Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients

Detalhes bibliográficos
Autor(a) principal: Brites, Carlos
Data de Publicação: 2011
Outros Autores: Martins Netto, Eduardo, Jorge, Célia Regina Mayoral Pedroso, Sampaio, Diana Brasil Pedral, Harrington Júnior, W., Goyanna, F., Adriano, S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5268
Resumo: p. 6-11
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spelling Brites, CarlosMartins Netto, EduardoJorge, Célia Regina Mayoral PedrosoSampaio, Diana Brasil PedralHarrington Júnior, W.Goyanna, F.Adriano, S.Brites, CarlosMartins Netto, EduardoJorge, Célia Regina Mayoral PedrosoSampaio, Diana Brasil PedralHarrington Júnior, W.Goyanna, F.Adriano, S.2012-01-27T12:06:33Z2012-01-27T12:06:33Z20111678-4391http://www.repositorio.ufba.br/ri/handle/ri/526815(1)p. 6-11Objective: To compare the clinical characteristics and outcomes of HIV-1-HTLV-1 coinfected patients, in Bahia, Brazil. Methods: Retrospective, comparative study. Results: Among a total of 123 consecutive HIV infected patients, 20 men (20.6%) and 6 women (23.1%) had detectable antibodies against HTLV-I/II. The major risk factor associated with coinfection by HTLV was intravenous drug use (57.7% of coinfected patient versus 9.2% of HTLV seronegative patients, p < 0.0001). Coinfected patients had higher absolute lymphocyte counts (1,921 + 762 versus 1,587 + 951, p = 0.03). Both groups of patients had similar means of CD4+ and CD8+ cell counts. However, among patients with AIDS CD4+ cell counts were signifi cantly higher among those coinfected with HTLV-I/II (292 ± 92 cells/mm3, versus 140 ± 177cells/mm3, p = 0.36). The frequency and type of opportunistic infections were similar for both groups, but strongyloidiasis and encephalopathy were more frequently diagnosed in coinfected patients (p < 0.05). On the other hand, patients coinfected with HTLV-I/II received signifi cantly less antiretroviral therapy than singly infected by HIV-1. Conclusion: Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis for HIV patients. Higher CD4 count may lead to underestimation of immunodefi ciency, and delay to initiate antiretroviral therapy.Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-01-27T12:06:32Z No. of bitstreams: 1 v15n1a02.pdf: 292022 bytes, checksum: f28cb05dd0bc465f62b993e2b6451930 (MD5)Made available in DSpace on 2012-01-27T12:06:33Z (GMT). No. of bitstreams: 1 v15n1a02.pdf: 292022 bytes, checksum: f28cb05dd0bc465f62b993e2b6451930 (MD5) Previous issue date: 2011HIVHTLV-I/IIcoinfection StrongyloidiasisCD4/CD8Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patientsThe Brazilian Journal of Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINALv15n1a02.pdfv15n1a02.pdfapplication/pdf292022https://repositorio.ufba.br/bitstream/ri/5268/1/v15n1a02.pdff28cb05dd0bc465f62b993e2b6451930MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5268/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTv15n1a02.pdf.txtv15n1a02.pdf.txtExtracted texttext/plain28945https://repositorio.ufba.br/bitstream/ri/5268/3/v15n1a02.pdf.txtcc4dcd0d50772c0a8082cce543ba5400MD53ri/52682022-07-05 14:03:47.579oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:47Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
dc.title.alternative.pt_BR.fl_str_mv The Brazilian Journal of Infectious Diseases
title Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
spellingShingle Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
Brites, Carlos
HIV
HTLV-I/II
coinfection Strongyloidiasis
CD4/CD8
title_short Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
title_full Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
title_fullStr Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
title_full_unstemmed Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
title_sort Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
author Brites, Carlos
author_facet Brites, Carlos
Martins Netto, Eduardo
Jorge, Célia Regina Mayoral Pedroso
Sampaio, Diana Brasil Pedral
Harrington Júnior, W.
Goyanna, F.
Adriano, S.
author_role author
author2 Martins Netto, Eduardo
Jorge, Célia Regina Mayoral Pedroso
Sampaio, Diana Brasil Pedral
Harrington Júnior, W.
Goyanna, F.
Adriano, S.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Brites, Carlos
Martins Netto, Eduardo
Jorge, Célia Regina Mayoral Pedroso
Sampaio, Diana Brasil Pedral
Harrington Júnior, W.
Goyanna, F.
Adriano, S.
Brites, Carlos
Martins Netto, Eduardo
Jorge, Célia Regina Mayoral Pedroso
Sampaio, Diana Brasil Pedral
Harrington Júnior, W.
Goyanna, F.
Adriano, S.
dc.subject.por.fl_str_mv HIV
HTLV-I/II
coinfection Strongyloidiasis
CD4/CD8
topic HIV
HTLV-I/II
coinfection Strongyloidiasis
CD4/CD8
description p. 6-11
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2012-01-27T12:06:33Z
dc.date.available.fl_str_mv 2012-01-27T12:06:33Z
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dc.identifier.issn.none.fl_str_mv 1678-4391
dc.identifier.number.pt_BR.fl_str_mv 15(1)
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dc.language.iso.fl_str_mv eng
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