Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
Autor(a) principal: | |
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Data de Publicação: | 1982 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/8633 |
Resumo: | Texto completo. Acesso restrito. p. 847 - 853 |
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Repositório Institucional da UFBA |
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1932 |
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Novaes, GeóvanaCatanzaro, O. L.Beraldo, W. T.Maia, L. FreireNovaes, GeóvanaCatanzaro, O. L.Beraldo, W. T.Maia, L. Freire2013-02-21T19:10:48Z2013-02-21T19:10:48Z19820041-0101http://www.repositorio.ufba.br/ri/handle/ri/8633v. 20, n. 5Texto completo. Acesso restrito. p. 847 - 853Effect of purified scorpion torin (tityustorin) on the pancreatic secretion of the rat. Toxicon 20, 847-853, 1982.- Intravenous injection, in anesthetized rata, ofa single dose of purified scorpion toxin(tityustoxin, TsT~, obtained from the venom of the Brazilian scorpion Tityus serrulatus, causes a striking increase in fbw rate, protein content, kallikrein andamylase activities of the pancreatic juice. The Howrate andprotein contentof thejuice remain significantly higher than in control rats,forat least one hour, whereas thekallilaein activity returns to control values 30minaftertityustorin injection. Sub-diaphragmatic bilateral vagotomy does notpreventthe pancreatic secretioninducedby tityustoxin; moreover, vagotomy potentiates the flow rate and kallikrein secretion produced by the torin. Pre-treatmentof the rats with atropine blocks thepancreatic secretion evoked by tityustorin. It is suggestedthat the pancreatic secretion inducedbytityustorinis dueto actions of acetylcholine, released from postganglionic nerve fibers, on muscarinic receptors. The mechanism by which vagotomy potentiatea the pancreatic secretion evoked by tityustorin is under investigationSubmitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-02-21T19:10:48Z No. of bitstreams: 1 222222.pdf: 391109 bytes, checksum: 96db46609618f21941305583d125e93e (MD5)Made available in DSpace on 2013-02-21T19:10:48Z (GMT). No. of bitstreams: 1 222222.pdf: 391109 bytes, checksum: 96db46609618f21941305583d125e93e (MD5) Previous issue date: 1982SalvadorToxiconhttp://dx.doi.org/10.1016/0041-0101(82)90072-1reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAEffect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the ratToxiconinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL222222.pdf222222.pdfapplication/pdf391109https://repositorio.ufba.br/bitstream/ri/8633/1/222222.pdf96db46609618f21941305583d125e93eMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/8633/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT222222.pdf.txt222222.pdf.txtExtracted texttext/plain7https://repositorio.ufba.br/bitstream/ri/8633/3/222222.pdf.txt212b0306580d4f0044d18f9a3edcc832MD53ri/86332022-07-05 14:03:42.921oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:42Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat |
dc.title.alternative.pt_BR.fl_str_mv |
Toxicon |
title |
Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat |
spellingShingle |
Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat Novaes, Geóvana |
title_short |
Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat |
title_full |
Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat |
title_fullStr |
Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat |
title_full_unstemmed |
Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat |
title_sort |
Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat |
author |
Novaes, Geóvana |
author_facet |
Novaes, Geóvana Catanzaro, O. L. Beraldo, W. T. Maia, L. Freire |
author_role |
author |
author2 |
Catanzaro, O. L. Beraldo, W. T. Maia, L. Freire |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Novaes, Geóvana Catanzaro, O. L. Beraldo, W. T. Maia, L. Freire Novaes, Geóvana Catanzaro, O. L. Beraldo, W. T. Maia, L. Freire |
description |
Texto completo. Acesso restrito. p. 847 - 853 |
publishDate |
1982 |
dc.date.issued.fl_str_mv |
1982 |
dc.date.accessioned.fl_str_mv |
2013-02-21T19:10:48Z |
dc.date.available.fl_str_mv |
2013-02-21T19:10:48Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/8633 |
dc.identifier.issn.none.fl_str_mv |
0041-0101 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 20, n. 5 |
identifier_str_mv |
0041-0101 v. 20, n. 5 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/8633 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Toxicon |
publisher.none.fl_str_mv |
Toxicon |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/10.1016/0041-0101(82)90072-1 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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