Circulation of 3 lineages of a novel saffold cardiovirus in humans

Detalhes bibliográficos
Autor(a) principal: Drexler, Jan Felix
Data de Publicação: 2008
Outros Autores: Luna, Luciano Kleber de Souza, Stöcker, Andreas, Almeida, Patrícia Silva, Ribeiro, Tereza Cristina Medrado, Pedroso, Célia, Ribeiro, Hugo da Costa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13887
Resumo: p. 1398-1405
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spelling Drexler, Jan FelixLuna, Luciano Kleber de SouzaStöcker, AndreasAlmeida, Patrícia SilvaRibeiro, Tereza Cristina MedradoPedroso, CéliaRibeiro, Hugo da Costa2013-11-26T12:55:15Z2013-11-26T12:55:15Z20081080-6040http://repositorio.ufba.br/ri/handle/ri/13887v. 14, n. 9p. 1398-1405Cardioviruses cause serious disease, mainly in rodents, including diabetes, myocarditis, encephalomyelitis, and multiple sclerosis–like disseminated encephalomyelitis. Recently, a human virus isolate obtained 25 years ago, termed Saffold virus, was sequenced and classified as a cardiovirus. We conducted systematic molecular screening for Saffold-like viruses in 844 fecal samples from patients with gastroenteritis from Germany and Brazil, across all age groups. Six cardioviruses were identified in patients <6 years of age. Viral loads were 283,305–5,044,412,175 copies/g of stool. Co-infections occurred in 4 of 6 children. No evidence for outbreak-like epidemic patterns was found. Phylogenetic analysis identified 3 distinct genetic lineages. Viral protein 1 amino acids were 67.9%–77.7% identical and had a distance of at least 39.4% from known cardioviruses. Because closely related strains were found on 2 continents, global distribution in humans is suspected. Saffold-like viruses may be the first human cardiovirus species to be identified.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-11-26T12:26:55Z No. of bitstreams: 1 10.3201eid1409.080570.pdf: 257095 bytes, checksum: 07bdb0bfc4640ec20260e7bbfa35dcf9 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-26T12:55:15Z (GMT) No. of bitstreams: 1 10.3201eid1409.080570.pdf: 257095 bytes, checksum: 07bdb0bfc4640ec20260e7bbfa35dcf9 (MD5)Made available in DSpace on 2013-11-26T12:55:15Z (GMT). No. of bitstreams: 1 10.3201eid1409.080570.pdf: 257095 bytes, checksum: 07bdb0bfc4640ec20260e7bbfa35dcf9 (MD5) Previous issue date: 2008http://dx.doi.org/10.3201/eid1409.080570reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBACirculation of 3 lineages of a novel saffold cardiovirus in humansEmerging Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBrasilinfo:eu-repo/semantics/openAccessengORIGINAL10.3201eid1409.080570.pdf10.3201eid1409.080570.pdfapplication/pdf257095https://repositorio.ufba.br/bitstream/ri/13887/1/10.3201eid1409.080570.pdf07bdb0bfc4640ec20260e7bbfa35dcf9MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/13887/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT10.3201eid1409.080570.pdf.txt10.3201eid1409.080570.pdf.txtExtracted texttext/plain42713https://repositorio.ufba.br/bitstream/ri/13887/3/10.3201eid1409.080570.pdf.txtc09d05f4731b062f4c378d4c84f57723MD53ri/138872022-03-10 