Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery

Detalhes bibliográficos
Autor(a) principal: Cueva, Clotario Neptali Carrasco
Data de Publicação: 2013
Outros Autores: Rocha, Maiara dos Santos, Mendes, Carlos Maurício Cardeal, Freitas, Luiz Antonio Rodrigues de, Baucia, José Augusto, Badaró, Roberto José da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/17778
Resumo: p. 270-280
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spelling Cueva, Clotario Neptali CarrascoRocha, Maiara dos SantosMendes, Carlos Maurício CardealFreitas, Luiz Antonio Rodrigues deBaucia, José AugustoBadaró, Roberto José da SilvaCueva, Clotario Neptali CarrascoRocha, Maiara dos SantosMendes, Carlos Maurício CardealFreitas, Luiz Antonio Rodrigues deBaucia, José AugustoBadaró, Roberto José da Silva2015-05-28T14:46:01Z2015-05-28T14:46:01Z20130102-7638http://repositorio.ufba.br/ri/handle/ri/17778v. 28, n. 2p. 270-280INTRODUCTION: Beating heart surgery on normothermic bypass simulates physiologic cardiac status. OBJECTIVES: This study compared clinical and transmission electron microscopic aspects of myocardial protection during mitral valve replacement using warm retrograde perfusion in empty beating versus arrested heart with cold blood anterograde cardioplegia. METHODS: Randomized study to evaluate myocardial cellular ischemia-reperfusion of both techniques to replace the mitral valve. Thirty-four patients were randomly assigned into group A (beating heart) and group B (arrested heart). The following parameters were assessed: echocardiography, blood chemistry, hemoglobin, lactate. During the surgical procedure a total of 102 myocardial biopsies were performed for ultrastructural analysis from anterior left ventricular wall: before cardiopulmonary bypass, before aortic desclamping and 10 minutes after reperfusion. RESULTS: Elevation of lactate at 3 hours during the procedure was higher in group A, but similar at the end of surgery (P=0.06). Cardioversion was necessary in 5/17 (A) vs. 13/17 (B) P=0.07. Median intraoperative systemic temperature was significantly lower in the group B compared to A (32ºC vs. 36ºC), P<0.001. There was no significant difference of the ultramicroscopic aspects of the heart biopsies before, during and after surgery in both groups. Cellular and mitochondrial transient abnormalities such as mitochondrial swelling, glycogen loss and cytosol swelling were detected independently of the moment of the biopsies. CONCLUSION: Myocardial protection and ultrastructural abnormalities were similar for both types of mitral valve replacement beating or arrested heart techniques.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-12-03T12:27:56Z No. of bitstreams: 1 Clotario Neptali Carrasco Cueva.pdf: 1997890 bytes, checksum: c985ead0e2654504f2890d4a3ae15d35 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-05-28T14:46:01Z (GMT) No. of bitstreams: 1 Clotario Neptali Carrasco Cueva.pdf: 1997890 bytes, checksum: c985ead0e2654504f2890d4a3ae15d35 (MD5)Made available in DSpace on 2015-05-28T14:46:01Z (GMT). No. of bitstreams: 1 Clotario Neptali Carrasco Cueva.pdf: 1997890 bytes, checksum: c985ead0e2654504f2890d4a3ae15d35 (MD5) Previous issue date: 2013http://dx.doi.org/10.5935/1678-9741.20130038reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHeart ArrestInducedMyocardiumMitral ValveSurgeryClinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgeryRevista Brasileira de Cirurgia Cardiovascularinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessengORIGINALClotario Neptali Carrasco Cueva.pdfClotario Neptali Carrasco Cueva.pdfapplication/pdf1997890https://repositorio.ufba.br/bitstream/ri/17778/1/Clotario%20Neptali%20Carrasco%20Cueva.pdfc985ead0e2654504f2890d4a3ae15d35MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/17778/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTClotario Neptali Carrasco Cueva.pdf.txtClotario Neptali Carrasco Cueva.pdf.txtExtracted texttext/plain41409https://repositorio.ufba.br/bitstream/ri/17778/3/Clotario%20Neptali%20Carrasco%20Cueva.pdf.txt26e6e931cd7df5099fee7ea2690ac89aMD53ri/177782022-08-08 