Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study

Detalhes bibliográficos
Autor(a) principal: Oliveira, Priscila Chagas
Data de Publicação: 2010
Outros Autores: Pinheiro, Antonio Luiz Barbosa, Reis Junior, João Alves, Castro, Isabelle C. V. de, Gurgel, Clarissa, Noia, Manuela Pimentel, Meireles, Gyselle Cynthia Silva, Cangussu, Maria Cristina Teixeira, Ramalho, Luciana Maria Pedreira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/12442
Resumo: Texto completo: acesso restrito. p.613-619
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spelling Oliveira, Priscila ChagasPinheiro, Antonio Luiz BarbosaReis Junior, João AlvesCastro, Isabelle C. V. deGurgel, ClarissaNoia, Manuela PimentelMeireles, Gyselle Cynthia SilvaCangussu, Maria Cristina TeixeiraRamalho, Luciana Maria PedreiraOliveira, Priscila ChagasPinheiro, Antonio Luiz BarbosaReis Junior, João AlvesCastro, Isabelle C. V. deGurgel, ClarissaNoia, Manuela PimentelMeireles, Gyselle Cynthia SilvaCangussu, Maria Cristina TeixeiraRamalho, Luciana Maria Pedreira2013-08-05T09:56:53Z20101549-5418http://www.repositorio.ufba.br/ri/handle/ri/12442v. 28, n. 5Texto completo: acesso restrito. p.613-619Aim: The aim of this study was to evaluate with light microscopy the healing process of third-degree burns on diabetic rats treated with polarized light (λ400–2000 nm, 20 or 40 J/cm2/session, 40 mW/cm2, 2.4 J/cm2/min, 5.5-cm beam diameter). Background: Uncontrolled diabetes mellitus causes severe disruption of the body's metabolism, including healing. Polarized light sources have been shown to be effective in improving healing in many situations. Animals and Methods: Diabetes mellitus was induced with streptozotocin (60 mg/kg) in 45 male Wistar albino rats, and a third-degree burn (1.5 by 1.5 cm) was created on the dorsum of each animal under general anesthesia. The animals were randomly distributed into three groups: control, 20 J/cm2, and 40 J/cm2. Each group was then divided into three subgroups based on time of death (7, 14, 21 d). Phototherapy (20 or 40 J/cm2 per session) was carried out immediately after the burning and repeated daily until the day before death. Following animal death, specimens were removed, embedded in paraffin, sectioned, and stained with hematoxylin and eosin (HE) or Sirius Red or immunomarked with CK AE1/AE3 antibody. Qualitative and semiquantitative analyses were performed under light microscopy. The results were statistically analyzed. Results: The animals treated with 20 J/cm2 showed significant differences with regard to revascularization and re-epithelialization. Although the 40 J/cm2 group showed stimulation of fibroblastic proliferation as an isolated feature, no other difference from the control was observed. Conclusion: Our results suggest that the use of polarized light at 20 J/cm2 effectively improves the healing of third-degree burns on diabetic animals at both early and late stages of repair.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-08-02T12:24:48Z No. of bitstreams: 1 pho%2E2009%2E2675.pdf: 751406 bytes, checksum: a2a021fee85e71c18feefdad7eef9415 (MD5)Approved for entry into archive by Rodrigo Meirelles(rodrigomei@ufba.br) on 2013-08-05T09:56:53Z (GMT) No. of bitstreams: 1 pho%2E2009%2E2675.pdf: 751406 bytes, checksum: a2a021fee85e71c18feefdad7eef9415 (MD5)Made available in DSpace on 2013-08-05T09:56:53Z (GMT). No. of bitstreams: 1 pho%2E2009%2E2675.pdf: 751406 bytes, checksum: a2a021fee85e71c18feefdad7eef9415 (MD5) Previous issue date: 2010http://dx.doi.org/10.1089/pho.2009.2675reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAPolarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical studyPhotomedicine and Laser Surgeryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINALpho%2E2009%2E2675.pdfpho%2E2009%2E2675.pdfapplication/pdf751406https://repositorio.ufba.br/bitstream/ri/12442/1/pho%252E2009%252E2675.pdfa2a021fee85e71c18feefdad7eef9415MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/12442/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTpho%2E2009%2E2675.pdf.txtpho%2E2009%2E2675.pdf.txtExtracted texttext/plain27368https://repositorio.ufba.br/bitstream/ri/12442/3/pho%252E2009%252E2675.pdf.txtf483885481c482a4ae4cf60485c04d1cMD53ri/124422022-07-05 14:03:44.46oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:44Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study
dc.title.alternative.pt_BR.fl_str_mv Photomedicine and Laser Surgery
title Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study
spellingShingle Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study
Oliveira, Priscila Chagas
title_short Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study
title_full Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study
title_fullStr Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study
title_full_unstemmed Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study
title_sort Polarized light (λ400-2000 nm) on third-degree burns in diabetic rats: Immunohistochemical study
author Oliveira, Priscila Chagas
author_facet Oliveira, Priscila Chagas
Pinheiro, Antonio Luiz Barbosa
Reis Junior, João Alves
Castro, Isabelle C. V. de
Gurgel, Clarissa
Noia, Manuela Pimentel
Meireles, Gyselle Cynthia Silva
Cangussu, Maria Cristina Teixeira
Ramalho, Luciana Maria Pedreira
author_role author
author2 Pinheiro, Antonio Luiz Barbosa
Reis Junior, João Alves
Castro, Isabelle C. V. de
Gurgel, Clarissa
Noia, Manuela Pimentel
Meireles, Gyselle Cynthia Silva
Cangussu, Maria Cristina Teixeira
Ramalho, Luciana Maria Pedreira
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Priscila Chagas
Pinheiro, Antonio Luiz Barbosa
Reis Junior, João Alves
Castro, Isabelle C. V. de
Gurgel, Clarissa
Noia, Manuela Pimentel
Meireles, Gyselle Cynthia Silva
Cangussu, Maria Cristina Teixeira
Ramalho, Luciana Maria Pedreira
Oliveira, Priscila Chagas
Pinheiro, Antonio Luiz Barbosa
Reis Junior, João Alves
Castro, Isabelle C. V. de
Gurgel, Clarissa
Noia, Manuela Pimentel
Meireles, Gyselle Cynthia Silva
Cangussu, Maria Cristina Teixeira
Ramalho, Luciana Maria Pedreira
description Texto completo: acesso restrito. p.613-619
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2013-08-05T09:56:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/12442
dc.identifier.issn.none.fl_str_mv 1549-5418
dc.identifier.number.pt_BR.fl_str_mv v. 28, n. 5
identifier_str_mv 1549-5418
v. 28, n. 5
url http://www.repositorio.ufba.br/ri/handle/ri/12442
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1089/pho.2009.2675
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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