Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts

Detalhes bibliográficos
Autor(a) principal: Andrade, Zilton de Araújo
Data de Publicação: 2003
Outros Autores: Reis, Sílvia Regina A., Pugliese, Lívia Souza, Medrado, Alena Ribeiro Alves Peixoto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/14313
Resumo: Texto completo: acesso restrito. p. 239–244
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spelling Andrade, Zilton de AraújoReis, Sílvia Regina A.Pugliese, Lívia SouzaMedrado, Alena Ribeiro Alves PeixotoAndrade, Zilton de AraújoReis, Sílvia Regina A.Pugliese, Lívia SouzaMedrado, Alena Ribeiro Alves Peixoto2014-01-10T16:21:08Z20030196-8092http://repositorio.ufba.br/ri/handle/ri/14313Texto completo: acesso restrito. p. 239–244Background and Objective In re-evaluating the effects of laser therapy in wound healing, the role of extracellular matrix elements and myofibroblasts, was analyzed. Study Design/Materials and Methods Cutaneous wounds were inflicted on the back of 72 Wistar rats. Low level laser was locally applied with different energy densities. Lesions were analyzed after 24, 48, 72 hours and 5, 7, and 14 days. Tissues were studied by histology, immunohistochemistry, and electron microscopy. Results In treated animals, the extent of edema and the number of inflammatory cells were reduced (P < 0.05), but the amount of collagen and elastic fibers appeared slightly increased. Desmin/smooth muscle alpha-actin-phenotype myofibroblasts were statistically more prominent on the 3rd day after surgery (P < 0.05) in treated wounds than in controls. Treatment with a dosage of 4 J/cm2 was superior to that with 8 J/cm2. Conclusions Laser therapy reduced the inflammatory reaction, induced increased collagen deposition and a greater proliferation of myofibroblasts in experimental cutaneous wounds.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-01-10T12:26:09Z No. of bitstreams: 1 Zilton A. Andrade.pdf: 222117 bytes, checksum: c582b9bf0b0630a6235753c6c405f53f (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-01-10T16:21:08Z (GMT) No. of bitstreams: 1 Zilton A. Andrade.pdf: 222117 bytes, checksum: c582b9bf0b0630a6235753c6c405f53f (MD5)Made available in DSpace on 2014-01-10T16:21:08Z (GMT). No. of bitstreams: 1 Zilton A. Andrade.pdf: 222117 bytes, checksum: c582b9bf0b0630a6235753c6c405f53f (MD5) Previous issue date: 2003http://dx.doi.org/ 10.1002/lsm.10126reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBABiostimulationLow-level laserSkin woundsInfluence of low level laser therapy on wound healing and its biological action upon myofibroblastsLasers in Surgery and Medicineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALZilton A. Andrade.pdfZilton A. 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dc.title.pt_BR.fl_str_mv Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts
dc.title.alternative.pt_BR.fl_str_mv Lasers in Surgery and Medicine
title Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts
spellingShingle Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts
Andrade, Zilton de Araújo
Biostimulation
Low-level laser
Skin wounds
title_short Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts
title_full Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts
title_fullStr Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts
title_full_unstemmed Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts
title_sort Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts
author Andrade, Zilton de Araújo
author_facet Andrade, Zilton de Araújo
Reis, Sílvia Regina A.
Pugliese, Lívia Souza
Medrado, Alena Ribeiro Alves Peixoto
author_role author
author2 Reis, Sílvia Regina A.
Pugliese, Lívia Souza
Medrado, Alena Ribeiro Alves Peixoto
author2_role author
author
author
dc.contributor.author.fl_str_mv Andrade, Zilton de Araújo
Reis, Sílvia Regina A.
Pugliese, Lívia Souza
Medrado, Alena Ribeiro Alves Peixoto
Andrade, Zilton de Araújo
Reis, Sílvia Regina A.
Pugliese, Lívia Souza
Medrado, Alena Ribeiro Alves Peixoto
dc.subject.por.fl_str_mv Biostimulation
Low-level laser
Skin wounds
topic Biostimulation
Low-level laser
Skin wounds
description Texto completo: acesso restrito. p. 239–244
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2014-01-10T16:21:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/14313
dc.identifier.issn.none.fl_str_mv 0196-8092
identifier_str_mv 0196-8092
url http://repositorio.ufba.br/ri/handle/ri/14313
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1002/lsm.10126
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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