Altered cytokeratin expression in actinic cheilitis

Detalhes bibliográficos
Autor(a) principal: Santos, Jean Nunes dos
Data de Publicação: 2003
Outros Autores: Sousa, Suzana Orsini Machado de, Nunes, Fabio Daumas, Sotto, Miriam N., Araújo, Vera Cavalcanti de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/14638
Resumo: Texto completo: acesso restrito. p. 237–241
id UFBA-2_466fc32dda8d9229f9eb224eb064986b
oai_identifier_str oai:repositorio.ufba.br:ri/14638
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Santos, Jean Nunes dosSousa, Suzana Orsini Machado deNunes, Fabio DaumasSotto, Miriam N.Araújo, Vera Cavalcanti deSantos, Jean Nunes dosSousa, Suzana Orsini Machado deNunes, Fabio DaumasSotto, Miriam N.Araújo, Vera Cavalcanti de2014-02-19T18:23:45Z20030303-6987http://repositorio.ufba.br/ri/handle/ri/14638v. 30, n. 4Texto completo: acesso restrito. p. 237–241Background:  Actinic cheilitis (AC) is a widely recognized precancerous lesion of the lip. Varying degrees of epithelial dysplasia may be present. However, no studies have correlated epithelial changes with cytokeratin expression that might reflect the disordered maturation that is probably occurring. Methods:  Thirty-four cases diagnosed as AC were classified according to dysplasia degree, and submitted to immunohistochemical staining for the detection of cytokeratins (CKs) 7, 8, 13, 14, 16 and 19. Normal mucosa adjacent to the lesions was also evaluated. Results:  The results obtained showed that CK10 immunostained only superficial keratinized epithelial layers in 11 cases, and also intermediate spinous layers in 18 cases. Cytokeratin 14 was expressed in all epithelial layers of 31 cases, in two cases its expression was in the basal and intermediate layers, and one case was negative. Cytokeratin 13 immunostained 26 cases and was negative in eight cases. In these eight cases, CK13 was apparently replaced by CK16. Cytokeratin 16, besides these eight cases, was also expressed in the spinous intermediate layers of a further eight cases. The remaining CKs tested were all negative. No relation between the degree of dysplasia and the CK expression was noted. Conclusions:  Cytokeratin expression in AC is different from that of normal oral mucosa, and is not related to the degree of dysplasia.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-01-13T11:02:09Z No. of bitstreams: 1 Jean N. dos Santos.pdf: 2710760 bytes, checksum: a33e31798ec8d78ee7a1185051c1b37a (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-02-19T18:23:45Z (GMT) No. of bitstreams: 1 Jean N. dos Santos.pdf: 2710760 bytes, checksum: a33e31798ec8d78ee7a1185051c1b37a (MD5)Made available in DSpace on 2014-02-19T18:23:45Z (GMT). No. of bitstreams: 1 Jean N. dos Santos.pdf: 2710760 bytes, checksum: a33e31798ec8d78ee7a1185051c1b37a (MD5) Previous issue date: 2003http://dx.doi.org/ 10.1046/j.0303-6987.2002.028.xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAActinic cheilitisCytokeratinAltered cytokeratin expression in actinic cheilitisJournal of Cutaneous Pathologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALJean N. dos Santos.pdfJean N. dos Santos.pdfapplication/pdf2710760https://repositorio.ufba.br/bitstream/ri/14638/1/Jean%20N.%20dos%20Santos.pdfa33e31798ec8d78ee7a1185051c1b37aMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/14638/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTJean N. dos Santos.pdf.txtJean N. dos Santos.pdf.txtExtracted texttext/plain19500https://repositorio.ufba.br/bitstream/ri/14638/3/Jean%20N.%20dos%20Santos.pdf.txt97949c62bb346004ebaf3a6ef9c666abMD53ri/146382022-07-05 14:03:03.865oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestrepositorio@ufba.bropendoar:19322022-07-05T17:03:03Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Altered cytokeratin expression in actinic cheilitis
dc.title.alternative.pt_BR.fl_str_mv Journal of Cutaneous Pathology
title Altered cytokeratin expression in actinic cheilitis
spellingShingle Altered cytokeratin expression in actinic cheilitis
Santos, Jean Nunes dos
Actinic cheilitis
Cytokeratin
title_short Altered cytokeratin expression in actinic cheilitis
title_full Altered cytokeratin expression in actinic cheilitis
title_fullStr Altered cytokeratin expression in actinic cheilitis
title_full_unstemmed Altered cytokeratin expression in actinic cheilitis
title_sort Altered cytokeratin expression in actinic cheilitis
author Santos, Jean Nunes dos
author_facet Santos, Jean Nunes dos
Sousa, Suzana Orsini Machado de
Nunes, Fabio Daumas
Sotto, Miriam N.
Araújo, Vera Cavalcanti de
author_role author
author2 Sousa, Suzana Orsini Machado de
Nunes, Fabio Daumas
Sotto, Miriam N.
Araújo, Vera Cavalcanti de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos, Jean Nunes dos
Sousa, Suzana Orsini Machado de
Nunes, Fabio Daumas
Sotto, Miriam N.
Araújo, Vera Cavalcanti de
Santos, Jean Nunes dos
Sousa, Suzana Orsini Machado de
Nunes, Fabio Daumas
Sotto, Miriam N.
Araújo, Vera Cavalcanti de
dc.subject.por.fl_str_mv Actinic cheilitis
Cytokeratin
topic Actinic cheilitis
Cytokeratin
description Texto completo: acesso restrito. p. 237–241
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2014-02-19T18:23:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/14638
dc.identifier.issn.none.fl_str_mv 0303-6987
dc.identifier.number.pt_BR.fl_str_mv v. 30, n. 4
identifier_str_mv 0303-6987
v. 30, n. 4
url http://repositorio.ufba.br/ri/handle/ri/14638
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1046/j.0303-6987.2002.028.x
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/14638/1/Jean%20N.%20dos%20Santos.pdf
https://repositorio.ufba.br/bitstream/ri/14638/2/license.txt
https://repositorio.ufba.br/bitstream/ri/14638/3/Jean%20N.%20dos%20Santos.pdf.txt
bitstream.checksum.fl_str_mv a33e31798ec8d78ee7a1185051c1b37a
ff6eaa8b858ea317fded99f125f5fcd0
97949c62bb346004ebaf3a6ef9c666ab
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv repositorio@ufba.br
_version_ 1828148886331457536

Registros relacionados