A chemotherapy model for the treatment of cancer with metastasis

Detalhes bibliográficos
Autor(a) principal: Pinho, Suani Tavares Rubim de
Data de Publicação: 2002
Outros Autores: Freedman, H. I., Nani, F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/7442
Resumo: Texto completo: acesso restrito. p. 773-803
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spelling Pinho, Suani Tavares Rubim deFreedman, H. I.Nani, F.Pinho, Suani Tavares Rubim deFreedman, H. I.Nani, F.2012-12-12T11:47:29Z2002-110895-7177http://www.repositorio.ufba.br/ri/handle/ri/7442v. 36, n. 7-8Texto completo: acesso restrito. p. 773-803In this paper, we propose and analyse a mathematical model of cancer treatment by chemotherapy where there is metastasis from a primary to a secondary site by the cancer cells. We view the interactions between normal and cancer cells as being competitive for available resources, and we think of the chemotherapy agent as a predator on both normal and cancer cells. The metastasis may be time delayed. The analysis is carried out both analytically (where possible) and numerically. In particular, we look at the existence and stability of equilibria of our model, which consists of six differential equations. As well, we investigate (numerically) the behavior of solutions for various values of the parameters.Submitted by Suelen Reis (suelen_suzane@hotmail.com) on 2012-12-12T11:47:29Z No. of bitstreams: 1 1-s2.0-S0895717702002273-main.pdf: 3087586 bytes, checksum: ab940c0ba1c57b163cb27c16f0b8a5ee (MD5)Made available in DSpace on 2012-12-12T11:47:29Z (GMT). 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dc.title.pt_BR.fl_str_mv A chemotherapy model for the treatment of cancer with metastasis
dc.title.alternative.pt_BR.fl_str_mv Mathematical and Computer Modelling
title A chemotherapy model for the treatment of cancer with metastasis
spellingShingle A chemotherapy model for the treatment of cancer with metastasis
Pinho, Suani Tavares Rubim de
Competition models
Chemotherapy
Metastasis; Stability
Time delay
title_short A chemotherapy model for the treatment of cancer with metastasis
title_full A chemotherapy model for the treatment of cancer with metastasis
title_fullStr A chemotherapy model for the treatment of cancer with metastasis
title_full_unstemmed A chemotherapy model for the treatment of cancer with metastasis
title_sort A chemotherapy model for the treatment of cancer with metastasis
author Pinho, Suani Tavares Rubim de
author_facet Pinho, Suani Tavares Rubim de
Freedman, H. I.
Nani, F.
author_role author
author2 Freedman, H. I.
Nani, F.
author2_role author
author
dc.contributor.author.fl_str_mv Pinho, Suani Tavares Rubim de
Freedman, H. I.
Nani, F.
Pinho, Suani Tavares Rubim de
Freedman, H. I.
Nani, F.
dc.subject.por.fl_str_mv Competition models
Chemotherapy
Metastasis; Stability
Time delay
topic Competition models
Chemotherapy
Metastasis; Stability
Time delay
description Texto completo: acesso restrito. p. 773-803
publishDate 2002
dc.date.issued.fl_str_mv 2002-11
dc.date.accessioned.fl_str_mv 2012-12-12T11:47:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/7442
dc.identifier.issn.none.fl_str_mv 0895-7177
dc.identifier.number.pt_BR.fl_str_mv v. 36, n. 7-8
identifier_str_mv 0895-7177
v. 36, n. 7-8
url http://www.repositorio.ufba.br/ri/handle/ri/7442
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/S0895-7177(02)00227-3
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
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reponame_str Repositório Institucional da UFBA
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