Clinical manifestations in individuals with recent diagnosis of HTLV type I infection

Detalhes bibliográficos
Autor(a) principal: Poetker, Shelene K. W.
Data de Publicação: 2011
Outros Autores: Porto, Maria Aurélia da Fonseca, Giozza, Silvana P., Muniz, André Luís Nunes, Caskey, Marina F., Carvalho Filho, Edgar Marcelino de, Glesby, Marshall J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16603
Resumo: Texto completo: acesso restrito. p. 54–58
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spelling Poetker, Shelene K. W.Porto, Maria Aurélia da FonsecaGiozza, Silvana P.Muniz, André Luís NunesCaskey, Marina F.Carvalho Filho, Edgar Marcelino deGlesby, Marshall J.Poetker, Shelene K. W.Porto, Maria Aurélia da FonsecaGiozza, Silvana P.Muniz, André Luís NunesCaskey, Marina F.Carvalho Filho, Edgar Marcelino deGlesby, Marshall J.2014-11-14T13:15:34Z20111386-6532http://repositorio.ufba.br/ri/handle/ri/16603v. 51, n. 1Texto completo: acesso restrito. p. 54–58Background: Human T-lymphotropic virus type 1 (HTLV-1) is known to cause HTLV-associated myelopathy (HAM)/tropical spastic paraparesis and adult T cell leukemia. A growing body of evidence links HTLV-1 infection with an increasing spectrum of disease, including uveitis, periodontal disease, arthropathy, sicca syndrome, and neurologic deficits. Objectives: Despite recent findings, the natural history of HTLV-1 infection remains poorly defined. This study was designed to better characterize initial clinical and neurological findings in individuals diagnosed with HTLV-1 infection. Study design: We conducted a cross-sectional study of 71 individuals recently diagnosed with HTLV-1 and 71 uninfected age- and sex-matched blood donors in Salvador, Brazil. Subjects were administered a standardized questionnaire and underwent physical exam. Results: HTLV-1 infected subjects were significantly more likely than controls to report complaints of hand and foot numbness (OR = 5.3; 95% CI: 1.8–15.3; p = 0.002 and OR = 4.0; 95% CI: 1.3–12; p = 0.013 respectively), difficulty running (OR = 4.0; 95% CI: 1.1–14.2; p = 0.032), nocturia (OR = 5.0; 95% CI: 1.1–22.8; p = 0.038), arthralgia (OR = 3.3; 95% CI: 1.4–7.7; p = 0.006), and photophobia (OR = 3.3; 95% CI: 1.4–7.7; p = 0.006). Conclusions: Neurologic, ocular and rheumatologic complaints may be the first manifestations of HTLV-1 infection. Therefore, all patients presenting with initial diagnosis should be rigorously screened for these symptoms.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-04-01T13:07:10Z No. of bitstreams: 1 Aurelia F. Portoa.pdf: 149639 bytes, checksum: af9a8b529979ef4f972b27db572d6d04 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-11-14T13:15:34Z (GMT) No. of bitstreams: 1 Aurelia F. Portoa.pdf: 149639 bytes, checksum: af9a8b529979ef4f972b27db572d6d04 (MD5)Made available in DSpace on 2014-11-14T13:15:34Z (GMT). No. of bitstreams: 1 Aurelia F. Portoa.pdf: 149639 bytes, checksum: af9a8b529979ef4f972b27db572d6d04 (MD5) Previous issue date: 2011http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.jcv.2011.02.004reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHTLV-1Neurologic manifestationsClinical manifestationsNeuropathyNatural historyClinical manifestations in individuals with recent diagnosis of HTLV type I infectionJournal of Clinical Virologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALAurelia F. Portoa.pdfAurelia F. Portoa.pdfapplication/pdf149639https://repositorio.ufba.br/bitstream/ri/16603/1/Aurelia%20F.%20Portoa.pdfaf9a8b529979ef4f972b27db572d6d04MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16603/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXTAurelia F. Portoa.pdf.txtAurelia F. 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dc.title.pt_BR.fl_str_mv Clinical manifestations in individuals with recent diagnosis of HTLV type I infection
dc.title.alternative.pt_BR.fl_str_mv Journal of Clinical Virology
title Clinical manifestations in individuals with recent diagnosis of HTLV type I infection
spellingShingle Clinical manifestations in individuals with recent diagnosis of HTLV type I infection
Poetker, Shelene K. W.
HTLV-1
Neurologic manifestations
Clinical manifestations
Neuropathy
Natural history
title_short Clinical manifestations in individuals with recent diagnosis of HTLV type I infection
title_full Clinical manifestations in individuals with recent diagnosis of HTLV type I infection
title_fullStr Clinical manifestations in individuals with recent diagnosis of HTLV type I infection
title_full_unstemmed Clinical manifestations in individuals with recent diagnosis of HTLV type I infection
title_sort Clinical manifestations in individuals with recent diagnosis of HTLV type I infection
author Poetker, Shelene K. W.
author_facet Poetker, Shelene K. W.
Porto, Maria Aurélia da Fonseca
Giozza, Silvana P.
Muniz, André Luís Nunes
Caskey, Marina F.
Carvalho Filho, Edgar Marcelino de
Glesby, Marshall J.
author_role author
author2 Porto, Maria Aurélia da Fonseca
Giozza, Silvana P.
Muniz, André Luís Nunes
Caskey, Marina F.
Carvalho Filho, Edgar Marcelino de
Glesby, Marshall J.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Poetker, Shelene K. W.
Porto, Maria Aurélia da Fonseca
Giozza, Silvana P.
Muniz, André Luís Nunes
Caskey, Marina F.
Carvalho Filho, Edgar Marcelino de
Glesby, Marshall J.
Poetker, Shelene K. W.
Porto, Maria Aurélia da Fonseca
Giozza, Silvana P.
Muniz, André Luís Nunes
Caskey, Marina F.
Carvalho Filho, Edgar Marcelino de
Glesby, Marshall J.
dc.subject.por.fl_str_mv HTLV-1
Neurologic manifestations
Clinical manifestations
Neuropathy
Natural history
topic HTLV-1
Neurologic manifestations
Clinical manifestations
Neuropathy
Natural history
description Texto completo: acesso restrito. p. 54–58
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2014-11-14T13:15:34Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16603
dc.identifier.issn.none.fl_str_mv 1386-6532
dc.identifier.number.pt_BR.fl_str_mv v. 51, n. 1
identifier_str_mv 1386-6532
v. 51, n. 1
url http://repositorio.ufba.br/ri/handle/ri/16603
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.jcv.2011.02.004
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