Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair

Detalhes bibliográficos
Autor(a) principal: Marchionni, Antônio M. T.
Data de Publicação: 2010
Outros Autores: Medrado, Alena Ribeiro Alves Peixoto, Silva, Tânia Maria Correia, Fracassi, Larissa D., Pinheiro, Antonio Luiz Barbosa, Reis, Sílvia R. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/12389
Resumo: Texto completo: acesso restrito. p.639-646
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spelling Marchionni, Antônio M. T.Medrado, Alena Ribeiro Alves PeixotoSilva, Tânia Maria CorreiaFracassi, Larissa D.Pinheiro, Antonio Luiz BarbosaReis, Sílvia R. A.Marchionni, Antônio M. T.Medrado, Alena Ribeiro Alves PeixotoSilva, Tânia Maria CorreiaFracassi, Larissa D.Pinheiro, Antonio Luiz BarbosaReis, Sílvia R. A.2013-07-31T19:59:39Z20101549-5418http://www.repositorio.ufba.br/ri/handle/ri/12389v. 28, n. 5Texto completo: acesso restrito. p.639-646This study aimed to assess the effect of LLLT associated with and without dexamethasone on inflammation and wound healing in cutaneous surgical wounds. Background: Limited studies are directed at the possible interference of laser photobiomodulation on the formation of myofibroblasts, associated with an antiinflammatory drug. Methods and Materials: Standard skin wounds were performed on 80 Wistar rats, distributed into four groups: no treatment (sham group), laser only (λ670 nm, 9 mW, 0.031 W/cm2, 4 J/cm2, single dose after surgery), dexamethasone only (2 mg/kg 1 h before surgery), and laser with dexamethasone. Tissue was examined histologically to evaluate edema, presence of polymorphonuclear, mononuclear cells, and collagen. The analysis of myofibroblasts was assessed by immunohistochemistry and transmission electron microscopy. The intensity was rated semiquantitatively. Results: The results showed that laser and dexamethasone acted in a similar pattern to reduce acute inflammation. Collagen synthesis and myofibroblasts were more intense in the laser group (p = 0.048), whereas animals treated with dexamethasone showed lower results for these variables. In a combination of therapies, the synthesis of collagen and actin and desmin-positive cells was less than laser group. Conclusions: Laser was effective in reducing swelling and polymorphonuclear cells and accelerated tissue repair, even in the presence of dexamethasone.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-07-23T12:50:47Z No. of bitstreams: 1 pho%2E2009%2E2587.pdf: 495882 bytes, checksum: f9eb4a200f9c4baf0474c354bf8e627a (MD5)Approved for entry into archive by Flávia Ferreira(flaviaccf@yahoo.com.br) on 2013-07-31T19:59:39Z (GMT) No. of bitstreams: 1 pho%2E2009%2E2587.pdf: 495882 bytes, checksum: f9eb4a200f9c4baf0474c354bf8e627a (MD5)Made available in DSpace on 2013-07-31T19:59:39Z (GMT). No. of bitstreams: 1 pho%2E2009%2E2587.pdf: 495882 bytes, checksum: f9eb4a200f9c4baf0474c354bf8e627a (MD5) Previous issue date: 2010http://dx.doi.org/10.1089/pho.2009.2587reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALasersDexamethasoneCutaneous repairInfluence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repairPhotomedicine and Laser Surgeryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/12389/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINALpho%2E2009%2E2587.pdfpho%2E2009%2E2587.pdfapplication/pdf495882https://repositorio.ufba.br/bitstream/ri/12389/1/pho%252E2009%252E2587.pdff9eb4a200f9c4baf0474c354bf8e627aMD51TEXTpho%2E2009%2E2587.pdf.txtpho%2E2009%2E2587.pdf.txtExtracted texttext/plain30607https://repositorio.ufba.br/bitstream/ri/12389/3/pho%252E2009%252E2587.pdf.txt2aa27dc5ba8f8aa76d39fd87b5ca8722MD53ri/123892022-07-05 14:03:17.438oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:17Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair
dc.title.alternative.pt_BR.fl_str_mv Photomedicine and Laser Surgery
title Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair
spellingShingle Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair
Marchionni, Antônio M. T.
Lasers
Dexamethasone
Cutaneous repair
title_short Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair
title_full Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair
title_fullStr Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair
title_full_unstemmed Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair
title_sort Influence of laser (λ670 nm) and dexamethasone on the chronology of cutaneous repair
author Marchionni, Antônio M. T.
author_facet Marchionni, Antônio M. T.
Medrado, Alena Ribeiro Alves Peixoto
Silva, Tânia Maria Correia
Fracassi, Larissa D.
Pinheiro, Antonio Luiz Barbosa
Reis, Sílvia R. A.
author_role author
author2 Medrado, Alena Ribeiro Alves Peixoto
Silva, Tânia Maria Correia
Fracassi, Larissa D.
Pinheiro, Antonio Luiz Barbosa
Reis, Sílvia R. A.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Marchionni, Antônio M. T.
Medrado, Alena Ribeiro Alves Peixoto
Silva, Tânia Maria Correia
Fracassi, Larissa D.
Pinheiro, Antonio Luiz Barbosa
Reis, Sílvia R. A.
Marchionni, Antônio M. T.
Medrado, Alena Ribeiro Alves Peixoto
Silva, Tânia Maria Correia
Fracassi, Larissa D.
Pinheiro, Antonio Luiz Barbosa
Reis, Sílvia R. A.
dc.subject.por.fl_str_mv Lasers
Dexamethasone
Cutaneous repair
topic Lasers
Dexamethasone
Cutaneous repair
description Texto completo: acesso restrito. p.639-646
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2013-07-31T19:59:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/12389
dc.identifier.issn.none.fl_str_mv 1549-5418
dc.identifier.number.pt_BR.fl_str_mv v. 28, n. 5
identifier_str_mv 1549-5418
v. 28, n. 5
url http://www.repositorio.ufba.br/ri/handle/ri/12389
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1089/pho.2009.2587
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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