Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2007 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/15980 |
Resumo: | Texto completo: acesso restrito. p. 1163-1170 |
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Bailie, George R.Elder, Stacey J.Mason, Nancy A.Asano, YasushiCruz, José MiguelFukuhara, ShunichiLopes, Antonio Alberto da SilvaMapes, Donna L.Mendelssohn, David C.Bommer, JuergenYoung, Eric W.Bailie, George R.Elder, Stacey J.Mason, Nancy A.Asano, YasushiCruz, José MiguelFukuhara, ShunichiLopes, Antonio Alberto da SilvaMapes, Donna L.Mendelssohn, David C.Bommer, JuergenYoung, Eric W.2014-09-09T15:59:36Z20070931-0509http://repositorio.ufba.br/ri/handle/ri/15980v. 22, n. 4Texto completo: acesso restrito. p. 1163-1170Background. The relationship between medication prescription and sexual dysfunction (SD) in dialysis patients is unclear. Methods. We studied antihypertensive and antidepressive agents prescribed for 7346 patients in the Dialysis Outcomes and Practice Patterns Study phase 1 (DOPPS I) and 8891 patients in DOPPS II. At baseline, DOPPS I patients completed a quality of life survey, including four questions about sexual functioning, from which we created a composite SD scale. DOPPS II patients were asked only one question about SD. We examined predictors of SD with logistic regression, using numerous patient characteristics, comorbid conditions and additional variables. Results. Reported SD ranged from 66.4% (France) to 84.5% (Spain). The mean composite SD score ranged from 6.4 (Spain) to 7.9 (Germany) (on a 3–15 scale). Peripheral α-blockers increased odds of DOPPS I patients having their sex life bothered by end-stage renal disease (ESRD) (OR = 1.18), and there were elevated odds of arousal problems with central antagonists, loop diuretics and peripheral α-blockers (OR = 1.19, 1.24 and 1.29, respectively). Selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines increased odds of problems with enjoyment (OR = 1.59 and 1.26, respectively) and arousal (OR = 1.70 and 1.24, respectively), and having sex life bothered by ESRD (DOPPS I: OR = 1.36 and 1.24; DOPPS II: 1.30 and 1.31, respectively). Vasodilators reduced the odds of sexual enjoyment problems (OR = 0.75). Composite SD scores worsened with peripheral α-blockers (+0.41), tricyclics (+0.78), SSRIs (+0.80) and benzodiazepines (+0.50), but not with vasodilators (−0.57). Conclusions. Awareness of associations between SD and prescribed medications may offer opportunities for intervention.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-31T14:34:16Z No. of bitstreams: 1 10.1093ndt-gfl755.pdf: 130083 bytes, checksum: 014945e9814db5d9f30b3ea19c220423 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T15:59:36Z (GMT) No. of bitstreams: 1 10.1093ndt-gfl755.pdf: 130083 bytes, checksum: 014945e9814db5d9f30b3ea19c220423 (MD5)Made available in DSpace on 2014-09-09T15:59:36Z (GMT). No. of bitstreams: 1 10.1093ndt-gfl755.pdf: 130083 bytes, checksum: 014945e9814db5d9f30b3ea19c220423 (MD5) Previous issue date: 2007http://dx.doi.org/10.1093/ndt/gfl755reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAntidepressivesAntihypertensive agentsHaemodialysisMedication-relatedSexual dysfunctionSexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPSNephrology Dialysis Transplantationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL10.1093ndt-gfl755.pdf10.1093ndt-gfl755.pdfapplication/pdf130083https://repositorio.ufba.br/bitstream/ri/15980/1/10.1093ndt-gfl755.pdf014945e9814db5d9f30b3ea19c220423MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15980/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT10.1093ndt-gfl755.pdf.txt10.1093ndt-gfl755.pdf.txtExtracted texttext/plain40111https://repositorio.ufba.br/bitstream/ri/15980/3/10.1093ndt-gfl755.pdf.txte8ed398ac21ac980f6f4125c28dd696cMD53ri/159802022-08-08 13:17:35.14oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:35Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS |
| dc.title.alternative.pt_BR.fl_str_mv |
Nephrology Dialysis Transplantation |
| title |
Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS |
| spellingShingle |
Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS Bailie, George R. Antidepressives Antihypertensive agents Haemodialysis Medication-related Sexual dysfunction |
| title_short |
Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS |
| title_full |
Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS |
| title_fullStr |
Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS |
| title_full_unstemmed |
Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS |
| title_sort |
Sexual dysfunction in dialysis patients treated with antihypertensive or antidepressive medications: results from the DOPPS |
| author |
Bailie, George R. |
| author_facet |
Bailie, George R. Elder, Stacey J. Mason, Nancy A. Asano, Yasushi Cruz, José Miguel Fukuhara, Shunichi Lopes, Antonio Alberto da Silva Mapes, Donna L. Mendelssohn, David C. Bommer, Juergen Young, Eric W. |
| author_role |
author |
| author2 |
Elder, Stacey J. Mason, Nancy A. Asano, Yasushi Cruz, José Miguel Fukuhara, Shunichi Lopes, Antonio Alberto da Silva Mapes, Donna L. Mendelssohn, David C. Bommer, Juergen Young, Eric W. |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Bailie, George R. Elder, Stacey J. Mason, Nancy A. Asano, Yasushi Cruz, José Miguel Fukuhara, Shunichi Lopes, Antonio Alberto da Silva Mapes, Donna L. Mendelssohn, David C. Bommer, Juergen Young, Eric W. Bailie, George R. Elder, Stacey J. Mason, Nancy A. Asano, Yasushi Cruz, José Miguel Fukuhara, Shunichi Lopes, Antonio Alberto da Silva Mapes, Donna L. Mendelssohn, David C. Bommer, Juergen Young, Eric W. |
| dc.subject.por.fl_str_mv |
Antidepressives Antihypertensive agents Haemodialysis Medication-related Sexual dysfunction |
| topic |
Antidepressives Antihypertensive agents Haemodialysis Medication-related Sexual dysfunction |
| description |
Texto completo: acesso restrito. p. 1163-1170 |
| publishDate |
2007 |
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2007 |
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2014-09-09T15:59:36Z |
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info:eu-repo/semantics/publishedVersion |
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0931-0509 |
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v. 22, n. 4 |
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0931-0509 v. 22, n. 4 |
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