Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results

Detalhes bibliográficos
Autor(a) principal: Oliveira, Rogério Jorge Barbosa de
Data de Publicação: 2013
Outros Autores: Santos, Ana Paula Caires dos, Santos Junior, Lázaro Silveira, Vieira, Marcos Soares, Aras Júnior, Roque, Couto, Fábio David, Couto, Ricardo David
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/17526
Resumo: p.18-24
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spelling Oliveira, Rogério Jorge Barbosa deSantos, Ana Paula Caires dosSantos Junior, Lázaro SilveiraVieira, Marcos SoaresAras Júnior, RoqueCouto, Fábio DavidCouto, Ricardo DavidOliveira, Rogério Jorge Barbosa deSantos, Ana Paula Caires dosSantos Junior, Lázaro SilveiraVieira, Marcos SoaresAras Júnior, RoqueCouto, Fábio DavidCouto, Ricardo David2015-05-04T15:36:58Z2015-05-04T15:36:58Z20131676-2444http://repositorio.ufba.br/ri/handle/ri/17526v. 49, n. 1p.18-24INTRODUCTION: Atherosclerosis and correlated cardiovascular problems, whose mechanical and physiological disorders cause thickening and hardening of blood vessels, are among the main causes of death worldwide. OBJECTIVE: To assess plasma concentrations of biomarkers from the lipid metabolism and carotid doppler sonography results by correlating them with atherogenic carotid disease. METHODS: the study comprised 66 patients aged 57.5 ± 15.5 years (20-77), from which 63% were female. Serum markers and doppler sonography images were used to evaluate the association with atherogenic carotid disease (ACD). RESULTS: There was a higher prevalence of ACD among females (33% vs. 15%), age range 56-65, showing a relative risk (RR) of 1.56 among females (p < 0.002; Fisher, Katz). Concerning high density lipoprotein cholesterol (HDL-C) and carotid stenosis classification, North American Symptomatic Carotid Endarterectomy Trial (NASCET), 76% of patients showed HDL-C within the protection range, from which 31 individuals presented level I (normal). 81% of them showed HDL-C > 40 mg/dl and 19% had HDL-C ≥ 40 mg/dl. The prevalence of HDL-C > 40 mg/dl at levels II, III and IV was considerable. There was no difference in HDL-C among the groups (p = 0.4910; unpaired t test). Furthermore, there was no difference in paraoxonase (PON1) activity when stratified to HDL-C > and < 40 mg/dl (p > 0.05). CONCLUSION: The female group displayed higher ACD prevalence at 56-65 age range, with RR of 1.56 times higher. These findings substantiate the importance of analyzing this group and age range carefully, inasmuch as the absence of hormonal protection may increase ACD risk and ultimately influence HDL antioxidant activity due to its direct action on PON1. Triglycerides (TG)/HDL-C ratio indicates cardiovascular risk and impaired reverse cholesterol transport.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2015-03-17T13:15:59Z No. of bitstreams: 1 Rogério Jorge Barbosa de Oliveira.pdf: 167540 bytes, checksum: d50995c35ae00f50bcfd54a8af8e854a (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-05-04T15:36:58Z (GMT) No. of bitstreams: 1 Rogério Jorge Barbosa de Oliveira.pdf: 167540 bytes, checksum: d50995c35ae00f50bcfd54a8af8e854a (MD5)Made available in DSpace on 2015-05-04T15:36:58Z (GMT). No. of bitstreams: 1 Rogério Jorge Barbosa de Oliveira.pdf: 167540 bytes, checksum: d50995c35ae00f50bcfd54a8af8e854a (MD5) Previous issue date: 2013http://dx.doi.org/10.1590/S1676-24442013000100003reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAtherosclerosisEchocardiography vascularParaoxonaseLipoproteinsCardiovascular risk in carotid disease: assessment of doppler sonography and biomarker resultsJornal Brasileiro de Patologia e Medicina Laboratorialinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBrasilinfo:eu-repo/semantics/openAccessengORIGINALRogério Jorge Barbosa de Oliveira.pdfRogério Jorge Barbosa de Oliveira.pdfapplication/pdf167540https://repositorio.ufba.br/bitstream/ri/17526/1/Rog%c3%a9rio%20Jorge%20Barbosa%20de%20Oliveira.pdfd50995c35ae00f50bcfd54a8af8e854aMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/17526/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTRogério Jorge Barbosa de Oliveira.pdf.txtRogério Jorge Barbosa de Oliveira.pdf.txtExtracted texttext/plain34752https://repositorio.ufba.br/bitstream/ri/17526/3/Rog%c3%a9rio%20Jorge%20Barbosa%20de%20Oliveira.pdf.txt8257809163879e3753fe0d2ee15b72fcMD53ri/175262022-07-05 