13:51:59.917oai:repositorio.ufba.br:ri/13887VGVybW8gZGUgTGljZW7vv71hLCBu77+9byBleGNsdXNpdm8sIHBhcmEgbyBkZXDvv71zaXRvIG5vIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBLgoKIFBlbG8gcHJvY2Vzc28gZGUgc3VibWlzc++/vW8gZGUgZG9jdW1lbnRvcywgbyBhdXRvciBvdSBzZXUgcmVwcmVzZW50YW50ZSBsZWdhbCwgYW8gYWNlaXRhciAKZXNzZSB0ZXJtbyBkZSBsaWNlbu+/vWEsIGNvbmNlZGUgYW8gUmVwb3NpdO+/vXJpbyBJbnN0aXR1Y2lvbmFsIGRhIFVuaXZlcnNpZGFkZSBGZWRlcmFsIGRhIEJhaGlhIApvIGRpcmVpdG8gZGUgbWFudGVyIHVtYSBj77+9cGlhIGVtIHNldSByZXBvc2l077+9cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCBkZSBwcmVzZXJ2Ye+/ve+/vW8uIApFc3NlcyB0ZXJtb3MsIG7vv71vIGV4Y2x1c2l2b3MsIG1hbnTvv71tIG9zIGRpcmVpdG9zIGRlIGF1dG9yL2NvcHlyaWdodCwgbWFzIGVudGVuZGUgbyBkb2N1bWVudG8gCmNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsIGRlc3NhIFVuaXZlcnNpZGFkZS4KCiBQYXJhIG9zIGRvY3VtZW50b3MgcHVibGljYWRvcyBjb20gcmVwYXNzZSBkZSBkaXJlaXRvcyBkZSBkaXN0cmlidWnvv73vv71vLCBlc3NlIHRlcm1vIGRlIGxpY2Vu77+9YSAKZW50ZW5kZSBxdWU6CgogTWFudGVuZG8gb3MgZGlyZWl0b3MgYXV0b3JhaXMsIHJlcGFzc2Fkb3MgYSB0ZXJjZWlyb3MsIGVtIGNhc28gZGUgcHVibGljYe+/ve+/vWVzLCBvIHJlcG9zaXTvv71yaW8KcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIGludGVncmFsLCBtYXMgbGliZXJhIGFzIGluZm9ybWHvv73vv71lcyBzb2JyZSBvIGRvY3VtZW50bwooTWV0YWRhZG9zIGVzY3JpdGl2b3MpLgoKIERlc3RhIGZvcm1hLCBhdGVuZGVuZG8gYW9zIGFuc2Vpb3MgZGVzc2EgdW5pdmVyc2lkYWRlIGVtIG1hbnRlciBzdWEgcHJvZHXvv73vv71vIGNpZW5077+9ZmljYSBjb20gCmFzIHJlc3Ryae+/ve+/vWVzIGltcG9zdGFzIHBlbG9zIGVkaXRvcmVzIGRlIHBlcmnvv71kaWNvcy4KCiBQYXJhIGFzIHB1YmxpY2Hvv73vv71lcyBzZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbO+/vXRpY2EgZGUgQWNlc3NvIEFiZXJ0bywgb3MgZGVw77+9c2l0b3MgCmNvbXB1bHPvv71yaW9zIG5lc3NlIHJlcG9zaXTvv71yaW8gbWFudO+/vW0gb3MgZGlyZWl0b3MgYXV0b3JhaXMsIG1hcyBtYW5077+9bSBhY2Vzc28gaXJyZXN0cml0byAKYW8gbWV0YWRhZG9zIGUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0Ye+/ve+/vW8gZGVzc2UgdGVybW8gbu+/vW8gbmVjZXNzaXRhIGRlIGNvbnNlbnRpbWVudG8KIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgZXN0YXJlbSBlbSBpbmljaWF0aXZhcyBkZSBhY2Vzc28gYWJlcnRvLgo=Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-03-10T16:51:59Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Circulation of 3 lineages of a novel saffold cardiovirus in humans
dc.title.alternative.pt_BR.fl_str_mv Emerging Infectious Diseases
title Circulation of 3 lineages of a novel saffold cardiovirus in humans
spellingShingle Circulation of 3 lineages of a novel saffold cardiovirus in humans
Drexler, Jan Felix
title_short Circulation of 3 lineages of a novel saffold cardiovirus in humans
title_full Circulation of 3 lineages of a novel saffold cardiovirus in humans
title_fullStr Circulation of 3 lineages of a novel saffold cardiovirus in humans
title_full_unstemmed Circulation of 3 lineages of a novel saffold cardiovirus in humans
title_sort Circulation of 3 lineages of a novel saffold cardiovirus in humans
author Drexler, Jan Felix
author_facet Drexler, Jan Felix
Luna, Luciano Kleber de Souza
Stöcker, Andreas
Almeida, Patrícia Silva
Ribeiro, Tereza Cristina Medrado
Pedroso, Célia
Ribeiro, Hugo da Costa
author_role author
author2 Luna, Luciano Kleber de Souza
Stöcker, Andreas
Almeida, Patrícia Silva
Ribeiro, Tereza Cristina Medrado
Pedroso, Célia
Ribeiro, Hugo da Costa
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Drexler, Jan Felix
Luna, Luciano Kleber de Souza
Stöcker, Andreas
Almeida, Patrícia Silva
Ribeiro, Tereza Cristina Medrado
Pedroso, Célia
Ribeiro, Hugo da Costa
description p. 1398-1405
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2013-11-26T12:55:15Z
dc.date.available.fl_str_mv 2013-11-26T12:55:15Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13887
dc.identifier.issn.none.fl_str_mv 1080-6040
dc.identifier.number.pt_BR.fl_str_mv v. 14, n. 9
identifier_str_mv 1080-6040
v. 14, n. 9
url http://repositorio.ufba.br/ri/handle/ri/13887
dc.language.iso.fl_str_mv eng
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.country.fl_str_mv Brasil
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