Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects

Detalhes bibliográficos
Autor(a) principal: Jardim, José Roberto
Data de Publicação: 2007
Outros Autores: Camelier, Aquiles Assunção, Corso, Simone Dal, Rodrigues, José Eduardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/14487
Resumo: Texto completo: acesso restrito. p. 1594-1599
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spelling Jardim, José RobertoCamelier, Aquiles AssunçãoCorso, Simone DalRodrigues, José EduardoJardim, José RobertoCamelier, Aquiles AssunçãoCorso, Simone DalRodrigues, José Eduardo2014-01-28T13:25:23Z20070954-6111http://repositorio.ufba.br/ri/handle/ri/14487v. 101, n. 7Texto completo: acesso restrito. p. 1594-1599Objective: To evaluate the effects of the inhaled flunisolide upon the strength and endurance of the respiratory and peripheral muscles of normal subjects. Design: A randomized, double blind and placebo-controlled study. Setting: A university-affiliated teaching hospital. Participants: Thirteen normal volunteers selected from a graduation course. Intervention: Subjects were randomly allocated to receive a placebo or corticosteroid (flunisolide) to be inhaled twice a day for 4 weeks. After 2 weeks of a washout period, subjects who were receiving the placebo, received flunisolide and vise versa for another 4-week period. Measurements and results: Spirometry was used to define the volunteers as being normal in terms of pulmonary function. During the study, subjects performed tests of respiratory muscle function (strength and endurance), measurements of handgrip strength and endurance and anthropometric measurements. Muscle strength was measured each week while muscle endurance was measured every 2 weeks. There was no significant difference in the maximal inspiratory and expiratory pressure and handgrip strength during weeks 1–4 when the subjects used either flunisolide or placebo. However, we observed an increase in the endurance time of the respiratory and handgrip muscles in the 4th week of both flunisolide and placebo use, what may be considered due to a learning effect. Conclusion: Inhalation of flunisolide by normal subjects for 1 month does not cause any acute or clinically perceived effect in the peripheral or respiratory muscles.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-21T16:01:24Z No. of bitstreams: 1 1-s2.0-S0954611106005269-main.pdf: 333601 bytes, checksum: c5233f37c753c6ecbc2f299664b1daed (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-01-28T13:25:23Z (GMT) No. of bitstreams: 1 1-s2.0-S0954611106005269-main.pdf: 333601 bytes, checksum: c5233f37c753c6ecbc2f299664b1daed (MD5)Made available in DSpace on 2014-01-28T13:25:23Z (GMT). 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dc.title.pt_BR.fl_str_mv Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects
dc.title.alternative.pt_BR.fl_str_mv Respiratory Medicine
title Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects
spellingShingle Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects
Jardim, José Roberto
Inhaled corticosteroids
Steroid myopathy
Respiratory muscle strength and endurance
Peripheral muscle
title_short Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects
title_full Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects
title_fullStr Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects
title_full_unstemmed Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects
title_sort Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects
author Jardim, José Roberto
author_facet Jardim, José Roberto
Camelier, Aquiles Assunção
Corso, Simone Dal
Rodrigues, José Eduardo
author_role author
author2 Camelier, Aquiles Assunção
Corso, Simone Dal
Rodrigues, José Eduardo
author2_role author
author
author
dc.contributor.author.fl_str_mv Jardim, José Roberto
Camelier, Aquiles Assunção
Corso, Simone Dal
Rodrigues, José Eduardo
Jardim, José Roberto
Camelier, Aquiles Assunção
Corso, Simone Dal
Rodrigues, José Eduardo
dc.subject.por.fl_str_mv Inhaled corticosteroids
Steroid myopathy
Respiratory muscle strength and endurance
Peripheral muscle
topic Inhaled corticosteroids
Steroid myopathy
Respiratory muscle strength and endurance
Peripheral muscle
description Texto completo: acesso restrito. p. 1594-1599
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-01-28T13:25:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/14487
dc.identifier.issn.none.fl_str_mv 0954-6111
dc.identifier.number.pt_BR.fl_str_mv v. 101, n. 7
identifier_str_mv 0954-6111
v. 101, n. 7
url http://repositorio.ufba.br/ri/handle/ri/14487
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.rmed.2006.10.017
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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