14:05:18.286oai:repositorio.ufba.br:ri/17526VGVybW8gZGUgTGljZW7vv71hLCBu77+9byBleGNsdXNpdm8sIHBhcmEgbyBkZXDvv71zaXRvIG5vIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBLgoKIFBlbG8gcHJvY2Vzc28gZGUgc3VibWlzc++/vW8gZGUgZG9jdW1lbnRvcywgbyBhdXRvciBvdSBzZXUgcmVwcmVzZW50YW50ZSBsZWdhbCwgYW8gYWNlaXRhciAKZXNzZSB0ZXJtbyBkZSBsaWNlbu+/vWEsIGNvbmNlZGUgYW8gUmVwb3NpdO+/vXJpbyBJbnN0aXR1Y2lvbmFsIGRhIFVuaXZlcnNpZGFkZSBGZWRlcmFsIGRhIEJhaGlhIApvIGRpcmVpdG8gZGUgbWFudGVyIHVtYSBj77+9cGlhIGVtIHNldSByZXBvc2l077+9cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCBkZSBwcmVzZXJ2Ye+/ve+/vW8uIApFc3NlcyB0ZXJtb3MsIG7vv71vIGV4Y2x1c2l2b3MsIG1hbnTvv71tIG9zIGRpcmVpdG9zIGRlIGF1dG9yL2NvcHlyaWdodCwgbWFzIGVudGVuZGUgbyBkb2N1bWVudG8gCmNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsIGRlc3NhIFVuaXZlcnNpZGFkZS4KCiBQYXJhIG9zIGRvY3VtZW50b3MgcHVibGljYWRvcyBjb20gcmVwYXNzZSBkZSBkaXJlaXRvcyBkZSBkaXN0cmlidWnvv73vv71vLCBlc3NlIHRlcm1vIGRlIGxpY2Vu77+9YSAKZW50ZW5kZSBxdWU6CgogTWFudGVuZG8gb3MgZGlyZWl0b3MgYXV0b3JhaXMsIHJlcGFzc2Fkb3MgYSB0ZXJjZWlyb3MsIGVtIGNhc28gZGUgcHVibGljYe+/ve+/vWVzLCBvIHJlcG9zaXTvv71yaW8KcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIGludGVncmFsLCBtYXMgbGliZXJhIGFzIGluZm9ybWHvv73vv71lcyBzb2JyZSBvIGRvY3VtZW50bwooTWV0YWRhZG9zIGVzY3JpdGl2b3MpLgoKIERlc3RhIGZvcm1hLCBhdGVuZGVuZG8gYW9zIGFuc2Vpb3MgZGVzc2EgdW5pdmVyc2lkYWRlIGVtIG1hbnRlciBzdWEgcHJvZHXvv73vv71vIGNpZW5077+9ZmljYSBjb20gCmFzIHJlc3Ryae+/ve+/vWVzIGltcG9zdGFzIHBlbG9zIGVkaXRvcmVzIGRlIHBlcmnvv71kaWNvcy4KCiBQYXJhIGFzIHB1YmxpY2Hvv73vv71lcyBzZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbO+/vXRpY2EgZGUgQWNlc3NvIEFiZXJ0bywgb3MgZGVw77+9c2l0b3MgCmNvbXB1bHPvv71yaW9zIG5lc3NlIHJlcG9zaXTvv71yaW8gbWFudO+/vW0gb3MgZGlyZWl0b3MgYXV0b3JhaXMsIG1hcyBtYW5077+9bSBhY2Vzc28gaXJyZXN0cml0byAKYW8gbWV0YWRhZG9zIGUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0Ye+/ve+/vW8gZGVzc2UgdGVybW8gbu+/vW8gbmVjZXNzaXRhIGRlIGNvbnNlbnRpbWVudG8KIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgZXN0YXJlbSBlbSBpbmljaWF0aXZhcyBkZSBhY2Vzc28gYWJlcnRvLgo=Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:05:18Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results
dc.title.alternative.pt_BR.fl_str_mv Jornal Brasileiro de Patologia e Medicina Laboratorial
title Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results
spellingShingle Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results
Oliveira, Rogério Jorge Barbosa de
Atherosclerosis
Echocardiography vascular
Paraoxonase
Lipoproteins
title_short Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results
title_full Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results
title_fullStr Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results
title_full_unstemmed Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results
title_sort Cardiovascular risk in carotid disease: assessment of doppler sonography and biomarker results
author Oliveira, Rogério Jorge Barbosa de
author_facet Oliveira, Rogério Jorge Barbosa de
Santos, Ana Paula Caires dos
Santos Junior, Lázaro Silveira
Vieira, Marcos Soares
Aras Júnior, Roque
Couto, Fábio David
Couto, Ricardo David
author_role author
author2 Santos, Ana Paula Caires dos
Santos Junior, Lázaro Silveira
Vieira, Marcos Soares
Aras Júnior, Roque
Couto, Fábio David
Couto, Ricardo David
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Rogério Jorge Barbosa de
Santos, Ana Paula Caires dos
Santos Junior, Lázaro Silveira
Vieira, Marcos Soares
Aras Júnior, Roque
Couto, Fábio David
Couto, Ricardo David
Oliveira, Rogério Jorge Barbosa de
Santos, Ana Paula Caires dos
Santos Junior, Lázaro Silveira
Vieira, Marcos Soares
Aras Júnior, Roque
Couto, Fábio David
Couto, Ricardo David
dc.subject.por.fl_str_mv Atherosclerosis
Echocardiography vascular
Paraoxonase
Lipoproteins
topic Atherosclerosis
Echocardiography vascular
Paraoxonase
Lipoproteins
description p.18-24
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2015-05-04T15:36:58Z
dc.date.available.fl_str_mv 2015-05-04T15:36:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/17526
dc.identifier.issn.none.fl_str_mv 1676-2444
dc.identifier.number.pt_BR.fl_str_mv v. 49, n. 1
identifier_str_mv 1676-2444
v. 49, n. 1
url http://repositorio.ufba.br/ri/handle/ri/17526
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.country.fl_str_mv Brasil
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S1676-24442013000100003
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instname_str Universidade Federal da Bahia (UFBA)
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reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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