Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle

Detalhes bibliográficos
Autor(a) principal: Gomes, Rodrigo da Costa
Data de Publicação: 2013
Outros Autores: Silva, Saulo da Luz e, Carvalho, Minos Esperandio, Rezende, Fernanda Marcondes de, Pinto, Luis Fernando Batista, Santana, Miguel Henrique de Almeida, Stella, Tiago Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15713
Resumo: p. 2923-2936
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spelling Gomes, Rodrigo da CostaSilva, Saulo da Luz eCarvalho, Minos EsperandioRezende, Fernanda Marcondes dePinto, Luis Fernando BatistaSantana, Miguel Henrique de AlmeidaStella, Tiago RobertoGomes, Rodrigo da CostaSilva, Saulo da Luz eCarvalho, Minos EsperandioRezende, Fernanda Marcondes dePinto, Luis Fernando BatistaSantana, Miguel Henrique de AlmeidaStella, Tiago Roberto2014-08-26T18:29:56Z2014-08-26T18:29:56Z20131676-5680http://repositorio.ufba.br/ri/handle/ri/15713v. 12, n. 3p. 2923-2936We looked for possible associations of SNPs in genes related to protein turnover, with growth, feed efficiency and carcass traits in feedlot Nellore cattle. Purebred Nellore bulls and steers (N = 290; 378 ± 42 kg body weight, 23 months ± 42 days old) were evaluated for daily feed intake, body weight gain (BWG), gross feed efficiency, feed conversion ratio, partial efficiency of growth, residual feed intake (RFI), ultrasound backfat, rump fat, and ribeye area. Genotypes were obtained for SNPs in the growth hormone receptor (GHR-1 and GHR-2); calpain (CAPN4751); calpastatin (UoGCAST); ubiquitin-conjugating enzyme 2I (UBE2I-1 and UBE2I-2); R3H domain containing 1 (R3HDM1-1, -2, -3, and -4), ring finger protein 19 (RNF19); proteasome 26S subunit, non-ATPase, 13 (PSMD13); ribosomal protein, large, P2 (RPLP2); and isoleucine-tRNA synthetase 2, mitochondrial (IARS2) genes. Allelic substitution, additive and dominant effects were tested and molecular breeding values were computed. CAPN4751, GHR-1 and -2, IARS2, R3HDM1-4, and UoGCAST were found to be normally segregating polymorphisms. Additive and dominance effects were observed on BWG, feed efficiency and carcass traits, although dominant effects predominated. Significant allelic substitution effects were observed for CAPN4751, GHR-1 and -2, and UoGCAST on BWG, gross feed efficiency, RFI, and carcass traits, under single- or multiple-marker analyses. Correlations between molecular breeding values and phenotypes were low, excepted for RFI, based on allelic substitution estimates obtained by stepwise linear regression. We conclude that SNPs in genes related to protein turnover are related to economically important traits in Nellore cattle.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-05-13T12:21:42Z No. of bitstreams: 1 10.4238-2013.August.12.8.pdf: 376329 bytes, checksum: 99924bf5ac6a8101ed37b25df28ce073 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-08-26T18:29:56Z (GMT) No. of bitstreams: 1 10.4238-2013.August.12.8.pdf: 376329 bytes, checksum: 99924bf5ac6a8101ed37b25df28ce073 (MD5)Made available in DSpace on 2014-08-26T18:29:56Z (GMT). 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dc.title.pt_BR.fl_str_mv Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle
dc.title.alternative.pt_BR.fl_str_mv Genetics and molecular research : GMR
title Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle
spellingShingle Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle
Gomes, Rodrigo da Costa
Bos indicus
Marker-assisted selection
Molecular breeding value
Protein turnover
Residual feed intake
title_short Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle
title_full Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle
title_fullStr Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle
title_full_unstemmed Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle
title_sort Protein synthesis and degradation gene SNPs related to feed intake, feed efficiency, growth, and ultrasound carcass traits in Nellore cattle
author Gomes, Rodrigo da Costa
author_facet Gomes, Rodrigo da Costa
Silva, Saulo da Luz e
Carvalho, Minos Esperandio
Rezende, Fernanda Marcondes de
Pinto, Luis Fernando Batista
Santana, Miguel Henrique de Almeida
Stella, Tiago Roberto
author_role author
author2 Silva, Saulo da Luz e
Carvalho, Minos Esperandio
Rezende, Fernanda Marcondes de
Pinto, Luis Fernando Batista
Santana, Miguel Henrique de Almeida
Stella, Tiago Roberto
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gomes, Rodrigo da Costa
Silva, Saulo da Luz e
Carvalho, Minos Esperandio
Rezende, Fernanda Marcondes de
Pinto, Luis Fernando Batista
Santana, Miguel Henrique de Almeida
Stella, Tiago Roberto
Gomes, Rodrigo da Costa
Silva, Saulo da Luz e
Carvalho, Minos Esperandio
Rezende, Fernanda Marcondes de
Pinto, Luis Fernando Batista
Santana, Miguel Henrique de Almeida
Stella, Tiago Roberto
dc.subject.por.fl_str_mv Bos indicus
Marker-assisted selection
Molecular breeding value
Protein turnover
Residual feed intake
topic Bos indicus
Marker-assisted selection
Molecular breeding value
Protein turnover
Residual feed intake
description p. 2923-2936
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-08-26T18:29:56Z
dc.date.available.fl_str_mv 2014-08-26T18:29:56Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15713
dc.identifier.issn.none.fl_str_mv 1676-5680
dc.identifier.number.pt_BR.fl_str_mv v. 12, n. 3
identifier_str_mv 1676-5680
v. 12, n. 3
url http://repositorio.ufba.br/ri/handle/ri/15713
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.country.fl_str_mv Brasil
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.4238/2013.August.12.8
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