Cytogenetic effects of malathion insecticide on somatic and germ cells of mice

Detalhes bibliográficos
Autor(a) principal: Salvadori, D. M. F.
Data de Publicação: 1988
Outros Autores: Ribeiro, L. R., Pereira, Carlos Alberto Braganfa, Beçak, Willy
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/8380
Resumo: p. 283-287
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spelling Salvadori, D. M. F.Ribeiro, L. R.Pereira, Carlos Alberto BraganfaBeçak, WillySalvadori, D. M. F.Ribeiro, L. R.Pereira, Carlos Alberto BraganfaBeçak, Willy2013-02-05T20:56:03Z2013-02-05T20:56:03Z1988http://www.repositorio.ufba.br/ri/handle/ri/8380v. 204, n. 2p. 283-287Male mice dermally exposed to single or multiple treatment (5 days/2 weeks) showed that the ability of malathion to induce chromosome aberrations in somatic (bone marrow) and germ cells (primary spermatocytes) was related to the type of treatment and dose used. Statistically significant increases of chromosome aberrations in bone marrow cells occurred after single treatment (500 and 2000 mg/kg body wt) when chromatid gaps were included and after multiple treatment (250 and 500 mg/kg) when they were excluded. No dose—response relationships were observed for either treatment. In germ cells, malathion induced a significant increase of univalents in both types of treatment but structural chromosome aberrations were induced only by multiple treatment. Malathion induced a significant decrease of the mitotic indices in the bone marrow.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-02-04T20:22:53Z No. of bitstreams: 1 7777777777777777.pdf: 321334 bytes, checksum: a1f512ad323e73443c613ab48b6d546f (MD5)Approved for entry into archive by Alda Lima da Silva(sivalda@ufba.br) on 2013-02-05T20:56:03Z (GMT) No. of bitstreams: 1 7777777777777777.pdf: 321334 bytes, checksum: a1f512ad323e73443c613ab48b6d546f (MD5)Made available in DSpace on 2013-02-05T20:56:03Z (GMT). No. of bitstreams: 1 7777777777777777.pdf: 321334 bytes, checksum: a1f512ad323e73443c613ab48b6d546f (MD5) Previous issue date: 1988SalvadorMutation Research/Genetic Toxicologyhttp://dx.doi.org/10.1016/0165-1218(88)90101-2reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAMalathionChromosome aberrationMouseAbnormalitiesCytogenetic effects of malathion insecticide on somatic and germ cells of miceMutation Research/Genetic Toxicologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL7777777777777777.pdf7777777777777777.pdfapplication/pdf321334https://repositorio.ufba.br/bitstream/ri/8380/1/7777777777777777.pdfa1f512ad323e73443c613ab48b6d546fMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/8380/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT7777777777777777.pdf.txt7777777777777777.pdf.txtExtracted texttext/plain14244https://repositorio.ufba.br/bitstream/ri/8380/3/7777777777777777.pdf.txt1f9b7a9f1627455bc19953ebcdc927eaMD53ri/83802022-07-05 14:04:14.302oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:04:14Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
dc.title.alternative.pt_BR.fl_str_mv Mutation Research/Genetic Toxicology
title Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
spellingShingle Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
Salvadori, D. M. F.
Malathion
Chromosome aberration
Mouse
Abnormalities
title_short Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
title_full Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
title_fullStr Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
title_full_unstemmed Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
title_sort Cytogenetic effects of malathion insecticide on somatic and germ cells of mice
author Salvadori, D. M. F.
author_facet Salvadori, D. M. F.
Ribeiro, L. R.
Pereira, Carlos Alberto Braganfa
Beçak, Willy
author_role author
author2 Ribeiro, L. R.
Pereira, Carlos Alberto Braganfa
Beçak, Willy
author2_role author
author
author
dc.contributor.author.fl_str_mv Salvadori, D. M. F.
Ribeiro, L. R.
Pereira, Carlos Alberto Braganfa
Beçak, Willy
Salvadori, D. M. F.
Ribeiro, L. R.
Pereira, Carlos Alberto Braganfa
Beçak, Willy
dc.subject.por.fl_str_mv Malathion
Chromosome aberration
Mouse
Abnormalities
topic Malathion
Chromosome aberration
Mouse
Abnormalities
description p. 283-287
publishDate 1988
dc.date.issued.fl_str_mv 1988
dc.date.accessioned.fl_str_mv 2013-02-05T20:56:03Z
dc.date.available.fl_str_mv 2013-02-05T20:56:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/8380
dc.identifier.number.pt_BR.fl_str_mv v. 204, n. 2
url http://www.repositorio.ufba.br/ri/handle/ri/8380
identifier_str_mv v. 204, n. 2
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Mutation Research/Genetic Toxicology
publisher.none.fl_str_mv Mutation Research/Genetic Toxicology
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/0165-1218(88)90101-2
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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