Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi

Detalhes bibliográficos
Autor(a) principal: Andrade, Sonia Gumes
Data de Publicação: 1994
Outros Autores: Magalhães, Juracy B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5051
Resumo: p.481-484
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spelling Andrade, Sonia GumesMagalhães, Juracy B.Andrade, Sonia GumesMagalhães, Juracy B.2012-01-06T13:14:09Z2012-01-06T13:14:09Z19941678-9946http://www.repositorio.ufba.br/ri/handle/ri/5051v. 36, n. 6.p.481-484Seventy Swiss mice chronically infected with different strains of Trypanosoma cruzi, with persistentiy negative parasitemia on routine blood examination were parasitologicaily investigated to find out whether spontaneous cure occurred. Duration of infection varied from 90 to 250 days in the initial phase of this investigation. Parasitologicai tests consisted of daily direct blood examination performed during at least 25 days, foliowed by xenodiagnosis and subinocuiation of blood into newborn mice. Mice that persisted negative were treated with Cyciophosphamide with one dose of 250 mg!kg of body weight and then investigated by direct blood examination, xenodiagnosis and subinoculation. A second dose of 250 mgfkg b. w. was given to the persistentiy negative mice. With one single exception, ali mice showed positive parasitoiogicai tests in the different stages ofthe present investigation and we conciude that spontaneous cure did not occur in this group, which is representa- tive of the chronic infection with different strains of T. cruzi.Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-01-06T13:14:09Z No. of bitstreams: 1 a01v36n6.pdf: 236049 bytes, checksum: 60b3a1c6a780a7c2b85b1810871dd325 (MD5)Made available in DSpace on 2012-01-06T13:14:09Z (GMT). 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dc.title.pt_BR.fl_str_mv Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi
dc.title.alternative.pt_BR.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo
title Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi
spellingShingle Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi
Andrade, Sonia Gumes
Trypanosoma cruzi
Spontaneous cure
Chronic infection
Murine modei
Cyciophosphamide
title_short Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi
title_full Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi
title_fullStr Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi
title_full_unstemmed Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi
title_sort Investigation on the possibility of spontaneous cure of mice infected with different strains of Trypanosoma cruzi
author Andrade, Sonia Gumes
author_facet Andrade, Sonia Gumes
Magalhães, Juracy B.
author_role author
author2 Magalhães, Juracy B.
author2_role author
dc.contributor.author.fl_str_mv Andrade, Sonia Gumes
Magalhães, Juracy B.
Andrade, Sonia Gumes
Magalhães, Juracy B.
dc.subject.por.fl_str_mv Trypanosoma cruzi
Spontaneous cure
Chronic infection
Murine modei
Cyciophosphamide
topic Trypanosoma cruzi
Spontaneous cure
Chronic infection
Murine modei
Cyciophosphamide
description p.481-484
publishDate 1994
dc.date.issued.fl_str_mv 1994
dc.date.accessioned.fl_str_mv 2012-01-06T13:14:09Z
dc.date.available.fl_str_mv 2012-01-06T13:14:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5051
dc.identifier.issn.none.fl_str_mv 1678-9946
dc.identifier.number.pt_BR.fl_str_mv v. 36, n. 6.
identifier_str_mv 1678-9946
v. 36, n. 6.
url http://www.repositorio.ufba.br/ri/handle/ri/5051
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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