Genetic risk factors for human susceptibility to infections of relevance in dermatology
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/6532 |
Resumo: | p.708-715 |
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Sardinha, José Felipe JardimTarlé, Roberto GomesFava, Vinícius MedeirosFrancio, Angela SchneiderRamos, Geovana BrottoFerreira, Luiz Carlos de LimaSchriefer, Nicolaus Albert BorgesMira, Marcelo TávoraTalhari, SinésioSardinha, José Felipe JardimTarlé, Roberto GomesFava, Vinícius MedeirosFrancio, Angela SchneiderRamos, Geovana BrottoFerreira, Luiz Carlos de LimaSchriefer, Nicolaus Albert BorgesMira, Marcelo TávoraTalhari, Sinésio2012-08-03T16:59:17Z2012-08-03T16:59:17Z2011-010365-0596http://www.repositorio.ufba.br/ri/handle/ri/6532v. 86, n. 4p.708-715BACKGROUND: In the pre-microbiological era, it was widely accepted that diseases, today known to be infectious, were hereditary. With the discovery of microorganisms and their role in the pathogenesis of several diseases, it was suggested that exposure to the pathogen was enough to explain infection. Nowadays, it is clear that infection is the result of a complex interplay between pathogen and host, therefore dependant on the genetic make-up of the two organisms. Dermatology offers several examples of infectious diseases in different stages of understanding of their molecular basis. In this review, we summarize the main advances towards dissecting the genetic component controlling human susceptibility to infectious diseases of interest in dermatology. Widely investigated diseases such as leprosy and leishmaniasis are discussed from the genetic perspective of both host and pathogen. Others, such as rare mycobacterioses, fungal infections and syphilis, are presented as good opportunities for research in the field of genetics of infection.Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-08-03T16:59:17Z No. of bitstreams: 1 Sardinha, José Felipe Jardim.pdf: 132084 bytes, checksum: 035d899f6558e1e920f5e0185caaf0c5 (MD5)Made available in DSpace on 2012-08-03T16:59:17Z (GMT). No. of bitstreams: 1 Sardinha, José Felipe Jardim.pdf: 132084 bytes, checksum: 035d899f6558e1e920f5e0185caaf0c5 (MD5) Previous issue date: 2011-01Rio de JaneiroSociedade Brasileira de Dermatologiahttp://dx.doi.org/10.1590/S0365-05962011000400013reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBADermatologyInfectionPolymorphismGeneticGenetic risk factors for human susceptibility to infections of relevance in dermatologyAnais Brasileiros de Dermatologiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINALSardinha, José Felipe Jardim.pdfSardinha, José Felipe Jardim.pdfapplication/pdf132084https://repositorio.ufba.br/bitstream/ri/6532/1/Sardinha%2c%20Jos%c3%a9%20Felipe%20Jardim.pdf035d899f6558e1e920f5e0185caaf0c5MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6532/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTSardinha, José Felipe Jardim.pdf.txtSardinha, José Felipe Jardim.pdf.txtExtracted texttext/plain51554https://repositorio.ufba.br/bitstream/ri/6532/3/Sardinha%2c%20Jos%c3%a9%20Felipe%20Jardim.pdf.txte5f9b00afd42c5ecea836eed7fbade22MD53ri/65322022-07-05 14:03:22.409oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:22Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Genetic risk factors for human susceptibility to infections of relevance in dermatology |
dc.title.alternative.pt_BR.fl_str_mv |
Anais Brasileiros de Dermatologia |
title |
Genetic risk factors for human susceptibility to infections of relevance in dermatology |
spellingShingle |
Genetic risk factors for human susceptibility to infections of relevance in dermatology Sardinha, José Felipe Jardim Dermatology Infection Polymorphism Genetic |
title_short |
Genetic risk factors for human susceptibility to infections of relevance in dermatology |
title_full |
Genetic risk factors for human susceptibility to infections of relevance in dermatology |
title_fullStr |
Genetic risk factors for human susceptibility to infections of relevance in dermatology |
title_full_unstemmed |
Genetic risk factors for human susceptibility to infections of relevance in dermatology |
title_sort |
Genetic risk factors for human susceptibility to infections of relevance in dermatology |
author |
Sardinha, José Felipe Jardim |
author_facet |
Sardinha, José Felipe Jardim Tarlé, Roberto Gomes Fava, Vinícius Medeiros Francio, Angela Schneider Ramos, Geovana Brotto Ferreira, Luiz Carlos de Lima Schriefer, Nicolaus Albert Borges Mira, Marcelo Távora Talhari, Sinésio |
author_role |
author |
author2 |
Tarlé, Roberto Gomes Fava, Vinícius Medeiros Francio, Angela Schneider Ramos, Geovana Brotto Ferreira, Luiz Carlos de Lima Schriefer, Nicolaus Albert Borges Mira, Marcelo Távora Talhari, Sinésio |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Sardinha, José Felipe Jardim Tarlé, Roberto Gomes Fava, Vinícius Medeiros Francio, Angela Schneider Ramos, Geovana Brotto Ferreira, Luiz Carlos de Lima Schriefer, Nicolaus Albert Borges Mira, Marcelo Távora Talhari, Sinésio Sardinha, José Felipe Jardim Tarlé, Roberto Gomes Fava, Vinícius Medeiros Francio, Angela Schneider Ramos, Geovana Brotto Ferreira, Luiz Carlos de Lima Schriefer, Nicolaus Albert Borges Mira, Marcelo Távora Talhari, Sinésio |
dc.subject.por.fl_str_mv |
Dermatology Infection Polymorphism Genetic |
topic |
Dermatology Infection Polymorphism Genetic |
description |
p.708-715 |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011-01 |
dc.date.accessioned.fl_str_mv |
2012-08-03T16:59:17Z |
dc.date.available.fl_str_mv |
2012-08-03T16:59:17Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/6532 |
dc.identifier.issn.none.fl_str_mv |
0365-0596 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 86, n. 4 |
identifier_str_mv |
0365-0596 v. 86, n. 4 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/6532 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/10.1590/S0365-05962011000400013 |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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