High serum nitric oxide levels in patients with severe leptospirosis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2006 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/6307 |
Resumo: | RESTRITO |
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Maciel, Elves A. P.Athanazio, Daniel AbensurReis, Eliana A. G.Cunha, Fernando Q.Queiroz, AdrianoAlmeida, Deusdélia Teixeira deMcbride, Alan J. A.Ko, Albert I.Reis, Mitermayer Galvão dosMaciel, Elves A. P.Athanazio, Daniel AbensurReis, Eliana A. G.Cunha, Fernando Q.Queiroz, AdrianoAlmeida, Deusdélia Teixeira deMcbride, Alan J. A.Ko, Albert I.Reis, Mitermayer Galvão dos2012-07-04T14:04:32Z2012-07-04T14:04:32Z20060001-706Xhttp://www.repositorio.ufba.br/ri/handle/ri/6307v.100, n.3RESTRITOLeptospirosis is a globally distributed zoonosis of major public health importance and is associated with severe disease manifestations such as acute renal failure and pulmonary haemorrhage syndrome. However, the extent to which the pathogenesis of leptospirosis mimics sepsis caused by Gram-negative bacteria remains unknown. The aim of this study was to evaluate serum levels of nitric oxide (NO) in patients diagnosed with severe leptospirosis. Sera from 35 confirmed cases of severe leptospirosis and 13 healthy subjects were analysed. Patients with severe leptospirosis had significantly higher NO levels compared to healthy individuals (30.82 ± 10.90 μM versus 3.86 ± 1.34 μM, P < 0.001), indicating that this immune mediator plays a role in the underlying systemic inflammatory response.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2012-07-04T14:04:32Z No. of bitstreams: 1 789.pdf: 96249 bytes, checksum: ac92983daf6497c18de41cf11f60bf61 (MD5)Made available in DSpace on 2012-07-04T14:04:32Z (GMT). No. of bitstreams: 1 789.pdf: 96249 bytes, checksum: ac92983daf6497c18de41cf11f60bf61 (MD5) Previous issue date: 2006Acta Tropicahttp://dx.doi.org/10.1016/j.actatropica.2006.11.006reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALeptospirosisNitric oxideAcute renal failurePulmonary haemorrhageHigh serum nitric oxide levels in patients with severe leptospirosisActa Tropicainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL789.pdf789.pdfapplication/pdf96249https://repositorio.ufba.br/bitstream/ri/6307/1/789.pdfac92983daf6497c18de41cf11f60bf61MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6307/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT789.pdf.txt789.pdf.txtExtracted texttext/plain22416https://repositorio.ufba.br/bitstream/ri/6307/3/789.pdf.txt998bded73ac38bd0d279414ed9e57766MD53ri/63072022-07-05 14:03:52.051oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:52Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
High serum nitric oxide levels in patients with severe leptospirosis |
| dc.title.alternative.pt_BR.fl_str_mv |
Acta Tropica |
| title |
High serum nitric oxide levels in patients with severe leptospirosis |
| spellingShingle |
High serum nitric oxide levels in patients with severe leptospirosis Maciel, Elves A. P. Leptospirosis Nitric oxide Acute renal failure Pulmonary haemorrhage |
| title_short |
High serum nitric oxide levels in patients with severe leptospirosis |
| title_full |
High serum nitric oxide levels in patients with severe leptospirosis |
| title_fullStr |
High serum nitric oxide levels in patients with severe leptospirosis |
| title_full_unstemmed |
High serum nitric oxide levels in patients with severe leptospirosis |
| title_sort |
High serum nitric oxide levels in patients with severe leptospirosis |
| author |
Maciel, Elves A. P. |
| author_facet |
Maciel, Elves A. P. Athanazio, Daniel Abensur Reis, Eliana A. G. Cunha, Fernando Q. Queiroz, Adriano Almeida, Deusdélia Teixeira de Mcbride, Alan J. A. Ko, Albert I. Reis, Mitermayer Galvão dos |
| author_role |
author |
| author2 |
Athanazio, Daniel Abensur Reis, Eliana A. G. Cunha, Fernando Q. Queiroz, Adriano Almeida, Deusdélia Teixeira de Mcbride, Alan J. A. Ko, Albert I. Reis, Mitermayer Galvão dos |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Maciel, Elves A. P. Athanazio, Daniel Abensur Reis, Eliana A. G. Cunha, Fernando Q. Queiroz, Adriano Almeida, Deusdélia Teixeira de Mcbride, Alan J. A. Ko, Albert I. Reis, Mitermayer Galvão dos Maciel, Elves A. P. Athanazio, Daniel Abensur Reis, Eliana A. G. Cunha, Fernando Q. Queiroz, Adriano Almeida, Deusdélia Teixeira de Mcbride, Alan J. A. Ko, Albert I. Reis, Mitermayer Galvão dos |
| dc.subject.por.fl_str_mv |
Leptospirosis Nitric oxide Acute renal failure Pulmonary haemorrhage |
| topic |
Leptospirosis Nitric oxide Acute renal failure Pulmonary haemorrhage |
| description |
RESTRITO |
| publishDate |
2006 |
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2006 |
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2012-07-04T14:04:32Z |
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2012-07-04T14:04:32Z |
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info:eu-repo/semantics/article |
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http://www.repositorio.ufba.br/ri/handle/ri/6307 |
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0001-706X |
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v.100, n.3 |
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0001-706X v.100, n.3 |
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eng |
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openAccess |
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Acta Tropica |
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Acta Tropica |
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http://dx.doi.org/10.1016/j.actatropica.2006.11.006 |
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