Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/17078 |
Resumo: | Texto completo: acesso restrito. p.219-224 |
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Cruz, Andréa Cristina Santos daLeite, Maria Bernadete Neiva LemosRodrigues, Luiz Erlon AraújoNascimento, Iracema AndradeCruz, Andréa Cristina Santos daLeite, Maria Bernadete Neiva LemosRodrigues, Luiz Erlon AraújoNascimento, Iracema Andrade2015-03-03T14:15:24Z20120007-4861http://repositorio.ufba.br/ri/handle/ri/17078v. 89, n. 2Texto completo: acesso restrito. p.219-224Biodiesel is promoted as environmentally less harmful than diesel fuel. Nevertheless its water-soluble-fraction (WSF) may contain methanol, which appears by a reversion of the transesterification reaction, when biodiesel contacts water. This paper evaluated the loss of the lysosomal membrane integrity in liver homogenate of juvenils Tilapia exposed to biodiesels-WSF, through the increase of the acid phosphatase activity, as an evidence of citotoxicity. Differences in the enzyme activity levels (3.4, 2.3 and 0.8 mU mg−1 total protein over the control value, which was 1.6 mU mg−1 total protein), found for castor oil, waste cooking-oil and palm oil-biodiesels, respectively, were indicative of their toxicity according to this decreasing trend. WSF-chromatograms suggest the cytotoxicity as related to methanol.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2015-03-03T11:57:00Z No. of bitstreams: 1 7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf: 3368148 bytes, checksum: b590132114f87c03d23b57ca1c03b1ae (MD5)Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2015-03-03T14:15:24Z (GMT) No. of bitstreams: 1 7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf: 3368148 bytes, checksum: b590132114f87c03d23b57ca1c03b1ae (MD5)Made available in DSpace on 2015-03-03T14:15:24Z (GMT). No. of bitstreams: 1 7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf: 3368148 bytes, checksum: b590132114f87c03d23b57ca1c03b1ae (MD5) Previous issue date: 2012http://dx.doi.org/10.1007/s00128-012-0707-7reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBABiodieselHepatotoxicityLysosomal biomarkerAcid phosphataseEstimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal IntegrityBulletin of Environmental Contamination and Toxicologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdfapplication/pdf3368148https://repositorio.ufba.br/bitstream/ri/17078/1/7-Bull%20Environ%20Contam%20Toxicol%2089%20p.%202019-2024%2c%202012.pdfb590132114f87c03d23b57ca1c03b1aeMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/17078/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf.txt7-Bull Environ Contam Toxicol 89 p. 2019-2024, 2012.pdf.txtExtracted texttext/plain6https://repositorio.ufba.br/bitstream/ri/17078/3/7-Bull%20Environ%20Contam%20Toxicol%2089%20p.%202019-2024%2c%202012.pdf.txt6d93d3216dc4a7f5df47d4876fbec4d3MD53ri/170782022-07-05 14:02:49.008oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:49Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity |
dc.title.alternative.pt_BR.fl_str_mv |
Bulletin of Environmental Contamination and Toxicology |
title |
Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity |
spellingShingle |
Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity Cruz, Andréa Cristina Santos da Biodiesel Hepatotoxicity Lysosomal biomarker Acid phosphatase |
title_short |
Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity |
title_full |
Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity |
title_fullStr |
Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity |
title_full_unstemmed |
Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity |
title_sort |
Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity |
author |
Cruz, Andréa Cristina Santos da |
author_facet |
Cruz, Andréa Cristina Santos da Leite, Maria Bernadete Neiva Lemos Rodrigues, Luiz Erlon Araújo Nascimento, Iracema Andrade |
author_role |
author |
author2 |
Leite, Maria Bernadete Neiva Lemos Rodrigues, Luiz Erlon Araújo Nascimento, Iracema Andrade |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Cruz, Andréa Cristina Santos da Leite, Maria Bernadete Neiva Lemos Rodrigues, Luiz Erlon Araújo Nascimento, Iracema Andrade Cruz, Andréa Cristina Santos da Leite, Maria Bernadete Neiva Lemos Rodrigues, Luiz Erlon Araújo Nascimento, Iracema Andrade |
dc.subject.por.fl_str_mv |
Biodiesel Hepatotoxicity Lysosomal biomarker Acid phosphatase |
topic |
Biodiesel Hepatotoxicity Lysosomal biomarker Acid phosphatase |
description |
Texto completo: acesso restrito. p.219-224 |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2015-03-03T14:15:24Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufba.br/ri/handle/ri/17078 |
dc.identifier.issn.none.fl_str_mv |
0007-4861 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 89, n. 2 |
identifier_str_mv |
0007-4861 v. 89, n. 2 |
url |
http://repositorio.ufba.br/ri/handle/ri/17078 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/10.1007/s00128-012-0707-7 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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