Hospital readmissions related to drug interactions: a retrospective study in a hospital setting

Detalhes bibliográficos
Autor(a) principal: Moura, Cristiano Soares de
Data de Publicação: 2012
Outros Autores: Tavares, Ludmila Santana, Acurcio, Francisco de Assis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/14907
Resumo: p. 1-7
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spelling Moura, Cristiano Soares deTavares, Ludmila SantanaAcurcio, Francisco de AssisMoura, Cristiano Soares deTavares, Ludmila SantanaAcurcio, Francisco de Assis2014-05-06T13:19:50Z2014-05-06T13:19:50Z20120034-8910,http://repositorio.ufba.br/ri/handle/ri/14907v. 46, n. 6p. 1-7OBJECTIVE: To examine the relationship between potential drug interactions and hospital readmissions. METHODS: Retrospective study with 1,487 adult patients (> 18 years old) admitted to a general hospital in the city of Vitória da Conquista, Northeastern Brazil, from January to December 2007. Data were collected from Hospital Admission Authorization (AIH) forms in the Brazilian National Health System Hospital Database (SIH/SUS). Probabilistic linkage was used to combine multiple AIH forms from the same admission into a single record and to identify readmissions. Information on prescriptions was manually added to the SIH/SUS records. Logistic regression was used to quantitatively assess the impact of drug interactions on hospital readmissions. Cox regression was performed to test the impact of this variable on time to first readmission. RESULTS: A total of 99 readmissions (7% of all patients) were identified. Potential drug interactions were found in 35% of all prescriptions evaluated. Patients with potential drug interactions in a prior admission were more likely to be readmitted. The adjusted odds ratio indicated a 2.4-fold increase in odds of being readmitted; and the adjusted hazard ratio showed that this risk was increased by 79% in patients with potential drug interactions (p < 0.01). CONCLUSIONS: The study results suggest an association between prior drug interactions and increased risk of readmission. Health professionals should be aware of potential hazard of certain drug combinations and closely monitor high-risk patients such as elderly patients and those with renal impairment.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-05-06T13:19:50Z No. of bitstreams: 1 Cristiano Soares de Moura.pdf: 53365 bytes, checksum: cd6b38dcde735fbce7c4f54c1502e117 (MD5)Made available in DSpace on 2014-05-06T13:19:50Z (GMT). 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dc.title.pt_BR.fl_str_mv Hospital readmissions related to drug interactions: a retrospective study in a hospital setting
dc.title.alternative.pt_BR.fl_str_mv Revista de Saúde Pública
title Hospital readmissions related to drug interactions: a retrospective study in a hospital setting
spellingShingle Hospital readmissions related to drug interactions: a retrospective study in a hospital setting
Moura, Cristiano Soares de
Patient Readmission
Drug Interactions
Hospitalization
Adverse effects
Polypharmacy
title_short Hospital readmissions related to drug interactions: a retrospective study in a hospital setting
title_full Hospital readmissions related to drug interactions: a retrospective study in a hospital setting
title_fullStr Hospital readmissions related to drug interactions: a retrospective study in a hospital setting
title_full_unstemmed Hospital readmissions related to drug interactions: a retrospective study in a hospital setting
title_sort Hospital readmissions related to drug interactions: a retrospective study in a hospital setting
author Moura, Cristiano Soares de
author_facet Moura, Cristiano Soares de
Tavares, Ludmila Santana
Acurcio, Francisco de Assis
author_role author
author2 Tavares, Ludmila Santana
Acurcio, Francisco de Assis
author2_role author
author
dc.contributor.author.fl_str_mv Moura, Cristiano Soares de
Tavares, Ludmila Santana
Acurcio, Francisco de Assis
Moura, Cristiano Soares de
Tavares, Ludmila Santana
Acurcio, Francisco de Assis
dc.subject.por.fl_str_mv Patient Readmission
Drug Interactions
Hospitalization
Adverse effects
Polypharmacy
topic Patient Readmission
Drug Interactions
Hospitalization
Adverse effects
Polypharmacy
description p. 1-7
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-05-06T13:19:50Z
dc.date.available.fl_str_mv 2014-05-06T13:19:50Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/14907
dc.identifier.issn.none.fl_str_mv 0034-8910,
dc.identifier.number.pt_BR.fl_str_mv v. 46, n. 6
identifier_str_mv 0034-8910,
v. 46, n. 6
url http://repositorio.ufba.br/ri/handle/ri/14907
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.country.fl_str_mv Brasil
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S0034-89102013005000001
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instacron_str UFBA
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reponame_str Repositório Institucional da UFBA
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