Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region

Detalhes bibliográficos
Autor(a) principal: Carvalho, Cristiana Maria Costa Nascimento de
Data de Publicação: 2011
Outros Autores: Cardoso, Maria Regina Alves, Ruuskanen, Olli, Lappalainen, Maija
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/14810
Resumo: Texto completo: acesso restrito. p. 285–287
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spelling Carvalho, Cristiana Maria Costa Nascimento deCardoso, Maria Regina AlvesRuuskanen, OlliLappalainen, MaijaCarvalho, Cristiana Maria Costa Nascimento deCardoso, Maria Regina AlvesRuuskanen, OlliLappalainen, Maija2014-04-09T13:40:26Z20111750-2640http://repositorio.ufba.br/ri/handle/ri/14810v. 5, n. 4Texto completo: acesso restrito. p. 285–287Background  Limited information is available on the role of human metapneumovirus (HMPV) as the unique pathogen among children hospitalized for community-acquired pneumonia (CAP) in a tropical region. Objective  We aimed to describe HMPV infection among children with CAP investigating bacterial and viral co-infections. Patients and methods  A prospective study was carried out in Salvador, North-East Brazil. Overall, 268 children aged <5 years hospitalized for CAP were enrolled. Human metapneumovirus RNA was detected in nasopharyngeal aspirates (NPA) by reverse transcription polymerase chain reaction. Sixteen other bacterial and viral pathogens were investigated by an expanded panel of laboratory methods. Chest X-ray taken on admission was read by an independent paediatric radiologist unaware of clinical information or the established aetiology. Results  Human metapneumovirus RNA was detected in NPAs of 11 (4.1%) children, of which 4 (36%) had sole HMPV infection. The disease was significantly shorter among patients with sole HMPV infection in comparison with patients with mixed infection (4 ± 1 versus 7 ± 2 days, P = 0.03). Three of those four patients had alveolar infiltrates. Conclusion  Sole HMPV infection was detected in children with CAP in Salvador, North-East Brazil. HMPV may play a role in the childhood CAP burden.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-03-18T16:54:50Z No. of bitstreams: 1 Cristiana M. Nascimento Carvalho.pdf: 59712 bytes, checksum: 05ca7afc77eb8befe163c04273bfbde3 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-04-09T13:40:26Z (GMT) No. of bitstreams: 1 Cristiana M. Nascimento Carvalho.pdf: 59712 bytes, checksum: 05ca7afc77eb8befe163c04273bfbde3 (MD5)Made available in DSpace on 2014-04-09T13:40:26Z (GMT). No. of bitstreams: 1 Cristiana M. 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dc.title.pt_BR.fl_str_mv Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region
dc.title.alternative.pt_BR.fl_str_mv Influenza and Other Respiratory Viruses
title Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region
spellingShingle Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region
Carvalho, Cristiana Maria Costa Nascimento de
Acute respiratory infection
Lower tract respiratory infection
New respiratory virus
Respiratory viral infection
title_short Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region
title_full Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region
title_fullStr Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region
title_full_unstemmed Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region
title_sort Sole infection by human metapneumovirus among children with radiographically diagnosed community-acquired pneumonia in a tropical region
author Carvalho, Cristiana Maria Costa Nascimento de
author_facet Carvalho, Cristiana Maria Costa Nascimento de
Cardoso, Maria Regina Alves
Ruuskanen, Olli
Lappalainen, Maija
author_role author
author2 Cardoso, Maria Regina Alves
Ruuskanen, Olli
Lappalainen, Maija
author2_role author
author
author
dc.contributor.author.fl_str_mv Carvalho, Cristiana Maria Costa Nascimento de
Cardoso, Maria Regina Alves
Ruuskanen, Olli
Lappalainen, Maija
Carvalho, Cristiana Maria Costa Nascimento de
Cardoso, Maria Regina Alves
Ruuskanen, Olli
Lappalainen, Maija
dc.subject.por.fl_str_mv Acute respiratory infection
Lower tract respiratory infection
New respiratory virus
Respiratory viral infection
topic Acute respiratory infection
Lower tract respiratory infection
New respiratory virus
Respiratory viral infection
description Texto completo: acesso restrito. p. 285–287
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2014-04-09T13:40:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/14810
dc.identifier.issn.none.fl_str_mv 1750-2640
dc.identifier.number.pt_BR.fl_str_mv v. 5, n. 4
identifier_str_mv 1750-2640
v. 5, n. 4
url http://repositorio.ufba.br/ri/handle/ri/14810
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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