Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/16641 |
Resumo: | Texto completo: acesso restrito. p. 69-73 |
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Machado, Paulo Roberto LimaAraújo, CibeleSilva, Andréa T. daAlmeida, Roque Pacheco deD'Oliveira Junior, ArgemiroBittencourt, Achilea Candida LisboaCarvalho Filho, Edgar Marcelino deMachado, Paulo Roberto LimaAraújo, CibeleSilva, Andréa T. daAlmeida, Roque Pacheco deD'Oliveira Junior, ArgemiroBittencourt, Achilea Candida LisboaCarvalho Filho, Edgar Marcelino de2014-11-21T13:50:43Z20021058-4838http://repositorio.ufba.br/ri/handle/ri/16641v. 34, n. 12Texto completo: acesso restrito. p. 69-73The clinical characteristics and treatment outcome were determined for 26 patients who presented with early-stage cutaneous leishmaniasis. Illness duration ranged from 8 to 20 days, and the commonest clinical presentation was the presence of a papule with small central crust on a lower extremity. Prominent regional adenopathy was found in 22 (85%) of 26 patients. The results of an intradermal skin test for Leishmania were positive for 96% of those patients, and results of serologic testing were positive for 61% of patients tested. Ten (46%) of 22 patients for whom follow-up data were available developed enlargement and ulceration of the lesion despite early antimony therapy and required additional courses of treatment. Histopathological studies of samples from the lesions of 3 patients showed vasculitis. These data show that early therapy for cutaneous leishmaniasis does not prevent the development of an ulcer in one-half of patients. This unfavorable outcome underlines the relevance of local exacerbated inflammatory and immune response in the pathogenesis of the disease.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-01-20T12:55:22Z No. of bitstreams: 1 Paulo Machado.pdf: 283941 bytes, checksum: 8a820425f50c84a4911718fdbc9636f6 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-11-21T13:50:43Z (GMT) No. of bitstreams: 1 Paulo Machado.pdf: 283941 bytes, checksum: 8a820425f50c84a4911718fdbc9636f6 (MD5)Made available in DSpace on 2014-11-21T13:50:43Z (GMT). No. of bitstreams: 1 Paulo Machado.pdf: 283941 bytes, checksum: 8a820425f50c84a4911718fdbc9636f6 (MD5) Previous issue date: 2002http://dx.doi.org/ 10.1086/340526reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALeishmaniasis, CutaneousUlcerFailure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcerClinical Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengLICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16641/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52ORIGINALPaulo Machado.pdfPaulo Machado.pdfapplication/pdf283941https://repositorio.ufba.br/bitstream/ri/16641/1/Paulo%20Machado.pdf8a820425f50c84a4911718fdbc9636f6MD51TEXTPaulo Machado.pdf.txtPaulo Machado.pdf.txtExtracted texttext/plain20655https://repositorio.ufba.br/bitstream/ri/16641/3/Paulo%20Machado.pdf.txt03b1ba0bb0aaeeb2ba28549d58649a8eMD53ri/166412022-07-05 14:03:44.014oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:44Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer |
dc.title.alternative.pt_BR.fl_str_mv |
Clinical Infectious Diseases |
title |
Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer |
spellingShingle |
Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer Machado, Paulo Roberto Lima Leishmaniasis, Cutaneous Ulcer |
title_short |
Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer |
title_full |
Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer |
title_fullStr |
Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer |
title_full_unstemmed |
Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer |
title_sort |
Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer |
author |
Machado, Paulo Roberto Lima |
author_facet |
Machado, Paulo Roberto Lima Araújo, Cibele Silva, Andréa T. da Almeida, Roque Pacheco de D'Oliveira Junior, Argemiro Bittencourt, Achilea Candida Lisboa Carvalho Filho, Edgar Marcelino de |
author_role |
author |
author2 |
Araújo, Cibele Silva, Andréa T. da Almeida, Roque Pacheco de D'Oliveira Junior, Argemiro Bittencourt, Achilea Candida Lisboa Carvalho Filho, Edgar Marcelino de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Machado, Paulo Roberto Lima Araújo, Cibele Silva, Andréa T. da Almeida, Roque Pacheco de D'Oliveira Junior, Argemiro Bittencourt, Achilea Candida Lisboa Carvalho Filho, Edgar Marcelino de Machado, Paulo Roberto Lima Araújo, Cibele Silva, Andréa T. da Almeida, Roque Pacheco de D'Oliveira Junior, Argemiro Bittencourt, Achilea Candida Lisboa Carvalho Filho, Edgar Marcelino de |
dc.subject.por.fl_str_mv |
Leishmaniasis, Cutaneous Ulcer |
topic |
Leishmaniasis, Cutaneous Ulcer |
description |
Texto completo: acesso restrito. p. 69-73 |
publishDate |
2002 |
dc.date.issued.fl_str_mv |
2002 |
dc.date.accessioned.fl_str_mv |
2014-11-21T13:50:43Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufba.br/ri/handle/ri/16641 |
dc.identifier.issn.none.fl_str_mv |
1058-4838 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 34, n. 12 |
identifier_str_mv |
1058-4838 v. 34, n. 12 |
url |
http://repositorio.ufba.br/ri/handle/ri/16641 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.rights.driver.fl_str_mv |
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openAccess |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/ 10.1086/340526 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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