Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity

Detalhes bibliográficos
Autor(a) principal: Cruz, Andréa Cristina Santos da
Data de Publicação: 2012
Outros Autores: Leite, Maria Bernadete Neiva Lemos, Rodrigues, Luiz Erlon Araújo, Nascimento, Iracema Andrade
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/17078
Resumo: Texto completo: acesso restrito. p.219-224
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spelling Cruz, Andréa Cristina Santos daLeite, Maria Bernadete Neiva LemosRodrigues, Luiz Erlon AraújoNascimento, Iracema AndradeCruz, Andréa Cristina Santos daLeite, Maria Bernadete Neiva LemosRodrigues, Luiz Erlon AraújoNascimento, Iracema Andrade2015-03-03T14:15:24Z20120007-4861http://repositorio.ufba.br/ri/handle/ri/17078v. 89, n. 2Texto completo: acesso restrito. p.219-224Biodiesel is promoted as environmentally less harmful than diesel fuel. Nevertheless its water-soluble-fraction (WSF) may contain methanol, which appears by a reversion of the transesterification reaction, when biodiesel contacts water. This paper evaluated the loss of the lysosomal membrane integrity in liver homogenate of juvenils Tilapia exposed to biodiesels-WSF, through the increase of the acid phosphatase activity, as an evidence of citotoxicity. Differences in the enzyme activity levels (3.4, 2.3 and 0.8 mU mg−1 total protein over the control value, which was 1.6 mU mg−1 total protein), found for castor oil, waste cooking-oil and palm oil-biodiesels, respectively, were indicative of their toxicity according to this decreasing trend. WSF-chromatograms suggest the cytotoxicity as related to methanol.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2015-03-03T11:57:00Z No. of bitstreams: 1 7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf: 3368148 bytes, checksum: b590132114f87c03d23b57ca1c03b1ae (MD5)Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2015-03-03T14:15:24Z (GMT) No. of bitstreams: 1 7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf: 3368148 bytes, checksum: b590132114f87c03d23b57ca1c03b1ae (MD5)Made available in DSpace on 2015-03-03T14:15:24Z (GMT). No. of bitstreams: 1 7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf: 3368148 bytes, checksum: b590132114f87c03d23b57ca1c03b1ae (MD5) Previous issue date: 2012http://dx.doi.org/10.1007/s00128-012-0707-7reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBABiodieselHepatotoxicityLysosomal biomarkerAcid phosphataseEstimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal IntegrityBulletin of Environmental Contamination and Toxicologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdfapplication/pdf3368148https://repositorio.ufba.br/bitstream/ri/17078/1/7-Bull%20Environ%20Contam%20Toxicol%2089%20p.%202019-2024%2c%202012.pdfb590132114f87c03d23b57ca1c03b1aeMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/17078/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf.txt7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf.txtExtracted texttext/plain6https://repositorio.ufba.br/bitstream/ri/17078/3/7-Bull%20Environ%20Contam%20Toxicol%2089%20p.%202019-2024%2c%202012.pdf.txt6d93d3216dc4a7f5df47d4876fbec4d3MD53ri/170782022-07-05 14:02:49.008oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:49Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
dc.title.alternative.pt_BR.fl_str_mv Bulletin of Environmental Contamination and Toxicology
title Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
spellingShingle Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
Cruz, Andréa Cristina Santos da
Biodiesel
Hepatotoxicity
Lysosomal biomarker
Acid phosphatase
title_short Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
title_full Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
title_fullStr Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
title_full_unstemmed Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
title_sort Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
author Cruz, Andréa Cristina Santos da
author_facet Cruz, Andréa Cristina Santos da
Leite, Maria Bernadete Neiva Lemos
Rodrigues, Luiz Erlon Araújo
Nascimento, Iracema Andrade
author_role author
author2 Leite, Maria Bernadete Neiva Lemos
Rodrigues, Luiz Erlon Araújo
Nascimento, Iracema Andrade
author2_role author
author
author
dc.contributor.author.fl_str_mv Cruz, Andréa Cristina Santos da
Leite, Maria Bernadete Neiva Lemos
Rodrigues, Luiz Erlon Araújo
Nascimento, Iracema Andrade
Cruz, Andréa Cristina Santos da
Leite, Maria Bernadete Neiva Lemos
Rodrigues, Luiz Erlon Araújo
Nascimento, Iracema Andrade
dc.subject.por.fl_str_mv Biodiesel
Hepatotoxicity
Lysosomal biomarker
Acid phosphatase
topic Biodiesel
Hepatotoxicity
Lysosomal biomarker
Acid phosphatase
description Texto completo: acesso restrito. p.219-224
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2015-03-03T14:15:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/17078
dc.identifier.issn.none.fl_str_mv 0007-4861
dc.identifier.number.pt_BR.fl_str_mv v. 89, n. 2
identifier_str_mv 0007-4861
v. 89, n. 2
url http://repositorio.ufba.br/ri/handle/ri/17078
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1007/s00128-012-0707-7
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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