Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G

Detalhes bibliográficos
Autor(a) principal: Simbalista, Raquel
Data de Publicação: 2011
Outros Autores: Araújo, Marcelo, Carvalho, Cristiana Maria Costa Nascimento de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/2877
Resumo: p.95-100
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spelling Simbalista, RaquelAraújo, MarceloCarvalho, Cristiana Maria Costa Nascimento deSimbalista, RaquelAraújo, MarceloCarvalho, Cristiana Maria Costa Nascimento de2011-09-26T19:13:05Z2011-09-26T19:13:05Z20111807-5932http://www.repositorio.ufba.br/ri/handle/ri/2877v.66, n.1p.95-100OBJECTIVE: To describe the evolution and outcome of children hospitalized with community-acquired pneumonia receiving penicillin. METHODS: A search was carried out for all hospitalized community-acquired pneumonia cases in a 37-month period. Inclusion criteria comprised age >2 months, intravenous penicillin G use at 200,000 IU/kg/day for >48 h and chest x-ray results. Confounders leading to exclusion included underlying debilitating or chronic pulmonary illnesses, nosocomial pneumonia or transference to another hospital. Pneumonia was confirmed if a pulmonary infiltrate or pleural effusion was described by an independent radiologist blind to the clinical information. Data on admission and evolution were entered on a standardized form. RESULTS: Of 154 studied cases, 123 (80%) and 40 (26%) had pulmonary infiltrate or pleural effusion, respectively. Penicilli was substituted by other antibiotics in 28 (18%) patients, in whom the sole significant decrease was in the frequency of tachypnea from the first to the second day of treatment (86% vs. 50%, p = 0.008). Among patients treated exclusively with penicillin G, fever (46% vs. 26%, p = 0.002), tachypnea (74% vs. 59%, p = 0.003), chest indrawing (29% vs. 13%, p<0.001) and nasal flaring (10% vs. 1.6%, p = 0.001) frequencies significantly decreased from admission to the first day of treatment. Patients treated with other antimicrobial agents stayed longer in the hospital than those treated solely with penicillin G (16±6 vs. 8±4 days, p<0.001, mean difference (95% confidence interval) 8 (6–10)). None of the studied patients died. CONCLUSION: Penicillin G successfSubmitted by Rigaud Andréa (andrearigaud16@yahoo.com.br) on 2011-09-26T19:13:05Z No. of bitstreams: 1 v66n1a17.pdf: 242554 bytes, checksum: 3c43ebf6146139f2890d6e58aa705bfb (MD5)Made available in DSpace on 2011-09-26T19:13:05Z (GMT). No. of bitstreams: 1 v66n1a17.pdf: 242554 bytes, checksum: 3c43ebf6146139f2890d6e58aa705bfb (MD5) Previous issue date: 2011São PauloFaculdade de Medicina / USPAcute respiratory infectionAntibioticBeta-lactamsLower respiratory tract infectionTreatment successOutcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin GClinicsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINALv66n1a17.pdfv66n1a17.pdfapplication/pdf242554https://repositorio.ufba.br/bitstream/ri/2877/1/v66n1a17.pdf3c43ebf6146139f2890d6e58aa705bfbMD51LICENSElicense.txtlicense.txttext/plain1906https://repositorio.ufba.br/bitstream/ri/2877/2/license.txt3dc29c76dc8909f33a0dee88b39b06c0MD52TEXTv66n1a17.pdf.txtv66n1a17.pdf.txtExtracted texttext/plain25606https://repositorio.ufba.br/bitstream/ri/2877/3/v66n1a17.pdf.txt7465d7293f460e745f2f859ad2f4d5a5MD53ri/28772022-07-05 14:03:06.472oai:repositorio.ufba.br:ri/2877TGljZW5zZSBncmFudGVkIGJ5IFJpZ2F1ZCBBbmRyw6lhIChhbmRyZWFyaWdhdWQxNkB5YWhvby5jb20uYnIpIG9uIDIwMTEtMDktMjZUMTk6MTM6MDVaIChHTVQpOgoKVGVybW8gZGUgTGljZW7Dp2EsIG7Do28gZXhjbHVzaXZvLCBwYXJhIG8gZGVww7NzaXRvIG5vIApyZXBvc2l0w7NyaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBCgogICAgUGVsbyBwcm9jZXNzbyBkZSBzdWJtaXNzw6NvIGRlIGRvY3VtZW50b3MsIG8gYXV0b3Igb3Ugc2V1CnJlcHJlc2VudGFudGUgbGVnYWwsIGFvIGFjZWl0YXIgZXNzZSB0ZXJtbyBkZSBsaWNlbsOnYSwgY29uY2VkZSBhbwpSZXBvc2l0w7NyaW8gSW5zdGl0dWNpb25hbCBkYSBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkYSBCYWhpYSBvIGRpcmVpdG8KZGUgbWFudGVyIHVtYSBjw7NwaWEgZW0gc2V1IHJlcG9zaXTDs3JpbyBjb20gYSBmaW5hbGlkYWRlLCBwcmltZWlyYSwgCmRlIHByZXNlcnZhw6fDo28uIEVzc2UgdGVybW8sIG7Do28gZXhjbHVzaXZvLCBtYW50w6ptIG9zIGRpcmVpdG9zIGRlIAphdXRvci9jb3B5cmlnaHQsIG1hcyBlbnRlbmRlIG8gZG9jdW1lbnRvIGNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsCiBkZXNzYSBVbml2ZXJzaWRhZGUuIAoKICAgIFBhcmEgb3MgZG9jdW1lbnRvcyBwdWJsaWNhZG9zIGNvbSByZXBhc3NlIGRlIGRpcmVpdG9zIGRlIApkaXN0cmlidWnDp8OjbywgZXNzZSB0ZXJtbyBkZSBsaWNlbsOnYSBlbnRlbmRlIHF1ZTogCgogICAgTWFudGVuZG8gb3PCoCBkaXJlaXRvcyBhdXRvcmFpcywgcmVwYXNzYWRvcyBhIHRlcmNlaXJvcywgZW0gY2FzbyAKZGUgcHVibGljYcOnw7VlcywgbyByZXBvc2l0w7NyaW8gcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIAppbnRlZ3JhbCwgbWFzIGxpYmVyYSBhcyBpbmZvcm1hw6fDtWVzIHNvYnJlIG8gZG9jdW1lbnRvIChNZXRhZGFkb3MgZGVzY3JpdGl2b3MpLgogRGVzdGEgZm9ybWEsIGF0ZW5kZW5kbyBhb3MgYW5zZWlvcyBkZXNzYSB1bml2ZXJzaWRhZGUgCmVtIG1hbnRlciBzdWEgcHJvZHXDp8OjbyBjaWVudMOtwq1maWNhIGNvbSBhcyByZXN0cmnDp8O1ZXMgaW1wb3N0YXMgcGVsb3MgCmVkaXRvcmVzIGRlIHBlcmnDs2RpY29zLiAKCiAgICBQYXJhIGFzIHB1YmxpY2HDp8O1ZXMgZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbMOtwq10aWNhIGRlIApBY2Vzc28gQWJlcnRvLCBvcyBkZXDDs3NpdG9zIGNvbXB1bHPDs3Jpb3MgbmVzc2UgcmVwb3NpdMOzcmlvIG1hbnTDqm0gCm9zIGRpcmVpdG9zIGF1dG9yYWlzLCBtYXMgbWFudMOqbSBvIGFjZXNzbyBpcnJlc3RyaXRvIGFvIG1ldGFkYWRvcyAKZSB0ZXh0byBjb21wbGV0by4gQXNzaW0sIGEgYWNlaXRhw6fDo28gZGVzc2UgdGVybW8gbsOjbyBuZWNlc3NpdGEgZGUgCmNvbnNlbnRpbWVudG8gcG9yIHBhcnRlIGRlIGF1dG9yZXMvZGV0ZW50b3JlcyBkb3MgZGlyZWl0b3MsIHBvciAKZXN0YXJlbSBlbSBpbmljaWF0aXZhcyBkZSBhY2Vzc28gYWJlcnRvLgoKICAgIEVtIGFtYm9zIG8gY2FzbywgZXNzZSB0ZXJtbyBkZSBsaWNlbsOnYSwgcG9kZSBzZXIgYWNlaXRvIHBlbG8gCmF1dG9yLCBkZXRlbnRvcmVzIGRlIGRpcmVpdG9zIGUvb3UgdGVyY2Vpcm9zIGFtcGFyYWRvcyBwZWxhIAp1bml2ZXJzaWRhZGUuIERldmlkbyBhb3MgZGlmZXJlbnRlcyBwcm9jZXNzb3MgcGVsbyBxdWFsIGEgc3VibWlzc8OjbyAKcG9kZSBvY29ycmVyLCBvIHJlcG9zaXTDs3JpbyBwZXJtaXRlIGEgYWNlaXRhw6fDo28gZGEgbGljZW7Dp2EgcG9yIAp0ZXJjZWlyb3MsIHNvbWVudGUgbm9zIGNhc29zIGRlIGRvY3VtZW50b3MgcHJvZHV6aWRvcyBwb3IgaW50ZWdyYW50ZXMgCmRhIFVGQkEgZSBzdWJtZXRpZG9zIHBvciBwZXNzb2FzIGFtcGFyYWRhcyBwb3IgZXN0YSBpbnN0aXR1acOnw6NvCg==Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:06Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G
dc.title.alternative.pt_BR.fl_str_mv Clinics
title Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G
spellingShingle Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G
Simbalista, Raquel
Acute respiratory infection
Antibiotic
Beta-lactams
Lower respiratory tract infection
Treatment success
title_short Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G
title_full Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G
title_fullStr Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G
title_full_unstemmed Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G
title_sort Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G
author Simbalista, Raquel
author_facet Simbalista, Raquel
Araújo, Marcelo
Carvalho, Cristiana Maria Costa Nascimento de
author_role author
author2 Araújo, Marcelo
Carvalho, Cristiana Maria Costa Nascimento de
author2_role author
author
dc.contributor.author.fl_str_mv Simbalista, Raquel
Araújo, Marcelo
Carvalho, Cristiana Maria Costa Nascimento de
Simbalista, Raquel
Araújo, Marcelo
Carvalho, Cristiana Maria Costa Nascimento de
dc.subject.por.fl_str_mv Acute respiratory infection
Antibiotic
Beta-lactams
Lower respiratory tract infection
Treatment success
topic Acute respiratory infection
Antibiotic
Beta-lactams
Lower respiratory tract infection
Treatment success
description p.95-100
publishDate 2011
dc.date.accessioned.fl_str_mv 2011-09-26T19:13:05Z
dc.date.available.fl_str_mv 2011-09-26T19:13:05Z
dc.date.issued.fl_str_mv 2011
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/2877
dc.identifier.issn.none.fl_str_mv 1807-5932
dc.identifier.number.pt_BR.fl_str_mv v.66, n.1
identifier_str_mv 1807-5932
v.66, n.1
url http://www.repositorio.ufba.br/ri/handle/ri/2877
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Faculdade de Medicina / USP
publisher.none.fl_str_mv Faculdade de Medicina / USP
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/2877/1/v66n1a17.pdf
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