, Camila Oliveira Teixeira deFarias, Naiara Silva AragãoSilva, Ruany Amorim daPereira, Milena Novais SilvaLima, Thiago LopesBarreto, Mauricio Lima2011-10-05T14:19:41Z2011-10-05T14:19:41Z20110022-3492http://www.repositorio.ufba.br/ri/handle/ri/3114v.82, n.7, p.969-978, 2011.Background: This study aims to analyze the relationship between chronic periodontitis and C-reactive protein (CRP)by considering associated variables in individuals with or without cardiovascular disease. Methods: A sample of 359 individuals of both sexes (aged ‡40 years) was assessed. Among these individuals, 144 subjects were admitted to the hospital because of a first occurrence of acute myocardial infarction; 80 subjects were in the hospital for reasons other than acute myocardial infarction; and 135 subjects were living in the community. A questionnaire was applied to obtain demographic and lifestyle characteristics. Complete clinical periodontal examinations and anthropometric assessments were performed. CRP levels, plasma glucose levels, lipid profiles, and blood tests were performed to investigate any conditions that might have suggested infection and/or inflammation. CRP evaluations were performed using nephelometry. Individuals were considered to have periodontal disease if they simultaneously presented at least four teeth with one or more sites with probing depth ‡4mm, clinical attachment loss ‡3 mm, and bleeding on probing. Procedures for descriptive analyses and logistic regression were used. Results: In the chronic periodontitis group, mean CRP levels were higher than those in the group without chronic periodontitis (2.6 – 2.6 mg/L versus 1.78 – 2.7 mg/L, respectively). The final model showed that individuals with chronic periodontitis were more likely to have high CRP levels (adjusted odds ratio: 2.26; 95% confidence interval: 1.30 to 3.93) considering the effects of age, schooling level, sex, smoking, high-density lipoprotein cholesterol, and diabetes. Conclusion: In this study, chronic periodontitis is associated with elevated plasma CRP levels, even after controlling for several potential confounders.Submitted by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2011-10-05T14:19:38Z No. of bitstreams: 1 Per int 2011.15.pdf: 503373 bytes, checksum: f6cf8609309010369d9251ffc5ecebd8 (MD5)Made available in DSpace on 2011-10-05T14:19:41Z (GMT). No. of bitstreams: 1 Per int 2011.15.pdf: 503373 bytes, checksum: f6cf8609309010369d9251ffc5ecebd8 (MD5) Previous issue date: 2011IndianapolisC-reactive proteinInflammationMyocardial InfarctionPeriodontitisChronic periodontitis and C-reactive protein levelsJ Periodontolinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINALPer int 2011.15.pdfPer int 2011.15.pdfapplication/pdf503373https://repositorio.ufba.br/bitstream/ri/3114/1/Per%20int%202011.15.pdff6cf8609309010369d9251ffc5ecebd8MD51LICENSElicense.txtlicense.txttext/plain1907https://repositorio.ufba.br/bitstream/ri/3114/2/license.txtef13384d84cd104ddf6bd3d80c1265aaMD52TEXTPer int 2011.15.pdf.txtPer int 2011.15.pdf.txtExtracted texttext/plain41256https://repositorio.ufba.br/bitstream/ri/3114/3/Per%20int%202011.15.pdf.txt96843678d324f5fca0ee7ad36a5a6b96MD53ri/31142022-07-05 14:03:14.614oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:14Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Chronic periodontitis and C-reactive protein levels
dc.title.alternative.pt_BR.fl_str_mv J Periodontol
title Chronic periodontitis and C-reactive protein levels
spellingShingle Chronic periodontitis and C-reactive protein levels
Gomes Filho, Isaac Suzart
C-reactive protein
Inflammation
Myocardial Infarction
Periodontitis
title_short Chronic periodontitis and C-reactive protein levels
title_full Chronic periodontitis and C-reactive protein levels
