Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease

Detalhes bibliográficos
Autor(a) principal: Valença, Guilherme T.
Data de Publicação: 2013
Outros Autores: Glass, Philip G., Negreiros, Nadja N., Duarte, Meirelayne Borges, Ventura, Lais M. G. B., Mueller, Mila, Oliveira Filho, Jamary
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15141
Resumo: Texto completo: acesso restrito. p. 698–700
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spelling Valença, Guilherme T.Glass, Philip G.Negreiros, Nadja N.Duarte, Meirelayne BorgesVentura, Lais M. G. B.Mueller, MilaOliveira Filho, JamaryValença, Guilherme T.Glass, Philip G.Negreiros, Nadja N.Duarte, Meirelayne BorgesVentura, Lais M. G. B.Mueller, MilaOliveira Filho, Jamary2014-07-07T20:36:38Z20131353-8020http://repositorio.ufba.br/ri/handle/ri/15141v. 19, n. 7Texto completo: acesso restrito. p. 698–700Background: Previous studies have described the association between dopamine replacement therapy in Parkinson's disease and impulse control disorders. Methods: A case–control study was performed to establish the prevalence of four of these behaviors in Brazilian patients with Parkinson's disease on stable dopamine replacement therapy and the possible associated risk factors. We investigated 152 patients and 212 healthy controls for pathological gambling, compulsive sexual behavior and compulsive buying and eating. Results: Overall, patients had more impulsive control disorders than controls (18.4% vs. 4.2%, P < 0.001). Impulse control disorders were more common in younger patients (P = 0.008) and in those taking dopamine agonist (P < 0.001) and levodopa (P = 0.02). Higher Unified Parkinson's Disease Rating Scale motor score (P = 0.03) and past smoking (P = 0.02) were also associated in the univariate analysis. Variables independently associated with impulse control disorders were history of smoking (odds ratio = 1.059 for each year of smoking, P = 0.010) and current use of pramipexole (odds ratio = 2.551 for each increase in 1 mg, P < 0.001). Conclusions: Dopaminergic stimulation and previous exposure to smoking are independently associated with impulse control disorders in a dose-dependent manner.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-06-03T11:47:50Z No. of bitstreams: 1 1-s2.0-S135380201300120X-main.pdf: 167964 bytes, checksum: d361c4cefa6e8c1dedf4e96f007b83e6 (MD5)Approved for entry into archive by Patricia Barroso (pbarroso@ufba.br) on 2014-07-07T20:36:38Z (GMT) No. of bitstreams: 1 1-s2.0-S135380201300120X-main.pdf: 167964 bytes, checksum: d361c4cefa6e8c1dedf4e96f007b83e6 (MD5)Made available in DSpace on 2014-07-07T20:36:38Z (GMT). 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dc.title.pt_BR.fl_str_mv Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
dc.title.alternative.pt_BR.fl_str_mv Parkinsonism and Related Disorders
title Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
spellingShingle Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
Valença, Guilherme T.
Parkinson's disease
Impulse control disorders
Dopamine agonist
Smoking
title_short Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
title_full Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
title_fullStr Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
title_full_unstemmed Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
title_sort Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
author Valença, Guilherme T.
author_facet Valença, Guilherme T.
Glass, Philip G.
Negreiros, Nadja N.
Duarte, Meirelayne Borges
Ventura, Lais M. G. B.
Mueller, Mila
Oliveira Filho, Jamary
author_role author
author2 Glass, Philip G.
Negreiros, Nadja N.
Duarte, Meirelayne Borges
Ventura, Lais M. G. B.
Mueller, Mila
Oliveira Filho, Jamary
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Valença, Guilherme T.
Glass, Philip G.
Negreiros, Nadja N.
Duarte, Meirelayne Borges
Ventura, Lais M. G. B.
Mueller, Mila
Oliveira Filho, Jamary
Valença, Guilherme T.
Glass, Philip G.
Negreiros, Nadja N.
Duarte, Meirelayne Borges
Ventura, Lais M. G. B.
Mueller, Mila
Oliveira Filho, Jamary
dc.subject.por.fl_str_mv Parkinson's disease
Impulse control disorders
Dopamine agonist
Smoking
topic Parkinson's disease
Impulse control disorders
Dopamine agonist
Smoking
description Texto completo: acesso restrito. p. 698–700
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-07-07T20:36:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15141
dc.identifier.issn.none.fl_str_mv 1353-8020
dc.identifier.number.pt_BR.fl_str_mv v. 19, n. 7
identifier_str_mv 1353-8020
v. 19, n. 7
url http://repositorio.ufba.br/ri/handle/ri/15141
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.parkreldis.2013.03.004
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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