13:17:49.748oai:repositorio.ufba.br:ri/17778VGVybW8gZGUgTGljZW7vv71hLCBu77+9byBleGNsdXNpdm8sIHBhcmEgbyBkZXDvv71zaXRvIG5vIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBLgoKIFBlbG8gcHJvY2Vzc28gZGUgc3VibWlzc++/vW8gZGUgZG9jdW1lbnRvcywgbyBhdXRvciBvdSBzZXUgcmVwcmVzZW50YW50ZSBsZWdhbCwgYW8gYWNlaXRhciAKZXNzZSB0ZXJtbyBkZSBsaWNlbu+/vWEsIGNvbmNlZGUgYW8gUmVwb3NpdO+/vXJpbyBJbnN0aXR1Y2lvbmFsIGRhIFVuaXZlcnNpZGFkZSBGZWRlcmFsIGRhIEJhaGlhIApvIGRpcmVpdG8gZGUgbWFudGVyIHVtYSBj77+9cGlhIGVtIHNldSByZXBvc2l077+9cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCBkZSBwcmVzZXJ2Ye+/ve+/vW8uIApFc3NlcyB0ZXJtb3MsIG7vv71vIGV4Y2x1c2l2b3MsIG1hbnTvv71tIG9zIGRpcmVpdG9zIGRlIGF1dG9yL2NvcHlyaWdodCwgbWFzIGVudGVuZGUgbyBkb2N1bWVudG8gCmNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsIGRlc3NhIFVuaXZlcnNpZGFkZS4KCiBQYXJhIG9zIGRvY3VtZW50b3MgcHVibGljYWRvcyBjb20gcmVwYXNzZSBkZSBkaXJlaXRvcyBkZSBkaXN0cmlidWnvv73vv71vLCBlc3NlIHRlcm1vIGRlIGxpY2Vu77+9YSAKZW50ZW5kZSBxdWU6CgogTWFudGVuZG8gb3MgZGlyZWl0b3MgYXV0b3JhaXMsIHJlcGFzc2Fkb3MgYSB0ZXJjZWlyb3MsIGVtIGNhc28gZGUgcHVibGljYe+/ve+/vWVzLCBvIHJlcG9zaXTvv71yaW8KcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIGludGVncmFsLCBtYXMgbGliZXJhIGFzIGluZm9ybWHvv73vv71lcyBzb2JyZSBvIGRvY3VtZW50bwooTWV0YWRhZG9zIGVzY3JpdGl2b3MpLgoKIERlc3RhIGZvcm1hLCBhdGVuZGVuZG8gYW9zIGFuc2Vpb3MgZGVzc2EgdW5pdmVyc2lkYWRlIGVtIG1hbnRlciBzdWEgcHJvZHXvv73vv71vIGNpZW5077+9ZmljYSBjb20gCmFzIHJlc3Ryae+/ve+/vWVzIGltcG9zdGFzIHBlbG9zIGVkaXRvcmVzIGRlIHBlcmnvv71kaWNvcy4KCiBQYXJhIGFzIHB1YmxpY2Hvv73vv71lcyBzZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbO+/vXRpY2EgZGUgQWNlc3NvIEFiZXJ0bywgb3MgZGVw77+9c2l0b3MgCmNvbXB1bHPvv71yaW9zIG5lc3NlIHJlcG9zaXTvv71yaW8gbWFudO+/vW0gb3MgZGlyZWl0b3MgYXV0b3JhaXMsIG1hcyBtYW5077+9bSBhY2Vzc28gaXJyZXN0cml0byAKYW8gbWV0YWRhZG9zIGUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0Ye+/ve+/vW8gZGVzc2UgdGVybW8gbu+/vW8gbmVjZXNzaXRhIGRlIGNvbnNlbnRpbWVudG8KIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgZXN0YXJlbSBlbSBpbmljaWF0aXZhcyBkZSBhY2Vzc28gYWJlcnRvLgo=Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:49Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery
dc.title.alternative.pt_BR.fl_str_mv Revista Brasileira de Cirurgia Cardiovascular
title Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery
spellingShingle Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery
Cueva, Clotario Neptali Carrasco
Heart Arrest
Induced
Myocardium
Mitral Valve
Surgery
title_short Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery
title_full Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery
title_fullStr Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery
title_full_unstemmed Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery
title_sort Clinical and ultramicroscopic myocardial randomized study of beating versus arrested heart for mitral surgery
author Cueva, Clotario Neptali Carrasco
author_facet Cueva, Clotario Neptali Carrasco
Rocha, Maiara dos Santos
Mendes, Carlos Maurício Cardeal
Freitas, Luiz Antonio Rodrigues de
Baucia, José Augusto
Badaró, Roberto José da Silva
author_role author
author2 Rocha, Maiara dos Santos
Mendes, Carlos Maurício Cardeal
Freitas, Luiz Antonio Rodrigues de
Baucia, José Augusto
Badaró, Roberto José da Silva
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cueva, Clotario Neptali Carrasco
Rocha, Maiara dos Santos
Mendes, Carlos Maurício Cardeal
Freitas, Luiz Antonio Rodrigues de
Baucia, José Augusto
Badaró, Roberto José da Silva
Cueva, Clotario Neptali Carrasco
Rocha, Maiara dos Santos
Mendes, Carlos Maurício Cardeal
Freitas, Luiz Antonio Rodrigues de
Baucia, José Augusto
Badaró, Roberto José da Silva
dc.subject.por.fl_str_mv Heart Arrest
Induced
Myocardium
Mitral Valve
Surgery
topic Heart Arrest
Induced
Myocardium
Mitral Valve
Surgery
description p. 270-280
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2015-05-28T14:46:01Z
dc.date.available.fl_str_mv 2015-05-28T14:46:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/17778
dc.identifier.issn.none.fl_str_mv 0102-7638
dc.identifier.number.pt_BR.fl_str_mv v. 28, n. 2
identifier_str_mv 0102-7638
v. 28, n. 2
url http://repositorio.ufba.br/ri/handle/ri/17778
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.5935/1678-9741.20130038
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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institution UFBA
reponame_str Repositório Institucional da UFBA
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