title_fullStr Chronic periodontitis and C-reactive protein levels
title_full_unstemmed Chronic periodontitis and C-reactive protein levels
title_sort Chronic periodontitis and C-reactive protein levels
author Gomes Filho, Isaac Suzart
author_facet Gomes Filho, Isaac Suzart
Coelho, Julita Maria Freitas
Cruz, Simone Seixas da
Passos, Johelle Santana
Freitas, Camila Oliveira Teixeira de
Farias, Naiara Silva Aragão
Silva, Ruany Amorim da
Pereira, Milena Novais Silva
Lima, Thiago Lopes
Barreto, Mauricio Lima
author_role author
author2 Coelho, Julita Maria Freitas
Cruz, Simone Seixas da
Passos, Johelle Santana
Freitas, Camila Oliveira Teixeira de
Farias, Naiara Silva Aragão
Silva, Ruany Amorim da
Pereira, Milena Novais Silva
Lima, Thiago Lopes
Barreto, Mauricio Lima
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gomes Filho, Isaac Suzart
Coelho, Julita Maria Freitas
Cruz, Simone Seixas da
Passos, Johelle Santana
Freitas, Camila Oliveira Teixeira de
Farias, Naiara Silva Aragão
Silva, Ruany Amorim da
Pereira, Milena Novais Silva
Lima, Thiago Lopes
Barreto, Mauricio Lima
Gomes Filho, Isaac Suzart
Coelho, Julita Maria Freitas
Cruz, Simone Seixas da
Passos, Johelle Santana
Freitas, Camila Oliveira Teixeira de
Farias, Naiara Silva Aragão
Silva, Ruany Amorim da
Pereira, Milena Novais Silva
Lima, Thiago Lopes
Barreto, Mauricio Lima
dc.subject.por.fl_str_mv C-reactive protein
Inflammation
Myocardial Infarction
Periodontitis
topic C-reactive protein
Inflammation
Myocardial Infarction
Periodontitis
description Background: This study aims to analyze the relationship between chronic periodontitis and C-reactive protein (CRP)by considering associated variables in individuals with or without cardiovascular disease. Methods: A sample of 359 individuals of both sexes (aged ‡40 years) was assessed. Among these individuals, 144 subjects were admitted to the hospital because of a first occurrence of acute myocardial infarction; 80 subjects were in the hospital for reasons other than acute myocardial infarction; and 135 subjects were living in the community. A questionnaire was applied to obtain demographic and lifestyle characteristics. Complete clinical periodontal examinations and anthropometric assessments were performed. CRP levels, plasma glucose levels, lipid profiles, and blood tests were performed to investigate any conditions that might have suggested infection and/or inflammation. CRP evaluations were performed using nephelometry. Individuals were considered to have periodontal disease if they simultaneously presented at least four teeth with one or more sites with probing depth ‡4mm, clinical attachment loss ‡3 mm, and bleeding on probing. Procedures for descriptive analyses and logistic regression were used. Results: In the chronic periodontitis group, mean CRP levels were higher than those in the group without chronic periodontitis (2.6 – 2.6 mg/L versus 1.78 – 2.7 mg/L, respectively). The final model showed that individuals with chronic periodontitis were more likely to have high CRP levels (adjusted odds ratio: 2.26; 95% confidence interval: 1.30 to 3.93) considering the effects of age, schooling level, sex, smoking, high-density lipoprotein cholesterol, and diabetes. Conclusion: In this study, chronic periodontitis is associated with elevated plasma CRP levels, even after controlling for several potential confounders.
publishDate 2011
dc.date.accessioned.fl_str_mv 2011-10-05T14:19:41Z
dc.date.available.fl_str_mv 2011-10-05T14:19:41Z
dc.date.issued.fl_str_mv 2011
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dc.identifier.issn.none.fl_str_mv 0022-3492
dc.identifier.number.pt_BR.fl_str_mv v.82, n.7, p.969-978, 2011.
identifier_str_mv 0022-3492
v.82, n.7, p.969-978, 2011.
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