Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
Autor(a) principal: | |
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Data de Publicação: | 1988 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/8380 |
Resumo: | p. 283-287 |
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Salvadori, D. M. F.Ribeiro, L. R.Pereira, Carlos Alberto BraganfaBeçak, WillySalvadori, D. M. F.Ribeiro, L. R.Pereira, Carlos Alberto BraganfaBeçak, Willy2013-02-05T20:56:03Z2013-02-05T20:56:03Z1988http://www.repositorio.ufba.br/ri/handle/ri/8380v. 204, n. 2p. 283-287Male mice dermally exposed to single or multiple treatment (5 days/2 weeks) showed that the ability of malathion to induce chromosome aberrations in somatic (bone marrow) and germ cells (primary spermatocytes) was related to the type of treatment and dose used. Statistically significant increases of chromosome aberrations in bone marrow cells occurred after single treatment (500 and 2000 mg/kg body wt) when chromatid gaps were included and after multiple treatment (250 and 500 mg/kg) when they were excluded. No dose—response relationships were observed for either treatment. In germ cells, malathion induced a significant increase of univalents in both types of treatment but structural chromosome aberrations were induced only by multiple treatment. Malathion induced a significant decrease of the mitotic indices in the bone marrow.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-02-04T20:22:53Z No. of bitstreams: 1 7777777777777777.pdf: 321334 bytes, checksum: a1f512ad323e73443c613ab48b6d546f (MD5)Approved for entry into archive by Alda Lima da Silva(sivalda@ufba.br) on 2013-02-05T20:56:03Z (GMT) No. of bitstreams: 1 7777777777777777.pdf: 321334 bytes, checksum: a1f512ad323e73443c613ab48b6d546f (MD5)Made available in DSpace on 2013-02-05T20:56:03Z (GMT). No. of bitstreams: 1 7777777777777777.pdf: 321334 bytes, checksum: a1f512ad323e73443c613ab48b6d546f (MD5) Previous issue date: 1988SalvadorMutation Research/Genetic Toxicologyhttp://dx.doi.org/10.1016/0165-1218(88)90101-2reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAMalathionChromosome aberrationMouseAbnormalitiesCytogenetic effects of malathion insecticide on somatic and germ cells of miceMutation Research/Genetic Toxicologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL7777777777777777.pdf7777777777777777.pdfapplication/pdf321334https://repositorio.ufba.br/bitstream/ri/8380/1/7777777777777777.pdfa1f512ad323e73443c613ab48b6d546fMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/8380/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT7777777777777777.pdf.txt7777777777777777.pdf.txtExtracted texttext/plain14244https://repositorio.ufba.br/bitstream/ri/8380/3/7777777777777777.pdf.txt1f9b7a9f1627455bc19953ebcdc927eaMD53ri/83802022-07-05 14:04:14.302oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:04:14Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Cytogenetic effects of malathion insecticide on somatic and germ cells of mice |
dc.title.alternative.pt_BR.fl_str_mv |
Mutation Research/Genetic Toxicology |
title |
Cytogenetic effects of malathion insecticide on somatic and germ cells of mice |
spellingShingle |
Cytogenetic effects of malathion insecticide on somatic and germ cells of mice Salvadori, D. M. F. Malathion Chromosome aberration Mouse Abnormalities |
title_short |
Cytogenetic effects of malathion insecticide on somatic and germ cells of mice |
title_full |
Cytogenetic effects of malathion insecticide on somatic and germ cells of mice |
title_fullStr |
Cytogenetic effects of malathion insecticide on somatic and germ cells of mice |
title_full_unstemmed |
Cytogenetic effects of malathion insecticide on somatic and germ cells of mice |
title_sort |
Cytogenetic effects of malathion insecticide on somatic and germ cells of mice |
author |
Salvadori, D. M. F. |
author_facet |
Salvadori, D. M. F. Ribeiro, L. R. Pereira, Carlos Alberto Braganfa Beçak, Willy |
author_role |
author |
author2 |
Ribeiro, L. R. Pereira, Carlos Alberto Braganfa Beçak, Willy |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Salvadori, D. M. F. Ribeiro, L. R. Pereira, Carlos Alberto Braganfa Beçak, Willy Salvadori, D. M. F. Ribeiro, L. R. Pereira, Carlos Alberto Braganfa Beçak, Willy |
dc.subject.por.fl_str_mv |
Malathion Chromosome aberration Mouse Abnormalities |
topic |
Malathion Chromosome aberration Mouse Abnormalities |
description |
p. 283-287 |
publishDate |
1988 |
dc.date.issued.fl_str_mv |
1988 |
dc.date.accessioned.fl_str_mv |
2013-02-05T20:56:03Z |
dc.date.available.fl_str_mv |
2013-02-05T20:56:03Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/8380 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 204, n. 2 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/8380 |
identifier_str_mv |
v. 204, n. 2 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Mutation Research/Genetic Toxicology |
publisher.none.fl_str_mv |
Mutation Research/Genetic Toxicology |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/10.1016/0165-1218(88)90101-2 |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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