What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata

Detalhes bibliográficos
Autor(a) principal: Santos, Clarice Machado
Data de Publicação: 2013
Outros Autores: Aquino, Júlio César Fraulob, Mikalauka, Jefferson Simanas, Figueiredo, Marcelo Abidu, Mendes, Rosa Maria Marcos, Sales, Armando
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13827
Resumo: p. 62–68
id UFBA-2_aacf144210db768f7dd3b55a01837c6b
oai_identifier_str oai:repositorio.ufba.br:ri/13827
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Santos, Clarice MachadoAquino, Júlio César FraulobMikalauka, Jefferson SimanasFigueiredo, Marcelo AbiduMendes, Rosa Maria MarcosSales, ArmandoSantos, Clarice MachadoAquino, Júlio César FraulobMikalauka, Jefferson SimanasFigueiredo, Marcelo AbiduMendes, Rosa Maria MarcosSales, Armando2013-11-20T19:48:07Z20130167-0115http://repositorio.ufba.br/ri/handle/ri/13827v. 183p. 62–68Diphylla ecaudata is a vampire bat that mainly feeds on the blood of birds. This highly specialized diet - hematophagy – is accompanied by a series of morphological changes in the gastro-entero-pancreatic system, since the distribution and relative proportions of different pancreatic endocrine cell types can vary between species due to different physiological conditions and eating habits. The aim of this study was to examine for the first time the pancreas of the vampire bat D. ecaudata using morphological, stereological and immunohistochemical techniques. The pancreas of the D. ecaudata has an exocrine acinar portion in which the highest concentration of pancreatic islets is scattered. These pancreatic islets have irregular size and a mean diameter of 56.94 μm. The total number of islets in the pancreas was 23,900, with a volumetric density of 4.1%. Insulin-immunoreactive (IR) cells were located in the central pancreatic islet region and had the largest density (54.8%). Glucagon-IR cells were located mainly in the peripheral mantle region (16.2%), along with somatostatin-IR (SS) cells (14.3%). Cells immunoreactive to insulin, glucagon and somatostatin were also observed to have spread in isolated places in the exocrine pancreas. In the connective tissue near the pancreatic ducts, a high concentration was identified of insulin-IR cells and a low concentration of glucagon-IR and somatostatin-IR cells. These results indicate that although the pancreas of D. ecaudata has morphological similarities with that of other mammals, it has a differentiated islet structure, because there were a large number of islets and different volumetric densities of α, β and δ cells.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-11-13T19:11:11Z No. of bitstreams: 1 22222.pdf: 1990421 bytes, checksum: be4e9fb147275731d65ad8cfc0c5884a (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-20T19:48:06Z (GMT) No. of bitstreams: 1 22222.pdf: 1990421 bytes, checksum: be4e9fb147275731d65ad8cfc0c5884a (MD5)Made available in DSpace on 2013-11-20T19:48:07Z (GMT). No. of bitstreams: 1 22222.pdf: 1990421 bytes, checksum: be4e9fb147275731d65ad8cfc0c5884a (MD5) Previous issue date: 2013SalvadorRegulatory Peptideshttp://www.sciencedirect.com/science/article/pii/S016701151300044Xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAPancreasChiropteraEndocrine cellsHistologyWhat difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudataRegulatory Peptidesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL22222.pdf22222.pdfapplication/pdf1990421https://repositorio.ufba.br/bitstream/ri/13827/1/22222.pdfbe4e9fb147275731d65ad8cfc0c5884aMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/13827/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT22222.pdf.txt22222.pdf.txtExtracted texttext/plain37000https://repositorio.ufba.br/bitstream/ri/13827/3/22222.pdf.txt5ecc4664839a1d30d7ffba08ec229508MD53ri/138272022-07-05 14:03:42.556oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:42Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata
dc.title.alternative.pt_BR.fl_str_mv Regulatory Peptides
title What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata
spellingShingle What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata
Santos, Clarice Machado
Pancreas
Chiroptera
Endocrine cells
Histology
title_short What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata
title_full What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata
title_fullStr What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata
title_full_unstemmed What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata
title_sort What difference exists in the pancreas of mammals with sanguivorous diet? A morphological, stereological and immunohistochemical study of the pancreatic islets of the hematophagous bat Diphylla ecaudata
author Santos, Clarice Machado
author_facet Santos, Clarice Machado
Aquino, Júlio César Fraulob
Mikalauka, Jefferson Simanas
Figueiredo, Marcelo Abidu
Mendes, Rosa Maria Marcos
Sales, Armando
author_role author
author2 Aquino, Júlio César Fraulob
Mikalauka, Jefferson Simanas
Figueiredo, Marcelo Abidu
Mendes, Rosa Maria Marcos
Sales, Armando
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Santos, Clarice Machado
Aquino, Júlio César Fraulob
Mikalauka, Jefferson Simanas
Figueiredo, Marcelo Abidu
Mendes, Rosa Maria Marcos
Sales, Armando
Santos, Clarice Machado
Aquino, Júlio César Fraulob
Mikalauka, Jefferson Simanas
Figueiredo, Marcelo Abidu
Mendes, Rosa Maria Marcos
Sales, Armando
dc.subject.por.fl_str_mv Pancreas
Chiroptera
Endocrine cells
Histology
topic Pancreas
Chiroptera
Endocrine cells
Histology
description p. 62–68
publishDate 2013
dc.date.accessioned.fl_str_mv 2013-11-20T19:48:07Z
dc.date.issued.fl_str_mv 2013
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13827
dc.identifier.issn.none.fl_str_mv 0167-0115
dc.identifier.number.pt_BR.fl_str_mv v. 183
identifier_str_mv 0167-0115
v. 183
url http://repositorio.ufba.br/ri/handle/ri/13827
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Regulatory Peptides
publisher.none.fl_str_mv Regulatory Peptides
dc.source.pt_BR.fl_str_mv http://www.sciencedirect.com/science/article/pii/S016701151300044X
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/13827/1/22222.pdf
https://repositorio.ufba.br/bitstream/ri/13827/2/license.txt
https://repositorio.ufba.br/bitstream/ri/13827/3/22222.pdf.txt
bitstream.checksum.fl_str_mv be4e9fb147275731d65ad8cfc0c5884a
ff6eaa8b858ea317fded99f125f5fcd0
5ecc4664839a1d30d7ffba08ec229508
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1808459464753283072

Registros relacionados