Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat

Detalhes bibliográficos
Autor(a) principal: Novaes, Geóvana
Data de Publicação: 1982
Outros Autores: Catanzaro, O. L., Beraldo, W. T., Maia, L. Freire
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/8633
Resumo: Texto completo. Acesso restrito. p. 847 - 853
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spelling Novaes, GeóvanaCatanzaro, O. L.Beraldo, W. T.Maia, L. FreireNovaes, GeóvanaCatanzaro, O. L.Beraldo, W. T.Maia, L. Freire2013-02-21T19:10:48Z2013-02-21T19:10:48Z19820041-0101http://www.repositorio.ufba.br/ri/handle/ri/8633v. 20, n. 5Texto completo. Acesso restrito. p. 847 - 853Effect of purified scorpion torin (tityustorin) on the pancreatic secretion of the rat. Toxicon 20, 847-853, 1982.- Intravenous injection, in anesthetized rata, ofa single dose of purified scorpion toxin(tityustoxin, TsT~, obtained from the venom of the Brazilian scorpion Tityus serrulatus, causes a striking increase in fbw rate, protein content, kallikrein andamylase activities of the pancreatic juice. The Howrate andprotein contentof thejuice remain significantly higher than in control rats,forat least one hour, whereas thekallilaein activity returns to control values 30minaftertityustorin injection. Sub-diaphragmatic bilateral vagotomy does notpreventthe pancreatic secretioninducedby tityustoxin; moreover, vagotomy potentiates the flow rate and kallikrein secretion produced by the torin. Pre-treatmentof the rats with atropine blocks thepancreatic secretion evoked by tityustorin. It is suggestedthat the pancreatic secretion inducedbytityustorinis dueto actions of acetylcholine, released from postganglionic nerve fibers, on muscarinic receptors. The mechanism by which vagotomy potentiatea the pancreatic secretion evoked by tityustorin is under investigationSubmitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-02-21T19:10:48Z No. of bitstreams: 1 222222.pdf: 391109 bytes, checksum: 96db46609618f21941305583d125e93e (MD5)Made available in DSpace on 2013-02-21T19:10:48Z (GMT). No. of bitstreams: 1 222222.pdf: 391109 bytes, checksum: 96db46609618f21941305583d125e93e (MD5) Previous issue date: 1982SalvadorToxiconhttp://dx.doi.org/10.1016/0041-0101(82)90072-1reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAEffect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the ratToxiconinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL222222.pdf222222.pdfapplication/pdf391109https://repositorio.ufba.br/bitstream/ri/8633/1/222222.pdf96db46609618f21941305583d125e93eMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/8633/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT222222.pdf.txt222222.pdf.txtExtracted texttext/plain7https://repositorio.ufba.br/bitstream/ri/8633/3/222222.pdf.txt212b0306580d4f0044d18f9a3edcc832MD53ri/86332022-07-05 14:03:42.921oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:42Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
dc.title.alternative.pt_BR.fl_str_mv Toxicon
title Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
spellingShingle Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
Novaes, Geóvana
title_short Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
title_full Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
title_fullStr Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
title_full_unstemmed Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
title_sort Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat
author Novaes, Geóvana
author_facet Novaes, Geóvana
Catanzaro, O. L.
Beraldo, W. T.
Maia, L. Freire
author_role author
author2 Catanzaro, O. L.
Beraldo, W. T.
Maia, L. Freire
author2_role author
author
author
dc.contributor.author.fl_str_mv Novaes, Geóvana
Catanzaro, O. L.
Beraldo, W. T.
Maia, L. Freire
Novaes, Geóvana
Catanzaro, O. L.
Beraldo, W. T.
Maia, L. Freire
description Texto completo. Acesso restrito. p. 847 - 853
publishDate 1982
dc.date.issued.fl_str_mv 1982
dc.date.accessioned.fl_str_mv 2013-02-21T19:10:48Z
dc.date.available.fl_str_mv 2013-02-21T19:10:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/8633
dc.identifier.issn.none.fl_str_mv 0041-0101
dc.identifier.number.pt_BR.fl_str_mv v. 20, n. 5
identifier_str_mv 0041-0101
v. 20, n. 5
url http://www.repositorio.ufba.br/ri/handle/ri/8633
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Toxicon
publisher.none.fl_str_mv Toxicon
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/0041-0101(82)90072-1
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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