Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate

Detalhes bibliográficos
Autor(a) principal: Coutinho, Elsimar Metzker
Data de Publicação: 2000
Outros Autores: Spinola, Paulo, Tomaz, Geraldez, Morais, Kleber, Souza, Rosival Nassar de, Pinho Neto, João Sabino, Leal, Weydson de Barros, Hippolito, Silvia Bomfim, Abranches, Anthony D'Aurea
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/7874
Resumo: Texto completo: acesso restrito. p. 277–280
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spelling Coutinho, Elsimar MetzkerSpinola, PauloTomaz, GeraldezMorais, KleberSouza, Rosival Nassar dePinho Neto, João SabinoLeal, Weydson de BarrosHippolito, Silvia BomfimAbranches, Anthony D'AureaCoutinho, Elsimar MetzkerSpinola, PauloTomaz, GeraldezMorais, KleberSouza, Rosival Nassar dePinho Neto, João SabinoLeal, Weydson de BarrosHippolito, Silvia BomfimAbranches, Anthony D'Aurea2013-01-16T11:28:26Z20000010-7824http://www.repositorio.ufba.br/ri/handle/ri/7874v. 61, n. 4Texto completo: acesso restrito. p. 277–280A total of 1,904 women, aged 15–38, used an injectable contraceptive combination of 90 mg dihydroxyprogesterone acetophenide with 6 mg estradiol enanthate, given once during each menstrual cycle between the 7th and 10th day, and preferably on the 8th day of the cycle, for a total of 17,576 cycles. Of these 1,904 women, 1,197 completed 12 cycles of use of the injectable combination. One subject became pregnant during the trial, resulting in a cumulative pregnancy rate of 0.07%. Principal reasons for discontinuation were personal, non-medical reasons, such as lost to follow-up, no longer wished to continue, protocol violation, desire to change to another contraceptive method, moved away, or other personal reasons. Mean weight of 1,901 subjects at admission to the trial was 53.5 ± 0.2 kg and this increased to 54.3 ± 0.3 kg after 12 cycles of use. Approximately 50% of subjects experienced menstrual bleeding similar to normal throughout the study period. The most frequent menstrual abnormality was irregular bleeding, experienced by approximately one-third of subjects.Submitted by Suelen Reis (suelen_suzane@hotmail.com) on 2013-01-16T11:28:26Z No. of bitstreams: 1 coutinho.pdf: 195605 bytes, checksum: 98465cdf654de2776a9b68a35d0bf153 (MD5)Made available in DSpace on 2013-01-16T11:28:26Z (GMT). No. of bitstreams: 1 coutinho.pdf: 195605 bytes, checksum: 98465cdf654de2776a9b68a35d0bf153 (MD5) Previous issue date: 2000http://dx.doi.org/10.1016/S0010-7824(00)00099-8reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinjectable contraceptivedihydroxyprogesterone acetophenideestradiol enanthateEfficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthateContraceptioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/7874/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINALcoutinho.pdfcoutinho.pdfapplication/pdf195605https://repositorio.ufba.br/bitstream/ri/7874/1/coutinho.pdf98465cdf654de2776a9b68a35d0bf153MD51TEXTcoutinho.pdf.txtcoutinho.pdf.txtExtracted texttext/plain17661https://repositorio.ufba.br/bitstream/ri/7874/3/coutinho.pdf.txt4969a55921060330323f5495c7edca83MD53ri/78742022-07-05 14:03:34.898oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:34Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate
dc.title.alternative.pt_BR.fl_str_mv Contraception
title Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate
spellingShingle Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate
Coutinho, Elsimar Metzker
injectable contraceptive
dihydroxyprogesterone acetophenide
estradiol enanthate
title_short Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate
title_full Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate
title_fullStr Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate
title_full_unstemmed Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate
title_sort Efficacy, acceptability, and clinical effects of a low-dose injectable contraceptive combination of dihydroxyprogesterone acetophenide and estradiol enanthate
author Coutinho, Elsimar Metzker
author_facet Coutinho, Elsimar Metzker
Spinola, Paulo
Tomaz, Geraldez
Morais, Kleber
Souza, Rosival Nassar de
Pinho Neto, João Sabino
Leal, Weydson de Barros
Hippolito, Silvia Bomfim
Abranches, Anthony D'Aurea
author_role author
author2 Spinola, Paulo
Tomaz, Geraldez
Morais, Kleber
Souza, Rosival Nassar de
Pinho Neto, João Sabino
Leal, Weydson de Barros
Hippolito, Silvia Bomfim
Abranches, Anthony D'Aurea
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Coutinho, Elsimar Metzker
Spinola, Paulo
Tomaz, Geraldez
Morais, Kleber
Souza, Rosival Nassar de
Pinho Neto, João Sabino
Leal, Weydson de Barros
Hippolito, Silvia Bomfim
Abranches, Anthony D'Aurea
Coutinho, Elsimar Metzker
Spinola, Paulo
Tomaz, Geraldez
Morais, Kleber
Souza, Rosival Nassar de
Pinho Neto, João Sabino
Leal, Weydson de Barros
Hippolito, Silvia Bomfim
Abranches, Anthony D'Aurea
dc.subject.por.fl_str_mv injectable contraceptive
dihydroxyprogesterone acetophenide
estradiol enanthate
topic injectable contraceptive
dihydroxyprogesterone acetophenide
estradiol enanthate
description Texto completo: acesso restrito. p. 277–280
publishDate 2000
dc.date.issued.fl_str_mv 2000
dc.date.accessioned.fl_str_mv 2013-01-16T11:28:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/7874
dc.identifier.issn.none.fl_str_mv 0010-7824
dc.identifier.number.pt_BR.fl_str_mv v. 61, n. 4
identifier_str_mv 0010-7824
v. 61, n. 4
url http://www.repositorio.ufba.br/ri/handle/ri/7874
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/S0010-7824(00)00099-8
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instname_str Universidade Federal da Bahia (UFBA)
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reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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