Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/2060 |
Resumo: | p.762-765 |
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Blanton, Ronald EdwardSilva, Luciano K.Morato, Vanessa G.Parrado, Antonio R.Dias, Juarez PereiraMelo, Paulo Roberto Santana deReis, Eliana A. G.Goddard, Katrina A. B.Nunes, Márcio Roberto TeixeiraRodrigues, Sueli G.Vasconcelos, Pedro F. C.Castro, Jesuina M.Reis, Mitermayer Galvão dosBarreto, Mauricio LimaTeixeira, Maria da Glória Lima CruzBlanton, Ronald EdwardSilva, Luciano K.Morato, Vanessa G.Parrado, Antonio R.Dias, Juarez PereiraMelo, Paulo Roberto Santana deReis, Eliana A. G.Goddard, Katrina A. B.Nunes, Márcio Roberto TeixeiraRodrigues, Sueli G.Vasconcelos, Pedro F. C.Castro, Jesuina M.Reis, Mitermayer Galvão dosBarreto, Mauricio LimaTeixeira, Maria da Glória Lima Cruz2011-08-05T01:08:01Z2011-08-05T01:08:01Z2008-02-131018-4813/08http://www.repositorio.ufba.br/ri/handle/ri/2060v. 16p.762-765To test whether African ancestry is protective for severe dengue, we genotyped 49 hospitalized cases of dengue hemorrhagic fever(DHF)as well as 293 neighborhood cases of dengue fevre and 294 asymptomatic controls in Salvador, Bahia, Brazil.Ancestry-informative markers and 282 unlinked SNPs not associated with the clinical presentation of dengue were used to estimate ancestry. After controlling for income,both self-defined Afro-Brazilian ethnicity and African ancestry were protective for DHF (P=0.02, OR=0.28 and P=0.02,OR=0.13,respectively).Income or an index of income indicators, however,was also independently associated with the diagnosis of DHF.Submitted by Rigaud Andréa (andrearigaud16@yahoo.com.br) on 2011-08-05T01:08:01Z No. of bitstreams: 1 per%20int2008.4[1].pdf: 115239 bytes, checksum: 910b1e8af0e8f506e9776e1c78ae926b (MD5)Made available in DSpace on 2011-08-05T01:08:01Z (GMT). No. of bitstreams: 1 per%20int2008.4[1].pdf: 115239 bytes, checksum: 910b1e8af0e8f506e9776e1c78ae926b (MD5) Previous issue date: 2008-02-13ethnicityracepopulation structuresocioeconomic statusDENV3Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed populationEuropean Journal of Human Geneticsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINALper%20int2008.4[1].pdfper%20int2008.4[1].pdfapplication/pdf115239https://repositorio.ufba.br/bitstream/ri/2060/1/per%2520int2008.4%5b1%5d.pdf910b1e8af0e8f506e9776e1c78ae926bMD51LICENSElicense.txtlicense.txttext/plain1906https://repositorio.ufba.br/bitstream/ri/2060/2/license.txt4be0ee38b9d32b8a2f24a1b9348d947dMD52TEXTper%20int2008.4[1].pdf.txtper%20int2008.4[1].pdf.txtExtracted texttext/plain15543https://repositorio.ufba.br/bitstream/ri/2060/3/per%2520int2008.4%5b1%5d.pdf.txt191f05d987b3de7d6b9c818e8203e8c8MD53ri/20602022-07-05 14:03:43.313oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:43Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population |
dc.title.alternative.pt_BR.fl_str_mv |
European Journal of Human Genetics |
title |
Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population |
spellingShingle |
Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population Blanton, Ronald Edward ethnicity race population structure socioeconomic status DENV3 |
title_short |
Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population |
title_full |
Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population |
title_fullStr |
Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population |
title_full_unstemmed |
Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population |
title_sort |
Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population |
author |
Blanton, Ronald Edward |
author_facet |
Blanton, Ronald Edward Silva, Luciano K. Morato, Vanessa G. Parrado, Antonio R. Dias, Juarez Pereira Melo, Paulo Roberto Santana de Reis, Eliana A. G. Goddard, Katrina A. B. Nunes, Márcio Roberto Teixeira Rodrigues, Sueli G. Vasconcelos, Pedro F. C. Castro, Jesuina M. Reis, Mitermayer Galvão dos Barreto, Mauricio Lima Teixeira, Maria da Glória Lima Cruz |
author_role |
author |
author2 |
Silva, Luciano K. Morato, Vanessa G. Parrado, Antonio R. Dias, Juarez Pereira Melo, Paulo Roberto Santana de Reis, Eliana A. G. Goddard, Katrina A. B. Nunes, Márcio Roberto Teixeira Rodrigues, Sueli G. Vasconcelos, Pedro F. C. Castro, Jesuina M. Reis, Mitermayer Galvão dos Barreto, Mauricio Lima Teixeira, Maria da Glória Lima Cruz |
author2_role |
author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Blanton, Ronald Edward Silva, Luciano K. Morato, Vanessa G. Parrado, Antonio R. Dias, Juarez Pereira Melo, Paulo Roberto Santana de Reis, Eliana A. G. Goddard, Katrina A. B. Nunes, Márcio Roberto Teixeira Rodrigues, Sueli G. Vasconcelos, Pedro F. C. Castro, Jesuina M. Reis, Mitermayer Galvão dos Barreto, Mauricio Lima Teixeira, Maria da Glória Lima Cruz Blanton, Ronald Edward Silva, Luciano K. Morato, Vanessa G. Parrado, Antonio R. Dias, Juarez Pereira Melo, Paulo Roberto Santana de Reis, Eliana A. G. Goddard, Katrina A. B. Nunes, Márcio Roberto Teixeira Rodrigues, Sueli G. Vasconcelos, Pedro F. C. Castro, Jesuina M. Reis, Mitermayer Galvão dos Barreto, Mauricio Lima Teixeira, Maria da Glória Lima Cruz |
dc.subject.por.fl_str_mv |
ethnicity race population structure socioeconomic status DENV3 |
topic |
ethnicity race population structure socioeconomic status DENV3 |
description |
p.762-765 |
publishDate |
2008 |
dc.date.issued.fl_str_mv |
2008-02-13 |
dc.date.accessioned.fl_str_mv |
2011-08-05T01:08:01Z |
dc.date.available.fl_str_mv |
2011-08-05T01:08:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/2060 |
dc.identifier.issn.none.fl_str_mv |
1018-4813/08 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 16 |
identifier_str_mv |
1018-4813/08 v. 16 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/2060 |
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eng |
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openAccess |
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