Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/4802 |
Resumo: | P. 192-198,Mar./Apr. |
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Granato, Ana ClaudiaOliveira, Jaine H. H. L. deSeleghim, Mirna Helena RegaliBerlinck, Roberto Gomes de SouzaMacedo, Mario L.Ferreira, Antonio G.Rocha, Rosana M. daHajdu, EduardoPeixinho, SolangePessoa, Claudia O.Moraes, Manoel O.Cavalcanti, Bruno CoêlhoGranato, Ana ClaudiaOliveira, Jaine H. H. L. deSeleghim, Mirna Helena RegaliBerlinck, Roberto Gomes de SouzaMacedo, Mario L.Ferreira, Antonio G.Rocha, Rosana M. daHajdu, EduardoPeixinho, SolangePessoa, Claudia O.Moraes, Manoel O.Cavalcanti, Bruno Coêlho2011-12-12T12:22:53Z2011-12-12T12:22:53Z20050100-4042http://www.repositorio.ufba.br/ri/handle/ri/4802v. 28, n. 2.P. 192-198,Mar./Apr.Two new marine metabolites, 3Z, 6Z, 9Z-dodecatrien-1-ol (1) from the ascidian Botrylloides giganteum and 4H-pyran-2ol acetate from the sponge Ircinia felix (4) are herein reported. The known bromotyrosine compounds, 2-(3,5-dibromo-4-methoxyphenyl)-N,N,N-dimethylethanammonium (2) and 2,6-dibromo-4-(2-(trimethylammonium)ethyl)phenol (3), have been isolated from the sponge Verongula gigantea. Serotonin (5) is reported for the first time from the sponge Cliona delitrix, and tambjamines A (15) and D (16) isolated as their respective salts from the nudibranch Tambja eliora. Only tambjamine D presented cytotoxicity against CEM (IC50 12.2 µg/mL) and HL60 (IC50 13.2 µg/mL) human leukemya cells, MCF-7 breast cancer cells (IC50 13.2 µg/mL), colon HCT-8 cancer cells (IC50 10.1 µg/mL) and murine melanoma B16 cancer cells (IC50 6.7 µg/mL).Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2011-12-12T12:22:53Z No. of bitstreams: 1 23636.pdf: 115260 bytes, checksum: 29bb2d07a31c954c541a4ac726b5e8f7 (MD5)Made available in DSpace on 2011-12-12T12:22:53Z (GMT). No. of bitstreams: 1 23636.pdf: 115260 bytes, checksum: 29bb2d07a31c954c541a4ac726b5e8f7 (MD5) Previous issue date: 2005São Paulohttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422005000200005&lng=en&nrm=isoreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAMarine spongeNudibranchAscidianProdutos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do BrasilQuímica Novainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleporinfo:eu-repo/semantics/openAccessORIGINAL23636.pdf23636.pdfapplication/pdf115260https://repositorio.ufba.br/bitstream/ri/4802/1/23636.pdf29bb2d07a31c954c541a4ac726b5e8f7MD51LICENSElicense.txtlicense.txttext/plain1748https://repositorio.ufba.br/bitstream/ri/4802/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXT23636.pdf.txt23636.pdf.txtExtracted texttext/plain47570https://repositorio.ufba.br/bitstream/ri/4802/3/23636.pdf.txt03de1668cce023c93d667e004b476ef9MD53ri/48022022-07-05 14:03:16.541oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:16Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil |
dc.title.alternative.pt_BR.fl_str_mv |
Química Nova |
title |
Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil |
spellingShingle |
Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil Granato, Ana Claudia Marine sponge Nudibranch Ascidian |
title_short |
Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil |
title_full |
Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil |
title_fullStr |
Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil |
title_full_unstemmed |
Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil |
title_sort |
Produtos naturais da ascídia Botrylloides giganteum, das esponjas Verongula gigantea, Ircinia felix, Cliona delitrix e do nudibrânquio Tambja eliora, da costa do Brasil |
author |
Granato, Ana Claudia |
author_facet |
Granato, Ana Claudia Oliveira, Jaine H. H. L. de Seleghim, Mirna Helena Regali Berlinck, Roberto Gomes de Souza Macedo, Mario L. Ferreira, Antonio G. Rocha, Rosana M. da Hajdu, Eduardo Peixinho, Solange Pessoa, Claudia O. Moraes, Manoel O. Cavalcanti, Bruno Coêlho |
author_role |
author |
author2 |
Oliveira, Jaine H. H. L. de Seleghim, Mirna Helena Regali Berlinck, Roberto Gomes de Souza Macedo, Mario L. Ferreira, Antonio G. Rocha, Rosana M. da Hajdu, Eduardo Peixinho, Solange Pessoa, Claudia O. Moraes, Manoel O. Cavalcanti, Bruno Coêlho |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Granato, Ana Claudia Oliveira, Jaine H. H. L. de Seleghim, Mirna Helena Regali Berlinck, Roberto Gomes de Souza Macedo, Mario L. Ferreira, Antonio G. Rocha, Rosana M. da Hajdu, Eduardo Peixinho, Solange Pessoa, Claudia O. Moraes, Manoel O. Cavalcanti, Bruno Coêlho Granato, Ana Claudia Oliveira, Jaine H. H. L. de Seleghim, Mirna Helena Regali Berlinck, Roberto Gomes de Souza Macedo, Mario L. Ferreira, Antonio G. Rocha, Rosana M. da Hajdu, Eduardo Peixinho, Solange Pessoa, Claudia O. Moraes, Manoel O. Cavalcanti, Bruno Coêlho |
dc.subject.por.fl_str_mv |
Marine sponge Nudibranch Ascidian |
topic |
Marine sponge Nudibranch Ascidian |
description |
P. 192-198,Mar./Apr. |
publishDate |
2005 |
dc.date.issued.fl_str_mv |
2005 |
dc.date.accessioned.fl_str_mv |
2011-12-12T12:22:53Z |
dc.date.available.fl_str_mv |
2011-12-12T12:22:53Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
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publishedVersion |
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http://www.repositorio.ufba.br/ri/handle/ri/4802 |
dc.identifier.issn.none.fl_str_mv |
0100-4042 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 28, n. 2. |
identifier_str_mv |
0100-4042 v. 28, n. 2. |
url |
http://www.repositorio.ufba.br/ri/handle/ri/4802 |
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por |
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por |
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info:eu-repo/semantics/openAccess |
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openAccess |
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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422005000200005&lng=en&nrm=iso |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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