Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/15141 |
Resumo: | Texto completo: acesso restrito. p. 698–700 |
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Valença, Guilherme T.Glass, Philip G.Negreiros, Nadja N.Duarte, Meirelayne BorgesVentura, Lais M. G. B.Mueller, MilaOliveira Filho, JamaryValença, Guilherme T.Glass, Philip G.Negreiros, Nadja N.Duarte, Meirelayne BorgesVentura, Lais M. G. B.Mueller, MilaOliveira Filho, Jamary2014-07-07T20:36:38Z20131353-8020http://repositorio.ufba.br/ri/handle/ri/15141v. 19, n. 7Texto completo: acesso restrito. p. 698–700Background: Previous studies have described the association between dopamine replacement therapy in Parkinson's disease and impulse control disorders. Methods: A case–control study was performed to establish the prevalence of four of these behaviors in Brazilian patients with Parkinson's disease on stable dopamine replacement therapy and the possible associated risk factors. We investigated 152 patients and 212 healthy controls for pathological gambling, compulsive sexual behavior and compulsive buying and eating. Results: Overall, patients had more impulsive control disorders than controls (18.4% vs. 4.2%, P < 0.001). Impulse control disorders were more common in younger patients (P = 0.008) and in those taking dopamine agonist (P < 0.001) and levodopa (P = 0.02). Higher Unified Parkinson's Disease Rating Scale motor score (P = 0.03) and past smoking (P = 0.02) were also associated in the univariate analysis. Variables independently associated with impulse control disorders were history of smoking (odds ratio = 1.059 for each year of smoking, P = 0.010) and current use of pramipexole (odds ratio = 2.551 for each increase in 1 mg, P < 0.001). Conclusions: Dopaminergic stimulation and previous exposure to smoking are independently associated with impulse control disorders in a dose-dependent manner.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-06-03T11:47:50Z No. of bitstreams: 1 1-s2.0-S135380201300120X-main.pdf: 167964 bytes, checksum: d361c4cefa6e8c1dedf4e96f007b83e6 (MD5)Approved for entry into archive by Patricia Barroso (pbarroso@ufba.br) on 2014-07-07T20:36:38Z (GMT) No. of bitstreams: 1 1-s2.0-S135380201300120X-main.pdf: 167964 bytes, checksum: d361c4cefa6e8c1dedf4e96f007b83e6 (MD5)Made available in DSpace on 2014-07-07T20:36:38Z (GMT). No. of bitstreams: 1 1-s2.0-S135380201300120X-main.pdf: 167964 bytes, checksum: d361c4cefa6e8c1dedf4e96f007b83e6 (MD5) Previous issue date: 2013http://dx.doi.org/10.1016/j.parkreldis.2013.03.004reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAParkinson's diseaseImpulse control disordersDopamine agonistSmokingPast smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's diseaseParkinsonism and Related Disordersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL1-s2.0-S135380201300120X-main.pdf1-s2.0-S135380201300120X-main.pdfapplication/pdf167964https://repositorio.ufba.br/bitstream/ri/15141/1/1-s2.0-S135380201300120X-main.pdfd361c4cefa6e8c1dedf4e96f007b83e6MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15141/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXT1-s2.0-S135380201300120X-main.pdf.txt1-s2.0-S135380201300120X-main.pdf.txtExtracted texttext/plain17490https://repositorio.ufba.br/bitstream/ri/15141/3/1-s2.0-S135380201300120X-main.pdf.txt9ada36715a072b0c0533c9da8d09a837MD53ri/151412022-07-05 14:03:31.027oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:31Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease |
dc.title.alternative.pt_BR.fl_str_mv |
Parkinsonism and Related Disorders |
title |
Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease |
spellingShingle |
Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease Valença, Guilherme T. Parkinson's disease Impulse control disorders Dopamine agonist Smoking |
title_short |
Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease |
title_full |
Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease |
title_fullStr |
Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease |
title_full_unstemmed |
Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease |
title_sort |
Past smoking and current dopamine agonist use show an independent and dose-dependent association with impulse control disorders in Parkinson's disease |
author |
Valença, Guilherme T. |
author_facet |
Valença, Guilherme T. Glass, Philip G. Negreiros, Nadja N. Duarte, Meirelayne Borges Ventura, Lais M. G. B. Mueller, Mila Oliveira Filho, Jamary |
author_role |
author |
author2 |
Glass, Philip G. Negreiros, Nadja N. Duarte, Meirelayne Borges Ventura, Lais M. G. B. Mueller, Mila Oliveira Filho, Jamary |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Valença, Guilherme T. Glass, Philip G. Negreiros, Nadja N. Duarte, Meirelayne Borges Ventura, Lais M. G. B. Mueller, Mila Oliveira Filho, Jamary Valença, Guilherme T. Glass, Philip G. Negreiros, Nadja N. Duarte, Meirelayne Borges Ventura, Lais M. G. B. Mueller, Mila Oliveira Filho, Jamary |
dc.subject.por.fl_str_mv |
Parkinson's disease Impulse control disorders Dopamine agonist Smoking |
topic |
Parkinson's disease Impulse control disorders Dopamine agonist Smoking |
description |
Texto completo: acesso restrito. p. 698–700 |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
dc.date.accessioned.fl_str_mv |
2014-07-07T20:36:38Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufba.br/ri/handle/ri/15141 |
dc.identifier.issn.none.fl_str_mv |
1353-8020 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 19, n. 7 |
identifier_str_mv |
1353-8020 v. 19, n. 7 |
url |
http://repositorio.ufba.br/ri/handle/ri/15141 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
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http://dx.doi.org/10.1016/j.parkreldis.2013.03.004 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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