Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/5427 |
Resumo: | Acesso restrito: Texto completo. p. 566–571. |
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Rodrigues Filhoa, GuimesRibeiro, Sabrina DiasMeireles, Carla da SilvaSilva, Leandro Gustavo daRuggiero, ReinaldoFerreira Júnior, Moacir FernandesCerqueira, Daniel AlvesAssunção, Rosana Maria Nascimento deZeni, MaraPolleto, PatriciaRodrigues Filhoa, GuimesRibeiro, Sabrina DiasMeireles, Carla da SilvaSilva, Leandro Gustavo daRuggiero, ReinaldoFerreira Júnior, Moacir FernandesCerqueira, Daniel AlvesAssunção, Rosana Maria Nascimento deZeni, MaraPolleto, Patricia2012-02-24T10:50:19Z2011-050926-6690http://www.repositorio.ufba.br/ri/handle/ri/5427v. 33, n. 3.Acesso restrito: Texto completo. p. 566–571.Cellulose acetate is one of the components employed in drug controlled-release systems in the form of membranes. The aim of this study was to examine the controlled-release of doxycycline employing cellulose acetate symmetric and asymmetric membranes as matrices. The cellulose triacetate was produced from sugarcane bagasse through a homogeneous acetylation reaction, using acetic acid as the solvent,acetic anhydride as the acetylating agent and sulfuric acid as the catalyst. The viscosity average molecular weight of the cellulose acetate produced was 39,000 g mol−1. The symmetric membranes were produced using a system solvent of dichloromethane/ethanol (9:1, v/v) and the asymmetric membranes were produced from the same solvent system and 10% of water. For the formulation of both, 5% of doxycycline was used. The membranes were characterized by thermal analysis (DSC and TGA) and scanning electron microscopy SEM. The release of doxycycline through cellulose triacetate matrices was examined using spectrophotometric analysis in the ultraviolet–visible region, at 275 nm. The results revealed that asymmetric membranes release 80% of the drug in 100 min, while symmetric membranes release 14% of the drug during the same time interval.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-02-24T10:50:19Z No. of bitstreams: 1 __pdn.sciencedirect.com_....0-S0926669010002827-main.pdf: 299695 bytes, checksum: e7f9c64493ab9cd5535802349aa9772b (MD5)Made available in DSpace on 2012-02-24T10:50:19Z (GMT). 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| dc.title.pt_BR.fl_str_mv |
Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse |
| dc.title.alternative.pt_BR.fl_str_mv |
Industrial Crops and Products |
| title |
Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse |
| spellingShingle |
Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse Rodrigues Filhoa, Guimes Controlled-release Doxycycline Cellulose triacetate Sugarcane bagasse Symmetric and asymmetric membranes |
| title_short |
Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse |
| title_full |
Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse |
| title_fullStr |
Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse |
| title_full_unstemmed |
Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse |
| title_sort |
Release of doxycycline through cellulose acetate symmetric and asymmetric membranes produced from recycled agroindustrial residue: Sugarcane bagasse |
| author |
Rodrigues Filhoa, Guimes |
| author_facet |
Rodrigues Filhoa, Guimes Ribeiro, Sabrina Dias Meireles, Carla da Silva Silva, Leandro Gustavo da Ruggiero, Reinaldo Ferreira Júnior, Moacir Fernandes Cerqueira, Daniel Alves Assunção, Rosana Maria Nascimento de Zeni, Mara Polleto, Patricia |
| author_role |
author |
| author2 |
Ribeiro, Sabrina Dias Meireles, Carla da Silva Silva, Leandro Gustavo da Ruggiero, Reinaldo Ferreira Júnior, Moacir Fernandes Cerqueira, Daniel Alves Assunção, Rosana Maria Nascimento de Zeni, Mara Polleto, Patricia |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Rodrigues Filhoa, Guimes Ribeiro, Sabrina Dias Meireles, Carla da Silva Silva, Leandro Gustavo da Ruggiero, Reinaldo Ferreira Júnior, Moacir Fernandes Cerqueira, Daniel Alves Assunção, Rosana Maria Nascimento de Zeni, Mara Polleto, Patricia Rodrigues Filhoa, Guimes Ribeiro, Sabrina Dias Meireles, Carla da Silva Silva, Leandro Gustavo da Ruggiero, Reinaldo Ferreira Júnior, Moacir Fernandes Cerqueira, Daniel Alves Assunção, Rosana Maria Nascimento de Zeni, Mara Polleto, Patricia |
| dc.subject.por.fl_str_mv |
Controlled-release Doxycycline Cellulose triacetate Sugarcane bagasse Symmetric and asymmetric membranes |
| topic |
Controlled-release Doxycycline Cellulose triacetate Sugarcane bagasse Symmetric and asymmetric membranes |
| description |
Acesso restrito: Texto completo. p. 566–571. |
| publishDate |
2011 |
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2011-05 |
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2012-02-24T10:50:19Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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http://www.repositorio.ufba.br/ri/handle/ri/5427 |
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0926-6690 |
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v. 33, n. 3. |
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0926-6690 v. 33, n. 3. |
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http://www.repositorio.ufba.br/ri/handle/ri/5427 |
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DOI: 10.1016/j.indcrop.2010.10.037 |
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